-
1
-
-
0037432067
-
Slowing Parkinson's disease progression: Recent dopamine agonist trials
-
Ahlskog, J.E. (2003) Slowing Parkinson's disease progression: recent dopamine agonist trials. Neurology, 60, 381-9.
-
(2003)
Neurology
, vol.60
, pp. 381-389
-
-
Ahlskog, J.E.1
-
2
-
-
0035353725
-
Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature
-
Ahlskog, J.E. and Muenter, M.D. (2001) Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov. Disord, 16, 448-58.
-
(2001)
Mov. Disord.
, vol.16
, pp. 448-458
-
-
Ahlskog, J.E.1
Muenter, M.D.2
-
3
-
-
0037638809
-
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial
-
Aisen, P.S., Schafer, K.A., Grundman, M., Pfeiffer, E., Sano, M., Davis, K.L., Farlow, M.R., Jin, S., Thomas, R.G., and Thal, L.J. (2003) Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial. JAMA, 289, 2819-26.
-
(2003)
JAMA
, vol.289
, pp. 2819-2826
-
-
Aisen, P.S.1
Schafer, K.A.2
Grundman, M.3
Pfeiffer, E.4
Sano, M.5
Davis, K.L.6
Farlow, M.R.7
Jin, S.8
Thomas, R.G.9
Thal, L.J.10
-
4
-
-
0030878073
-
Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
-
Alam, Z.I., Jenner, A., Daniel, S.E., Lees, A.J., Cairns, N., Marsden, C.D., Jenner, P., and Halliwell, B. (1997) Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J. Neurochem., 69, 1196-203.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
Jenner, P.7
Halliwell, B.8
-
5
-
-
0037432040
-
Initial agonist treatment of Parkinson disease: A critique
-
Albin, R.L. and Frey, K.A. (2003) Initial agonist treatment of Parkinson disease: a critique. Neurology, 60, 390-4.
-
(2003)
Neurology
, vol.60
, pp. 390-394
-
-
Albin, R.L.1
Frey, K.A.2
-
6
-
-
0026609559
-
Alternative excitotoxic hypothesis
-
Albin, R.L. and Greenamyre, J.T. (1992) Alternative excitotoxic hypothesis. Neurology, 42, 733-738.
-
(1992)
Neurology
, vol.42
, pp. 733-738
-
-
Albin, R.L.1
Greenamyre, J.T.2
-
7
-
-
0037238085
-
Parkinson's disease, smoking and family history: Meta-analysis
-
Allam, M.F., Del Castillo, A.S., and Navajas, R.F. (2003) Parkinson's disease, smoking and family history: meta-analysis. Eur. J. Neurol., 10, 59-62.
-
(2003)
Eur. J. Neurol.
, vol.10
, pp. 59-62
-
-
Allam, M.F.1
Del Castillo, A.S.2
Navajas, R.F.3
-
8
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames, B.N., Shigenaga, M.K., and Hagen, T.M. (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA, 90, 7915-22.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
9
-
-
0034743672
-
Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease
-
Andreassen, O.A., Dedeoglu, A., Ferrante, R.J., Jenkins, B.G., Ferrante, K.L., Thomas, M., Friedlich, A., Browne, S.E., Schilling, G., Borchelt, D.R., Hersch, S.M., Ross, C.A., and Beal, M.F. (2001) Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease. Neurobiol. Dis., 8, 479-91.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 479-491
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Ferrante, R.J.3
Jenkins, B.G.4
Ferrante, K.L.5
Thomas, M.6
Friedlich, A.7
Browne, S.E.8
Schilling, G.9
Borchelt, D.R.10
Hersch, S.M.11
Ross, C.A.12
Beal, M.F.13
-
10
-
-
0030738721
-
Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging
-
Anglade, P., Vyas, S., Hirsch, E.C., and Agid, Y. (1997) Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging. Histol. Histopathol., 12, 603-10.
-
(1997)
Histol. Histopathol.
, vol.12
, pp. 603-610
-
-
Anglade, P.1
Vyas, S.2
Hirsch, E.C.3
Agid, Y.4
-
11
-
-
0031715398
-
NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy
-
Arima, K., Ueda, K., Sunohara, N., Arakawa, K., Hirai, S., Nakamura, M., Tonozuka-Uehara, H., and Kawai, M. (1998) NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy. Acta Neuropathol. (Berl.), 96, 439-44.
-
(1998)
Acta Neuropathol. (Berl.)
