Intravenous chemotherapy with cisplatin for regional lymph node metastases of auricular VX2 carcinoma

Anticancer Research

Volumn 24, Issue 3 A, 2004, Pages 1785-1789

  Dunne A A ^a   Kuropkat, C ^a   Sapundzhiev, N ^a   Ramaswamy, A ^a   Sesterhenn, A ^a   Schulz, S ^a   Werner, Jochen A ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Animal model; Intravenous cisplatin therapy; Lymph node metastasis; VX2 carcinoma

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CISPLATIN; IODINATED POPPYSEED OIL; MITOXANTRONE; PACLITAXEL; SESAME SEED OIL; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CANCER MODEL; CANCER SURVIVAL; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG SCREENING; EAR CANCER; FEMALE; FOLLOW UP; HISTOPATHOLOGY; LUNG METASTASIS; LUNG PARENCHYMA; LYMPH NODE METASTASIS; METASTASIS POTENTIAL; NONHUMAN; OUTCOMES RESEARCH; PRIORITY JOURNAL; RABBIT; TOPOGRAPHY; TUMOR CELL; TUMOR NECROSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; EAR NEOPLASMS; EAR, EXTERNAL; FEMALE; INFUSIONS, INTRAVENOUS; LYMPHATIC METASTASIS; RABBITS;

EID: 3242701473     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Mandic R, Dünne AA, Ramaswamy A, Eikelkamp N, Plehn S, Schulz S, Moll R and Werner JA: Expression of MMP-2, MMP-3 and TIMP-3 in VX-2 carcinomas of New Zealand white rabbits. Anticancer Res 22: 3281-3284, 2002.
2. Van Es RJJ, Franssen O, Dullens HFJ, Bernsen MR, Bosman F, Hennik WE and Slootweg PJ: The VX carcinoma in the rabbit auricle as an experimental model for intra-arterial embolization of head and neck squamous cell carcinoma with dextran hydrogel microspheres. Lab Anim 33: 175-184, 1999.
3. van Es RJ, Nijsen JF, Dullens HF, Kicken M, van der Bilt A, Hennink W, Koole R and Slootweg PJ: Tumour embolization of the VX2 rabbit head and neck cancer model with Dextran hydrogel and Holmium-poly(L-lactic acid) microspheres: a radionuclide and histological pilot study. J Craniomaxillofac Surg 29: 289-297, 2001.
4. Harima Y, Harima K, Hasegawa T, Shikata N and Tanaka Y: Histopathological changes in rabbit uterus carcinoma after transcatheter arterial embolization using cisplatin. Cancer Chemother Pharmacol 38: 317-322, 1996.
5. Davidson T, Wallace J and Carnochan P: The rabbit as an experimental model for regional chemotherapy. 1. Intra-arterial hindlimb infusion. Lab Anim 20: 343-346, 1986.
6. Yoon CJ, Chung JW, Park JH, Yoon YH, Lee JW, Jeong SY and Chung H: Transcatheter arterial chemoembolization with paclitaxel-lipiodol solution in rabbit VX2 liver tumor. Radiology 229: 126-131, 2003.
7. Burgener FA and Barbaric ZL: Treatment of VX2 carcinomas in rabbits by percutaneous intratumoral injection of heated 0.9% NaCl solutions. Cancer Res 39: 3429-3434, 1979.
8. Tabaru K, Konno T, Oda T, Nagamitsu A, Ishimaru Y and Kitamura N: Treatment of VX2 carcinoma implanted in the liver with arterial and intraperitoneal administration of oily anticancer agents. Cancer Chemother Pharmacol 47: 149-154, 2001.
9. Kitamura M, Sugimachi K, Maekawa S, Kai H, Kuwano H and Matsuda H: Destruction of VX2 tumor in rabbits by hyperthermia plus bleomycin suspended in sesame oil. Cancer Treat Rep 70: 1263-1269, 1986.
10. Alexiou C, Jurgons R, Schmid RJ, Bergemann C, Henke J, Erhardt W, Huenges E and Parak F: Magnetic drug targeting - biodistribution of the magnetic carrier and the chemotherapeutic agent mitoxantrone after locoregional cancer treatment. J Drug Target 11: 139-149, 2003.
11. Natsuda Y, Sugimachi K, Ueo H, Matsuzaki K, Inokuchi K and Nakamura T: Experimental study on trans-nodal cancer chemotherapy for metastatic lymph nodes. Jpn J Surg 13: 368-372, 1983.
12. Werner JA, Dünne AA and Myers J: Functional anatomy of the lymphatic drainage system of the upper aerodigestive tract and its role in metastasis of squamous cell carcinoma. Head Neck 25: 322-332, 2003.
13. Dünne AA, Mandic R, Ramaswamy A, Plehn S, Schulz S, Lippert BM, Moll R and Werner JA: Lymphogenic metastatic spread of auricular VX2 carcinoma in New Zealand white rabbits. Anticancer Res 22: 3273-3279, 2002.
14. Dünne AA, Plehn S, Schulz S, Levermann A, Ramaswamy A, Lippert BM and Werner JA: Lymph node topography of the head and neck in New Zealand rabbits. Lab Anim UK 37: 37-43, 2003.
15. Denis F, Garaud P, Manceau A, Beutter P, Garand G, le Floch O and Calais G: Prognostic value of the number of involved nodes after neck dissection in oropharyngeal and oral cavity carcinoma. Cancer Radiother 5: 12-22, 2001.
16. Lefebvre JL, Buisset E, Van JT, Delobelle-Deroide A and Caty A: Lymph nodes as prognostic factors in pharyngolarynx SCC. In: Laryngeal Cancer (Smee R, Bridger GP, eds.). Amsterdam, Elsevier, 1994, pp. 589-592.
17. Ji W, Yu J and Guan C: Significance of pathological type in cervical lymph metastasis of laryngeal cancer. Lin Chuang Er Bi Yan Hou Ke Za Zhi 12: 291-292, 1998.
18. Shigetomi A, Kotoh T, Harada T, Morikawa S and Nakamura T: Development of an experimental model for spontaneous lymph node metastasis of human esophageal carcinoma in nude mice-histopathological analysis. Hum Cell 5: 273-281, 1992.
19. Mine H and Nakamura T: Mode of lymph node metastases in esophageal cancer induced in rabbits with VX2 carcinoma. Jpn J Surg 13: 236-245, 1983.
20. Steward HL, Snell KC, Dunham LJ and Schlyen SM: V2 carcinome, rabbit. In: Atlas of Tumor Pathology, Transplantable and Transmissible Tumors of Animals, section XII-fascicle 40. Washington, AFIP, 38-42, 1959.
21. Dünne AA, Schmidt A, Kuropkat C, Ramaswamy A, Schulz S and Werner JA: The auricular VX2 carcinoma - an animal model for sentinel node concept. In Vivo 17: 457-462, 2003.
22. Barry MA, Behnke CA and Eastman A: Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem Pharmacol 40: 2353-2362, 1990.
23. Kuo JH: Ultrastructural study on effects of cisplatin on VX2 carcinoma cells. Bull Tokyo Med Dent Univ 37: 35-50, 1990.
24. Harima Y, Harima K, Hasegawa T, Shikata N and Tanaka Y: Transcatheter arterial embolization with cisplatin: apoptosis in VX2 tumour uterus transplants. Anticancer Res 16: 193-199, 1996.