In vivo and in vitro effect of latex of Calotropis procera on gastrointestinal smooth muscles

Journal of Ethnopharmacology

Volumn 93, Issue 2-3, 2004, Pages 377-379

  Kumar, V L ^a   Shivkar, Y M ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Calotropis procera; Desensitization; Latex; Smooth muscles

Indexed keywords

CALOTROPIS PROCERA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALOTROPIS; CONTROLLED STUDY; DESENSITIZATION; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; GASTROINTESTINAL TRACT; ILEUM; LOW DRUG DOSE; MALE; NONHUMAN; RABBIT; RAT; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTION; STOMACH FUNDUS;

ADMINISTRATION, ORAL; ANIMALS; CALOTROPIS; DIGESTIVE SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL MOTILITY; LATEX; MALE; MUSCLE, SMOOTH; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; RATS; RATS, WISTAR;

EID: 3242692566     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2004.04.013     Document Type: Article

References (11)

1. Huidobro-Toro J.P., Foree B. Dual agonist-antagonist effects of 5-hydroxytryptamine (5-HT) in the guinea pig ileum: evidence for a selective receptor desensitization effect. European Journal of Pharmacology. 6:1980;335-345
2. Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants. Lolit Mohan Basu, Allahabad, p. 1606.
3. Kumar S., Dewan S., Sangraula H., Kumar V.L. Antidiarrhoeal activity of latex of Calotropis procera. Journal of Ethnopharmacology. 76:2001;115-118
4. Mascolo N., Izzo A.A., Autore G., Barbato F., Capasso F. Nitric oxide and castor-oil induced diarrhoea. Journal of Pharmacology and Experimental Therapeutics. 268:1994;291-295
5. Perry, W.L.M., 1968. Pharmacological Experiments on Isolated Preparations. E & S Livingstone Ltd., Edinburgh.
6. 3 receptors in control of mouse intestinal motility in vivo and in vitro: comparison with alpha2-adrenoceptors. Digestive Diseases and Sciences. 47:2002;1065-1072
7. Robert A., Nezamis J.E., Lancaster C., Hanchar A.J., Klepper M.S. Enteropooling assay: a test for diarrhoea produced by prostaglandins. Prostaglandins. 11:1976;809-828
8. Satyavati, G.V., Raina, M.K., Sharma, M., 1976. Medicinal plants of India. Indian Council of Medical Research, New Delhi Vol. 1, pp. 167-170.
9. Sharma G.K. Calotropis procera and Calotropis gigantea. Indian Journal of Veterinary Sciences. 4:1934;63-74
10. Shivkar Y.M., Kumar V.L. Histamine mediates the pro-inflammatory effect of latex of Calotropis procera in rats. Mediators of Inflammation. 12:2003;299-302
11. The Wealth of India, 1992. Raw Materials. Publication and Information Directorate, vol. 3, CSIR, New Delhi, pp. 78-84.