, vol.96
, pp. 439-444
-
-
Arima, K.1
Ueda, K.2
Sunohara, N.3
Arakawa, K.4
Hirai, S.5
Nakamura, M.6
Tonozuka-Uehara, H.7
Kawai, M.8
-
12
-
-
0037432281
-
Caffeine, postmenopausal estrogen, and risk of Parkinson's disease
-
Ascherio, A., Chen, H., Schwarzschild, M.A., Zhang, S.M., Colditz, G.A., and Speizer, F.E. (2003) Caffeine, postmenopausal estrogen, and risk of Parkinson's disease. Neurology, 60, 790-5.
-
(2003)
Neurology
, vol.60
, pp. 790-795
-
-
Ascherio, A.1
Chen, H.2
Schwarzschild, M.A.3
Zhang, S.M.4
Colditz, G.A.5
Speizer, F.E.6
-
13
-
-
0034950069
-
Prospective study of caffeine consumption and risk of Parkinson's disease in men and women
-
Ascherio, A., Zhang, S.M., Hernan, M.A., Kawachi, I., Colditz, G.A., Speizer, F.E., and Willett, W.C. (2001) Prospective study of caffeine consumption and risk of Parkinson's disease in men and women. Ann. Neurol., 50, 56-63.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 56-63
-
-
Ascherio, A.1
Zhang, S.M.2
Hernan, M.A.3
Kawachi, I.4
Colditz, G.A.5
Speizer, F.E.6
Willett, W.C.7
-
14
-
-
0032603684
-
Localization of adenosine A2A receptors in brain: Therapeutic implications
-
Augood, S.J. (1999) Localization of adenosine A2A receptors in brain: therapeutic implications. Adv. Neurol, 80, 105-9.
-
(1999)
Adv. Neurol.
, vol.80
, pp. 105-109
-
-
Augood, S.J.1
-
15
-
-
0031930771
-
Glial pathology but absence of apoptotic nigral neurons in long- standing Parkinson's disease
-
Banati, R.B., Daniel, S.E., and Blunt, S.B. (1998) Glial pathology but absence of apoptotic nigral neurons in long- standing Parkinson's disease. Mov. Disord., 13, 221-7.
-
(1998)
Mov. Disord.
, vol.13
, pp. 221-227
-
-
Banati, R.B.1
Daniel, S.E.2
Blunt, S.B.3
-
16
-
-
0034237719
-
Energetics in the pathogenesis of neurodegenerative diseases
-
Beal, M.F. (2000) Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci., 23, 298-304.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 298-304
-
-
Beal, M.F.1
-
17
-
-
0036570159
-
Oxidatively modified proteins in aging and disease
-
Beal, M.F. (2002) Oxidatively modified proteins in aging and disease. Free Radic. Biol. Med., 32, 797-803.
-
(2002)
Free Radic. Biol. Med.
, vol.32
, pp. 797-803
-
-
Beal, M.F.1
-
18
-
-
0037379314
-
Bioenergetic approaches for neuroprotection in Parkinson's disease
-
discussion S47-8
-
Beal, M.F. (2003) Bioenergetic approaches for neuroprotection in Parkinson's disease. Ann. Neurol., 53 Suppl. 3, S39-47; discussion S47-8.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Beal, M.F.1
-
19
-
-
0031594295
-
Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice
-
Beal, M.F., Matthews, R.T., Tieleman, A., and Shults, C.W. (1998) Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice. Brain Res., 783, 109-14.
-
(1998)
Brain Res.
, vol.783
, pp. 109-114
-
-
Beal, M.F.1
Matthews, R.T.2
Tieleman, A.3
Shults, C.W.4
-
20
-
-
0026638409
-
Inflammatory cytokines within the central nervous system: Sources, function, and mechanism of action
-
Benveniste, E.N. (1992) Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action. Am. J. Physiol., 263, C1-16.
-
(1992)
Am. J. Physiol.
, vol.263
-
-
Benveniste, E.N.1
-
21
-
-
0036793929
-
Mechanistic approaches to Parkinson's disease
-
Betarbet, R., Sherer, T.B., Di Monte, D.A., and Greenamyre, J.T. (2002) Mechanistic approaches to Parkinson's disease. Brain Pathology, 12, 499-510.
-
(2002)
Brain Pathology
, vol.12
, pp. 499-510
-
-
Betarbet, R.1
Sherer, T.B.2
Di Monte, D.A.3
Greenamyre, J.T.4
-
22
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet, R., Sherer, T.B., MacKenzie, G., Garcia-Osuna, M., Panov, A.V., and Greenamyre, J.T. (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci., 3, 1301-6.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
23
-
-
0034672304
-
Towards a neuroprotective gene therapy for Parkinson's disease: Use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
-
Bjorklund, A., Kirik, D., Rosenblad, C., Georgievska, B., Lundberg, C., and Mandel, R.J. (2000) Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model. Brain Res., 886, 82-98.
