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Volumn 28, Issue 5, 2004, Pages 372-378

Quantitation of metabolites of the nerve agents sarin, soman, cyclohexylsarin, VX, and Russian VX in human urine using isotope-dilution gas chromatography-tandem mass spectrometry

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; CYCLOSARIN; ISOBUTYL METHYLPHOSPHONIC ACID; O (2 METHYLPROPYL) 2 (DIETHYLAMINO)ETHYLMETHYLPHOSPHONOTHIOLATE; ORGANOPHOSPHORUS COMPOUND; SARIN; SOMAN; UNCLASSIFIED DRUG;

EID: 3242677043     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/28.5.372     Document Type: Article
Times cited : (61)

References (20)
  • 1
    • 0028294045 scopus 로고
    • Application of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry, and tandem mass spectrometry, to the analysis and identification of degradation products of chemical warfare agents
    • R.M. Black, R.J. Clarke, R.J. Read, and M.T.J. Reid. Application of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry, and tandem mass spectrometry, to the analysis and identification of degradation products of chemical warfare agents. J. Chromatogr. A 662: 301-321 (1994).
    • (1994) J. Chromatogr. A , vol.662 , pp. 301-321
    • Black, R.M.1    Clarke, R.J.2    Read, R.J.3    Reid, M.T.J.4
  • 2
    • 0031658508 scopus 로고    scopus 로고
    • Identification of metabolites of nerve agent VX in serum collected from a victim
    • H. Tsuchihashi, M. Katagi, M. Nishikawa, and M. Tatsuno. Identification of metabolites of nerve agent VX in serum collected from a victim. J. Anal. Toxicol. 22: 383-388 (1998).
    • (1998) J. Anal. Toxicol. , vol.22 , pp. 383-388
    • Tsuchihashi, H.1    Katagi, M.2    Nishikawa, M.3    Tatsuno, M.4
  • 3
    • 0030808137 scopus 로고    scopus 로고
    • Method for the analysis of the methylphosphonic acid metabolites of sarin and its ethanol-substituted analogue in urine as applied to the victims of the Tokyo sarin disaster
    • M. Minami, D.-M. Hui, M. Katsumata, H. Inagaki, and C.A. Boulet. Method for the analysis of the methylphosphonic acid metabolites of sarin and its ethanol-substituted analogue in urine as applied to the victims of the Tokyo sarin disaster. J. Chromatogr. B 695: 237-244 (1997).
    • (1997) J. Chromatogr. B , vol.695 , pp. 237-244
    • Minami, M.1    Hui, D.-M.2    Katsumata, M.3    Inagaki, H.4    Boulet, C.A.5
  • 5
    • 0031724974 scopus 로고    scopus 로고
    • Quantitative analysis of O-isopropyl methylphosphonic acid in serum samples of Japanese citizens allegedly exposed to sarin: Estimation of internal dosage
    • D. Noort, A.G. Hulst, D.H.J.M. Platenburg, M. Polhuijs, and H.P. Benschop. Quantitative analysis of O-isopropyl methylphosphonic acid in serum samples of Japanese citizens allegedly exposed to sarin: estimation of internal dosage. Arch. Toxicol. 72: 671-675 (1998).
    • (1998) Arch. Toxicol. , vol.72 , pp. 671-675
    • Noort, D.1    Hulst, A.G.2    Platenburg, D.H.J.M.3    Polhuijs, M.4    Benschop, H.P.5
  • 6
    • 0031474414 scopus 로고    scopus 로고
    • Analysis of methylphosphonic acid, ethyl methylphosphonic acid and isopropyl methylphosphonic acid at low microgram per liter levels in groundwater
    • G.A. Sega, B.A. Tomkins, and W.H. Greist. Analysis of methylphosphonic acid, ethyl methylphosphonic acid and isopropyl methylphosphonic acid at low microgram per liter levels in groundwater. J. Chromatogr. A 790: 143-152 (1997).
    • (1997) J. Chromatogr. A , vol.790 , pp. 143-152
    • Sega, G.A.1    Tomkins, B.A.2    Greist, W.H.3
  • 8
    • 0001353983 scopus 로고
