Pharmacokinetic properties and tolerability of single-dose terbutaline in patients with severe asthma treated in the pediatric intensive care unit

Current Therapeutic Research - Clinical and Experimental

Volumn 65, Issue 1, 2004, Pages 98-109

  Lebovitz, Daniel J ^a,b   Smith, Paul G ^a,b   O'Riordan, Maryann ^a,b   Reed, Michael D ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

asthma; children; intensive care; pharmacokinetics; terbutaline

Indexed keywords

TERBUTALINE;

ADOLESCENT; ARTERY CATHETER; ARTICLE; ASTHMA; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE EXACERBATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HUMAN; HYPOTENSION; INFANT; INTENSIVE CARE; MAJOR CLINICAL STUDY; MALE; PEDIATRICS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STEADY STATE; TACHYCARDIA;

EID: 3242674235     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(04)90009-4     Document Type: Article

References (17)

1. Akinbami L.J., Schoendorf K.C. Trends in childhood asthma: Prevalence, health care utilization, and mortality. Pediatrics. 110:2002;315-322
2. Mannino D.M., Homa D.M., Akinbami L.J., et al. Surveillance for asthma - United States, 1980-1999. MMWR Surveill Summ. 51:2002;1-13
3. Stempel D.A. The pharmacologic management of childhood asthma. Pediatr Clin North Am. 50:2003;609-629
4. Roberts J.S., Bratton S.L., Brogan T.V. Acute severe asthma: Differences in therapies and outcomes among pediatric intensive care units. Crit Care Med. 30:2002;581-585
5. Biarent D. Therapeutic strategies in near fatal asthma in children. Pediatr Pulmonol. 23:2001;90-93. (Suppl)
6. Hultquist C., Lindberg C., Nyberg L., et al. Pharmacokinetics of intravenous terbutaline in asthmatic children. Dev Pharmacol Ther. 13:1989;11-20
7. Fuglsang G., Pedersen S., Borgström L. Dose-response relationships of intravenously administered terbutaline in children with asthma. J Pediatr. 114:1989;315-320
8. US Dept of Health and Human Services, National Institutes of Health, National Asthma Education Program Expert Panel. Guidelines for the Diagnosis and Management of Asthma. 2nd ed Publication no. 91-3042. August 1991;US Dept of Health and Human Services, National Institutes of Health, Bethesda, Md
9. Bohn D., Kalloghlian A., Jenkins J., et al. Intravenous salbutamol in the treatment of status asthmaticus in children. Crit Care Med. 12:1984;892-896
10. Edholm L.E., Kennedy B.M., Bergquist S. Multidimensional column liquid chromatography with electrochemical detection for the analysis of terbutaline in human plasma. Eur J Respir Dis Suppl. 134:1984;33-40
11. Gibaldi M. Pharmacokinetics. 2nd ed:1982;Marcel Dekker, New York
12. Spahn J.D., Szefler S.J. Childhood asthma: New insights into management. J Allergy Clin Immunol. 109:2002;3-13
13. Suissa S., Ernst P., Kezouh A. Regular use of inhaled corticosteroids and the long term prevention of hospitalisation for asthma. Thorax. 57:2002;880-884
14. Hochhaus G., Mollmann H. Pharmacokinetic/pharmacodynamic characteristics of the beta-2-agonists terbutaline, salbutamol and fenoterol. Int J Clin Pharmacol Ther Toxicol. 30:1992;342-362
15. Borgstrom L., Nyberg L., Jonsson S., et al. Pharmacokinetic evaluation in man of terbutaline given as separate enantiomers and as the racemate. Br J Clin Pharmacol. 27:1989;49-56
16. Hemstreet M.P., Miles M.V., Rutland R.O. Effect of intravenous isoproterenol on theophylline kinetics. J Allergy Clin Immunol. 69:1982;360-364
17. O'Rourke P.P., Crone R.K. Effect of isoproterenol on measured theophylline levels. Crit Care Med. 12:1984;373-375