-
(2000)
Brain Res.
, vol.886
, pp. 82-98
-
-
Bjorklund, A.1
Kirik, D.2
Rosenblad, C.3
Georgievska, B.4
Lundberg, C.5
Mandel, R.J.6
-
24
-
-
0034993599
-
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
-
Blum, D., Torch, S., Lambeng, N., Nissou, M., Benabid, A.L., Sadoul, R., and Verna, J.M. (2001) Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog. Neurobiol., 65, 135-72.
-
(2001)
Prog. Neurobiol.
, vol.65
, pp. 135-172
-
-
Blum, D.1
Torch, S.2
Lambeng, N.3
Nissou, M.4
Benabid, A.L.5
Sadoul, R.6
Verna, J.M.7
-
25
-
-
0029417080
-
Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients
-
Blum-Degen, D., Muller, T., Kuhn, W., Gerlach, M., Przuntek, H., and Riederer, P. (1995) Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. Neurosci. Lett., 202, 17-20.
-
(1995)
Neurosci. Lett.
, vol.202
, pp. 17-20
-
-
Blum-Degen, D.1
Muller, T.2
Kuhn, W.3
Gerlach, M.4
Przuntek, H.5
Riederer, P.6
-
26
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak, H., Del Tredici, K., Rub, U., de Vos, R.A., Jansen Steur, E.N., and Braak, E. (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging, 24, 197-211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
27
-
-
0031668924
-
The early diagnosis of Parkinson's disease
-
Brooks, D.J. (1998) The early diagnosis of Parkinson's disease. Ann. Neurol., 44, S10-8.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Brooks, D.J.1
-
28
-
-
0037378772
-
Imaging end points for monitoring neuroprotection in Parkinson's disease
-
discussion S118-9
-
Brooks, D.J. (2003) Imaging end points for monitoring neuroprotection in Parkinson's disease. Ann. Neurol., 53 Suppl. 3, S110-8; discussion S118-9.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Brooks, D.J.1
-
29
-
-
0027515957
-
NMDA antagonists partially protect against MPTP induced neurotoxicity in mice
-
Brouillet, E. and Beal, M.F. (1993) NMDA antagonists partially protect against MPTP induced neurotoxicity in mice. NeuroRep., 4, 387-90.
-
(1993)
NeuroRep.
, vol.4
, pp. 387-390
-
-
Brouillet, E.1
Beal, M.F.2
-
30
-
-
0028033379
-
Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10
-
Brouillet, E., Henshaw, D.R., Schulz, J.B., and Beal, M.F. (1994) Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10. Neurosci. Lett., 177, 58-62.
-
(1994)
Neurosci. Lett.
, vol.177
, pp. 58-62
-
-
Brouillet, E.1
Henshaw, D.R.2
Schulz, J.B.3
Beal, M.F.4
-
31
-
-
0034237402
-
Neurobehavioral aspects of antioxidants in aging
-
Cantuti-Castelvetri, I., Shukitt-Hale, B., and Joseph, J.A. (2000) Neurobehavioral aspects of antioxidants in aging. Int. J. Dev. Neurosci., 18, 367-81.
-
(2000)
Int. J. Dev. Neurosci.
, vol.18
, pp. 367-381
-
-
Cantuti-Castelvetri, I.1
Shukitt-Hale, B.2
Joseph, J.A.3
-
32
-
-
0034959811
-
Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain
-
Chauhan, N.B., Siegel, G.J., and Lee, J.M. (2001) Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain. J. Chem. Neuroanat., 21, 277-88.
-
(2001)
J. Chem. Neuroanat.
, vol.21
, pp. 277-288
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lee, J.M.3
-
33
-
-
0041653249
-
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
-
Chen, H., Zhang, S.M., Hernan, M.A., Schwarzschild, M.A., Willett, W.C., Colditz, G.A., Speizer, F.E., and Ascherio, A. (2003) Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease. Arch. Neurol., 60, 1059-64.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 1059-1064
-
-
Chen, H.1
Zhang, S.M.2
Hernan, M.A.3
Schwarzschild, M.A.4
Willett, W.C.5
Colditz, G.A.6
Speizer, F.E.7
Ascherio, A.8
-
34
-
-
0035874345
-
Neuroprotection by caffiene and A2a adenosine receptor inactivation in a model of Parkinson's disease
-
RC143
-
Chen, J.-F., Xu, K., Petzer, J.P., Staal, R., Xu, Y.-H., Beilstein, M., Sonsalla, P.K., Castagnoli, K., Castagnoli, N., and Schwarzschild, M.A. (2001) Neuroprotection by caffiene and A2a adenosine receptor inactivation in a model of Parkinson's disease. J. Neurosci., 21, RC143 1-6.