    • Ion chromatographic separation of closely related nerve agent degradation products using an organic modifier to provide selectivity
    • A.F. Kingery and H.E. Allen. Ion chromatographic separation of closely related nerve agent degradation products using an organic modifier to provide selectivity. Anal. Chem. 66: 155-159 (1994).
    • (1994) Anal. Chem. , vol.66 , pp. 155-159
    • Kingery, A.F.1    Allen, H.E.2
  • 9
    • 0030753532 scopus 로고    scopus 로고
    • Determination of the main hydrolysis products of organophosphorus nerve agents, methylphosphonic acids, in human serum by indirect photometric detection ion chromatography
    • M. Katagi, M. Nishikawa, M. Tatsuno, and H. Tsuchihashi. Determination of the main hydrolysis products of organophosphorus nerve agents, methylphosphonic acids, in human serum by indirect photometric detection ion chromatography. J. Chromatogr. B 698: 81-88 (1997).
    • (1997) J. Chromatogr. B , vol.698 , pp. 81-88
    • Katagi, M.1    Nishikawa, M.2    Tatsuno, M.3    Tsuchihashi, H.4
  • 10
    • 0032167672 scopus 로고    scopus 로고
    • Quantitative analysis of chemical warfare agent degradation products in reaction masses using capillary electrophoresis
    • A.E. Nassar, S.V. Lucas, C.A. Myler, W.R. Jones, M. Campisano, and L.D. Hoffland. Quantitative analysis of chemical warfare agent degradation products in reaction masses using capillary electrophoresis. Anal. Chem. 70: 3598-3604 (1998).
    • (1998) Anal. Chem. , vol.70 , pp. 3598-3604
    • Nassar, A.E.1    Lucas, S.V.2    Myler, C.A.3    Jones, W.R.4    Campisano, M.5    Hoffland, L.D.6
  • 11
    • 0028814772 scopus 로고
    • Analysis of nerve agent degradation products using capillary ion electrophoresis
    • S.A. Oehrle and P.C. Bossle. Analysis of nerve agent degradation products using capillary ion electrophoresis. J. Chromatogr. B 692: 247-252 (1995).
    • (1995) J. Chromatogr. B , vol.692 , pp. 247-252
    • Oehrle, S.A.1    Bossle, P.C.2
  • 12
    • 0032983143 scopus 로고    scopus 로고
    • On-line solid-phase extraction liquid chromatography-continuous flow fast atom bombardment mass spectrometric and tandem mass spectrometric determination of hydrolysis products of nerve agents alkyl methylphosphonic acids by p-bromophenacyl derivatization
    • M. Katagi, M. Tatsuno, M. Nishikawa, and H. Tsuchihashi. On-line solid-phase extraction liquid chromatography-continuous flow fast atom bombardment mass spectrometric and tandem mass spectrometric determination of hydrolysis products of nerve agents alkyl methylphosphonic acids by p-bromophenacyl derivatization. J. Chromatogr. 833: 169-179 (1999).
    • (1999) J. Chromatogr. , vol.833 , pp. 169-179
    • Katagi, M.1    Tatsuno, M.2    Nishikawa, M.3    Tsuchihashi, H.4
  • 13
    • 0029120955 scopus 로고
    • Trace determination of alkylmethylphosphonic acids in environmental and biological samples using gas chromatography/negative-ion chemical ionization mass spectrometry and tandem mass spectrometry
    • S.-A. Fredriksson, L.-G. Hammarstrom, L. Henriksson, and H.-A. Lakso. Trace determination of alkylmethylphosphonic acids in environmental and biological samples using gas chromatography/negative-ion chemical ionization mass spectrometry and tandem mass spectrometry. J. Mass Spectrom. 30: 1133-1143 (1995).
    • (1995) J. Mass Spectrom. , vol.30 , pp. 1133-1143
    • Fredriksson, S.-A.1    Hammarstrom, L.-G.2    Henriksson, L.3    Lakso, H.-A.4
  • 14
    • 0029617648 scopus 로고