-
(2001)
J. Neurosci.
, vol.21
, pp. 1-6
-
-
Chen, J.-F.1
Xu, K.2
Petzer, J.P.3
Staal, R.4
Xu, Y.-H.5
Beilstein, M.6
Sonsalla, P.K.7
Castagnoli, K.8
Castagnoli, N.9
Schwarzschild, M.A.10
-
35
-
-
0025265926
-
The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
-
Choi, D.W. and Rothman, S.M. (1990) The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci., 13, 171-182.
-
(1990)
Annu. Rev. Neurosci.
, vol.13
, pp. 171-182
-
-
Choi, D.W.1
Rothman, S.M.2
-
36
-
-
0037179121
-
Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra
-
Chu, Y., Kompoliti, K., Cochran, E.J., Mufson, E.J., and Kordower, J.H. (2002) Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra. J. Comp. Neurol., 450, 203-14.
-
(2002)
J. Comp. Neurol.
, vol.450
, pp. 203-214
-
-
Chu, Y.1
Kompoliti, K.2
Cochran, E.J.3
Mufson, E.J.4
Kordower, J.H.5
-
37
-
-
0030995878
-
Pharmacology and functions of metabotropic glutamate receptors
-
Conn, P.J. and Pin, J.P. (1997) Pharmacology and functions of metabotropic glutamate receptors. Ann. Rev. Pharm. Tox., 37, 205-37.
-
(1997)
Ann. Rev. Pharm. Tox.
, vol.37
, pp. 205-237
-
-
Conn, P.J.1
Pin, J.P.2
-
38
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease
-
Conway, K.A., Harper, J.D., and Lansbury, P.T. (1998) Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease. Nat. Med., 4, 1318-20.
-
(1998)
Nat. Med.
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
39
-
-
0034528027
-
Accelerated oligomerization by Parkinson's disease linked alpha- synuclein mutants
-
Conway, K.A., Lee, S.J., Rochet, J.C., Ding, T.T., Harper, J.D., Williamson, R.E., and Lansbury, P.T., Jr. (2000) Accelerated oligomerization by Parkinson's disease linked alpha- synuclein mutants. Ann. NY Acad. Sci., 920, 42-5.
-
(2000)
Ann. NY Acad. Sci.
, vol.920
, pp. 42-45
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Harper, J.D.5
Williamson, R.E.6
Lansbury Jr., P.T.7
-
40
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
Conway, K.A., Lee, S.J., Rochet, J.C., Ding, T.T., Williamson, R.E., and Lansbury, P.T., Jr. (2000) Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proc. Natl. Acad. Sci. USA, 97, 571-6.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury Jr., P.T.6
-
41
-
-
0035834360
-
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine- alpha-synuclein adduct
-
Conway, K.A., Rochet, J.C., Bieganski, R.M., and Lansbury, P.T., Jr. (2001) Kinetic stabilization of the alpha-synuclein protofibril by a dopamine- alpha-synuclein adduct. Science, 294, 1346-9.
-
(2001)
Science
, vol.294
, pp. 1346-1349
-
-
Conway, K.A.1
Rochet, J.C.2
Bieganski, R.M.3
Lansbury Jr., P.T.4
-
42
-
-
0014673226
-
Modification of parkinsonism - Chronic treatment with L-DOPA
-
Cotzias, G.C., Papavasiliou, P.S., and Gellene, R. (1969) Modification of parkinsonism - chronic treatment with L-DOPA. New Eng. J. Med., 280, 337-345.
-
(1969)
New Eng. J. Med.
, vol.280
, pp. 337-345
-
-
Cotzias, G.C.1
Papavasiliou, P.S.2
Gellene, R.3
-
43
-
-
0031951010
-
Expression of N-methyl-D-aspartate receptor subunit mRNA in human mesencephalic dopamine neurons
-
Counihan, T.J., Landwehrmeyer, G.B., Standaert, D.G., Kosinski, C.M., Scherzer, C.R., Daggett, L.P., Velicelebi, G., Young, A.B., and Penney, J.B. (1998) Expression of N-methyl-D-aspartate receptor subunit mRNA in human mesencephalic dopamine neurons. J. Comp. Neurol., 390, 91-101.
-
(1998)
J. Comp. Neurol.
, vol.390
, pp. 91-101
-
-
Counihan, T.J.1
Landwehrmeyer, G.B.2
Standaert, D.G.3
Kosinski, C.M.4
Scherzer, C.R.5
Daggett, L.P.6
Velicelebi, G.7
Young, A.B.8
Penney, J.B.9
-
44
-
-
0034640011
-
Fourteen and counting: Unraveling trinucleotide repeat diseases
-
Cummings, C.J. and Zoghbi, H.Y. (2000) Fourteen and counting: unraveling trinucleotide repeat diseases. Hum. Mol. Genet., 9, 909-16.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 909-916
-
-
Cummings, C.J.1
Zoghbi, H.Y.2
-
45
-
-
0029951445
-
Does monoamine oxidase type B play a role in dopaminergic nerve cell death in Parkinson's disease?
-
Damier, P., Kastner, A., Agid, Y., and Hirsch, E.C. (1996) Does monoamine oxidase type B play a role in dopaminergic nerve cell death in Parkinson's disease? Neurology, 46, 1262-9.
-
(1996)
Neurology
, vol.46
, pp. 1262-1269
-
-
Damier, P.1
Kastner, A.2
Agid, Y.3
Hirsch, E.C.4
-
46
-
-
0036829946
-
Neuroprotective and neurorestorative strategies for Parkinson's disease
-
Dawson, T.M. and Dawson, V.L. (2002) Neuroprotective and neurorestorative strategies for Parkinson's disease. Nat. Neurosci., 5 Suppl., 1058-61.
-
(2002)
Nat. Neurosci.
, vol.5
, Issue.SUPPL.
, pp. 1058-1061
-
-
Dawson, T.M.1
Dawson, V.L.2
-
47
-
-
0030943863
-
Dietary antioxidants and Parkinson disease. The Rotterdam Study
-
de Rijk, M.C., Breteler, M.M., den Breeijen, J.H., Launer, L.J., Grobbee, D.E., van der Meche, F.G., and Hofman, A. (1997) Dietary antioxidants and Parkinson disease. The Rotterdam Study. Arch. Neurol., 54, 762-5.
-
(1997)
Arch. Neurol.
, vol.54
, pp. 762-765
-
-
de Rijk, M.C.1
Breteler, M.M.2
den Breeijen, J.H.3
Launer, L.J.4
Grobbee, D.E.5
van der Meche, F.G.6
Hofman, A.7
-
48
-
-
0038115294
-
Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice
-
Dedeoglu, A., Kubilus, J.K., Yang, L., Ferrante, K.L., Hersch, S.M., Beal, M.F., and Ferrante, R.J. (2003) Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice. J. Neurochem., 85, 1359-67.
-
(2003)
J. Neurochem.
, vol.85
, pp. 1359-1367
-
-
Dedeoglu, A.1
Kubilus, J.K.2
Yang, L.3
Ferrante, K.L.4
Hersch, S.M.5
Beal, M.F.6
Ferrante, R.J.7
-
49
-
-
0023638828
-
Increased nigral iron content in postmortem parkinsonian brain
-
Dexter, D.T., Wells, F.R., Agid, F., Agid, Y., Lees, A.J., Jenner, P., and Marsden, C.D. (1987) Increased nigral iron content in postmortem parkinsonian brain. Lancet, 2, 1219-20.
-
(1987)
Lancet
, vol.2
, pp. 1219-1220
-
-
Dexter, D.T.1
Wells, F.R.2
Agid, F.3
Agid, Y.4
Lees, A.J.5
Jenner, P.6
Marsden, C.D.7
-
50
-
-
0026694525
-
Glutathione in Parkinson's disease: A link between oxidative stress and mitochondrial damage?
-
Di Monte, D.A., Chan, P., and Sandy, M.S. (1992) Glutathione in Parkinson's disease: a link between oxidative stress and mitochondrial damage? Ann. Neurol., 32, S111-5.
-
(1992)
Ann. Neurol.
, vol.32
-
-
Di Monte, D.A.1
Chan, P.2
Sandy, M.S.3
-
51
-
-
0023226021
-
Multi-center study of parkinson mortality with early versus later dopa treatment
-
Diamond, S.G., Markham, C.H., Hoehn, M.M., McDowell, F.H., and Muenter, M.D. (1987) Multi-center study of parkinson mortality with early versus later dopa treatment. Ann. Neurol., 22, 8-12.
-
(1987)
Ann. Neurol.