    • Gas chromatographic determination and gas chromtographic-mass spectrometric determination of dialkyl phosphates via extractive pentafluorobenzylation using a polymeric phase transfer catalyst
    • A. Miki, H. Tsuchihashi, K. Ueda, and M. Yamashita. Gas chromatographic determination and gas chromtographic-mass spectrometric determination of dialkyl phosphates via extractive pentafluorobenzylation using a polymeric phase transfer catalyst. J. Chromatogr. A 718: 383-389 (1995).
    • (1995) J. Chromatogr. A , vol.718 , pp. 383-389
    • Miki, A.1    Tsuchihashi, H.2    Ueda, K.3    Yamashita, M.4
  • 15
    • 0033001849 scopus 로고    scopus 로고
    • Determination of alkylmethylphosphonic acids, the main metabolites of organophosphorus nerve agents, in biofluids by gas chromatography-mass spectrometry and liquid-liquid solid-phase transfer-catalyzed pentafluorobenzylation
    • A. Miki, M. Katagi, H. Tsuchihashi, and M. Yamashita. Determination of alkylmethylphosphonic acids, the main metabolites of organophosphorus nerve agents, in biofluids by gas chromatography-mass spectrometry and liquid-liquid solid-phase transfer-catalyzed pentafluorobenzylation. J. Anal. Toxicol. 23: 86-93 (1999).
    • (1999) J. Anal. Toxicol. , vol.23 , pp. 86-93
    • Miki, A.1    Katagi, M.2    Tsuchihashi, H.3    Yamashita, M.4
  • 16
    • 0036141567 scopus 로고    scopus 로고
    • Quantitation of organophosphorus nerve agent metabolites in human urine using isotope dilution gas chromatography-tandem mass spectrometry
    • W.J. Driskell, M. Shih, L.L. Needham, and D.B. Barr. Quantitation of organophosphorus nerve agent metabolites in human urine using isotope dilution gas chromatography-tandem mass spectrometry. J. Anal. Toxicol. 26: 6-10 (2002).
    • (2002) J. Anal. Toxicol. , vol.26 , pp. 6-10
    • Driskell, W.J.1    Shih, M.2    Needham, L.L.3    Barr, D.B.4
  • 17
    • 0030884927 scopus 로고    scopus 로고
    • New method for retrospective detection of exposure to organophosphorus anticholinesterases: Application to alleged sarin victims of Japanese terrorists
    • M. Polhuijs, J.P. Langenberg, and H.P. Benschop. New method for retrospective detection of exposure to organophosphorus anticholinesterases: application to alleged sarin victims of Japanese terrorists. Toxicol. Appl. Pharmacol. 146: 156-161 (1997).
    • (1997) Toxicol. Appl. Pharmacol. , vol.146 , pp. 156-161
    • Polhuijs, M.1    Langenberg, J.P.2    Benschop, H.P.3
  • 18
    • 0022384657 scopus 로고
    • Synthesis of [14C]methylphosphonic difluoride
    • W.E. Bechtold and A.R. Dahl. Synthesis of [14C]methylphosphonic difluoride. J. Labeled Compd. Radiopharm. 22(11): 1181-1186 (1985).
    • (1985) J. Labeled Compd. Radiopharm. , vol.22 , Issue.11 , pp. 1181-1186
    • Bechtold, W.E.1    Dahl, A.R.2
  • 19
    • 0030055359 scopus 로고    scopus 로고
    • Laboratory precision performance: State of the art versus operating specifications that assure analytical quality
    • J.O. Westgard, N. Bawa, J.W. Ross, and N.S. Lawson. Laboratory precision performance: state of the art versus operating specifications that assure analytical quality. Arch. Pathol. Lab. Med. 120: 621-625 (1996).
    • (1996) Arch. Pathol. Lab. Med. , vol.120 , pp. 621-625
    • Westgard, J.O.1    Bawa, N.2    Ross, J.W.3    Lawson, N.S.4
  • 20
    • 0021021760 scopus 로고
    • American Chemical Society Committee Report. Principles of environmental measurement
    • American Chemical Society Committee Report. Principles of environmental measurement. Anal. Chem. 55: 2210-2218 (1983).
    • (1983) Anal. Chem. , vol.55 , pp. 2210-2218


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.