, vol.22
, pp. 8-12
-
-
Diamond, S.G.1
Markham, C.H.2
Hoehn, M.M.3
McDowell, F.H.4
Muenter, M.D.5
-
52
-
-
0032833653
-
Widespread alterations of alpha-synuclein in multiple system atrophy
-
Dickson, D.W., Liu, W., Hardy, J., Farrer, M., Mehta, N., Uitti, R., Mark, M., Zimmerman, T., Golbe, L., Sage, J., Sima, A., D'Amato, C., Albin, R., Gilman, S., and Yen, S.H. (1999) Widespread alterations of alpha-synuclein in multiple system atrophy. Am. J. Pathol., 155, 1241-51.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1241-1251
-
-
Dickson, D.W.1
Liu, W.2
Hardy, J.3
Farrer, M.4
Mehta, N.5
Uitti, R.6
Mark, M.7
Zimmerman, T.8
Golbe, L.9
Sage, J.10
Sima, A.11
D'Amato, C.12
Albin, R.13
Gilman, S.14
Yen, S.H.15
-
53
-
-
0032912771
-
The glutamate receptor ion channels
-
Dingeldine, R., Borges, K., Bowie, D., and Traynelis, S.F. (1999) The glutamate receptor ion channels. Pharmacological Reviews, 51, 7-61.
-
(1999)
Pharmacological Reviews
, vol.51
, pp. 7-61
-
-
Dingeldine, R.1
Borges, K.2
Bowie, D.3
Traynelis, S.F.4
-
54
-
-
0027314268
-
Molecular profile of reactive astrocytes-implications for their role in neurologic disease
-
Eddleston, M. and Mucke, L. (1993) Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience, 54, 15-36.
-
(1993)
Neuroscience
, vol.54
, pp. 15-36
-
-
Eddleston, M.1
Mucke, L.2
-
55
-
-
0037225268
-
Survival study of Parkinson disease in Olmsted County, Minnesota
-
Elbaz, A., Bower, J.H., Peterson, B.J., Maraganore, D.M., McDonnell, S.K., Ahlskog, J.E., Schaid, D.J., and Rocca, W.A. (2003) Survival study of Parkinson disease in Olmsted County, Minnesota. Arch. Neurol., 60, 91-6.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 91-96
-
-
Elbaz, A.1
Bower, J.H.2
Peterson, B.J.3
Maraganore, D.M.4
McDonnell, S.K.5
Ahlskog, J.E.6
Schaid, D.J.7
Rocca, W.A.8
-
56
-
-
0026079083
-
An open trial of high-dosage antioxidants in early Parkinson's disease
-
Fahn, S. (1991) An open trial of high-dosage antioxidants in early Parkinson's disease. Am. J. Clin. Nutr., 53, 380S-382S.
-
(1991)
Am. J. Clin. Nutr.
, vol.53
-
-
Fahn, S.1
-
57
-
-
0026636491
-
A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease
-
Fahn, S. (1992) A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease. Ann. Neurol., 32 Suppl., S128-32.
-
(1992)
Ann. Neurol.
, vol.32
, Issue.SUPPL.
-
-
Fahn, S.1
-
58
-
-
0026764766
-
Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration
-
Favit, A., Nicoletti, F., Scapagnihi, U., and Canonico, P.L. (1992) Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration. J. Cereb. Blood Flow Metab., 12, 638-45.
-
(1992)
J. Cereb. Blood Flow Metab.
, vol.12
, pp. 638-645
-
-
Favit, A.1
Nicoletti, F.2
Scapagnihi, U.3
Canonico, P.L.4
-
59
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany, M.B. and Bender, W.W. (2000) A Drosophila model of Parkinson's disease. Nature, 404, 394-8.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
60
-
-
0002724965
-
Pathology of Parkinson's disease
-
Caine, D.B., Editor W.B. Saunders: Philadelphia
-
Fearnley, J. and Lees, A.(1994) Pathology of Parkinson's disease, In: Caine, D.B., Editor Neurodegenerative Diseases, W.B. Saunders: Philadelphia. pp. 545-571.
-
(1994)
Neurodegenerative Diseases
, pp. 545-571
-
-
Fearnley, J.1
Lees, A.2
-
61
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Ferrante, R.J., Browne, S.E., Shinobu, L.A., Bowling, A.C., Baik, M.J., MacGarvey, U., Kowall, N.W., Brown, R.H. Jr., and Beal, M.F. (1997) Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J. Neurochem., 69, 2064-74.
-
(1997)
J. Neurochem.
, vol.69
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
MacGarvey, U.6
Kowall, N.W.7
Brown Jr., R.H.8
Beal, M.F.9
-
62
-
-
0027140986
-
The striatopallidal neuron: A main locus for adenosine -dopamine interactions in the brain
-
Ferré, S., O'Connor, W.T., Fuxe, K., and Ungerstedt, U. (1993) The striatopallidal neuron: a main locus for adenosine -dopamine interactions in the brain. J. Neurosci., 13, 5402-5406.
-
(1993)
J. Neurosci.
, vol.13
, pp. 5402-5406
-
-
Ferré, S.1
O'Connor, W.T.2
Fuxe, K.3
Ungerstedt, U.4
-
63
-
-
0035668350
-
Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies
-
Ferrer, I., Blanca, R., Carmona, M., Puig, B., Barrachina, M., Gomez, C., and Ambrosio, S. (2001) Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies. J. Neural. Transm., 108, 1383-96.
-
(2001)
J. Neural. Transm.
, vol.108
, pp. 1383-1396
-
-
Ferrer, I.1
Blanca, R.2
Carmona, M.3
Puig, B.4
Barrachina, M.5
Gomez, C.6
Ambrosio, S.7
-
64
-
-
0036914093
-
Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours
-
Finberg, J.P. and Youdim, M.B. (2002) Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours. Neuropharmacol., 43, 1110-8.
-
(2002)
Neuropharmacol.
, vol.43
, pp. 1110-1118
-
-
Finberg, J.P.1
Youdim, M.B.2
-
65
-
-
0036100765
-
Parkinson syndrome as a manifestation of mitochondriopathy
-
Finsterer, J. (2002) Parkinson syndrome as a manifestation of mitochondriopathy. Acta. Neurol. Scand., 105, 384-9.
-
(2002)
Acta. Neurol. Scand.
, vol.105
, pp. 384-389
-
-
Finsterer, J.1
-
66
-
-
0036786860
-
The genetic basis of Parkinson's disease
-
Foltynie, T., Sawcer, S., Brayne, C., and Barker, R.A. (2002) The genetic basis of Parkinson's disease. J. Neurol. Neurosurg. Psychiatry, 73, 363-70.
-
(2002)
J. Neurol. Neurosurg. Psychiatry
, vol.73
, pp. 363-370
-
-
Foltynie, T.1
Sawcer, S.2
Brayne, C.3
Barker, R.A.4
-
67
-
-
0029858229
-
A role for astrocytes in glucose delivery to neurons?
-
Forsyth, R., Fray, A., Boutelle, M., Fillenz, M., Middleditch, C., and Burchell, A. (1996) A role for astrocytes in glucose delivery to neurons? Dev. Neurosci., 18, 360-70.
-
(1996)
Dev. Neurosci.
, vol.18
, pp. 360-370
-
-
Forsyth, R.1
Fray, A.2
Boutelle, M.3
Fillenz, M.4
Middleditch, C.5
Burchell, A.6
-
68
-
-
0037231224
-
Monoamine oxidase and cigarette smoking
-
Fowler, J.S., Logan, J., Wang, G.J., and Volkow, N.D. (2003) Monoamine oxidase and cigarette smoking. Neurotoxicology, 24, 75-82.
-
(2003)
Neurotoxicology
, vol.24
, pp. 75-82
-
-
Fowler, J.S.1
Logan, J.2
Wang, G.J.3
Volkow, N.D.4
-
69
-
-
12644314144
-
Brain monoamine oxidase A inhibition in cigarette smokers
-
Fowler, J.S., Volkow, N.D., Wang, G.J., Pappas, N., Logan, J., Shea, C., Alexoff, D., MacGregor, R.R., Schlyer, D.J., Zezulkova, I., and Wolf, A.P. (1996) Brain monoamine oxidase A inhibition in cigarette smokers. Proc. Natl. Acad. Sci. USA, 93, 14065-9.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14065-14069
-
-
Fowler, J.S.1
Volkow, N.D.2
Wang, G.J.3
Pappas, N.4
Logan, J.5
Shea, C.6
Alexoff, D.7
MacGregor, R.R.8
Schlyer, D.J.9
Zezulkova, I.10
Wolf, A.P.11
-
70
-
-
0031662603
-
Neuroprotective and neurorestorative properties of GDNF
-
Gash, D.M., Zhang, Z., and Gerhardt, G. (1998) Neuroprotective and neurorestorative properties of GDNF. Ann. Neurol., 44, S121-5.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Gash, D.M.1
Zhang, Z.2
Gerhardt, G.3
-
71
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson, B.I., Duda, J.E., Quinn, S.M., Zhang, B., Trojanowski, J.Q., and Lee, V.M. (2002) Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron, 34, 521-33.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
72
-
-
0035959931
-
Parkin and the molecular pathways of Parkinson's disease
-
Giasson, B.I. and Lee, V.M. (2001) Parkin and the molecular pathways of Parkinson's disease. Neuron, 31, 885-8.
-
(2001)
Neuron
, vol.31
, pp. 885-888
-
-
Giasson, B.I.1
Lee, V.M.2
-
73
-
-
0026525526
-
Neuropathology of Parkinson's disease and related syndromes
-
Gibb, W.R. (1992) Neuropathology of Parkinson's disease and related syndromes. Neurol. Clin., 10, 361-76.
-
(1992)
Neurol. Clin.
, vol.10
, pp. 361-376
-
-
Gibb, W.R.1
-
74
-
-
0025763177
-
Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease
-
Gibb, W.R. and Lees, A.J. (1991) Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease. J. Neurol. Neurosurg. Psychiatry. 54, 388-96.
-
(1991)
J. Neurol. Neurosurg. Psychiatry
, vol.54
, pp. 388-396
-
-
Gibb, W.R.1
Lees, A.J.2
-
75
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill, S.S., Patel, N.K., Horton, G.R., O'Sullivan, K., McCarter, R., Bunnage, M., Brooks, D.J., Svendsen, C.N., and Heywood, P. (2003) Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat. Med., 9, 589-95.
-
(2003)
Nat. Med.
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Horton, G.R.3
O'Sullivan, K.4
McCarter, R.5
Bunnage, M.6
Brooks, D.J.7
Svendsen, C.N.8
Heywood, P.9
-
76
-
-
0033614777
-
Filamentous nerve cell inclusions in neurodegenerative diseases: Tauopathies and alpha-synucleinopathies
-
Goedert, M. (1999) Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies. Philos. Trans. R Soc. Land. B Biol. Sci., 354, 1101-18.
-
(1999)
Philos. Trans. R Soc. Land. B Biol. Sci.
, vol.354
, pp. 1101-1118
-
-
Goedert, M.1
-
77
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
Goedert, M. (2001) Alpha-synuclein and neurodegenerative diseases. Nat. Rev. Neurosci., 2, 492-501.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
78
-
-
0023724071
-
Case-control study of early life dietary factors in Parkinson's disease
-
Golbe, L.I., Farrell, T.M., and Davis, P.H. (1988) Case-control study of early life dietary factors in Parkinson's disease. Arch. Neurol., 45, 1350-3.
-
(1988)
Arch. Neurol.
, vol.45
, pp. 1350-1353
-
-
Golbe, L.I.1
Farrell, T.M.2
Davis, P.H.3
-
79
-
-
0025273787
-
Follow-up study of early-life protective and risk factors in Parkinson's disease
-
Golbe, L.I., Farrell, T.M., and Davis, P.H. (1990) Follow-up study of early-life protective and risk factors in Parkinson's disease. Mov. Disord., 5, 66-70.
-
(1990)
Mov. Disord.
, vol.5
, pp. 66-70
-
-
Golbe, L.I.1
Farrell, T.M.2
Davis, P.H.3
-
80
-
-
0033771793
-
Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?
-
Goldberg, M.S. and Lansbury, P.T., Jr. (2000) Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease? Nat. Cell Biol., 2, E115-9.
-
(2000)
Nat. Cell Biol.
, vol.2
-
-
Goldberg, M.S.1
Lansbury Jr., P.T.2
-
81
-
-
0034531645
-
Clinical and neuropathological correlates of dementia with Lewy bodies
-
Gomez-Tortosa, E., Irizarry, M.C., Gomez-Isla, T., and Hyman, B.T. (2000) Clinical and neuropathological correlates of dementia with Lewy bodies. Ann. N Y Acad. Sci., 920, 9-15.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.920
, pp. 9-15
-
-
Gomez-Tortosa, E.1
Irizarry, M.C.2
Gomez-Isla, T.3
Hyman, B.T.4
-
82
-
-
0034050672
-
MPTP and 6-hydroxydopamine-induced neurodegeneration as models for Parkinson's disease: Neuroprotective strategies
-
Grunblatt, E., Mandel, S., and Youdim, M.B. (2000) MPTP and 6-hydroxydopamine-induced neurodegeneration as models for Parkinson's disease: neuroprotective strategies. J. Neurol., 247 Suppl. 2, II95-102.
-
(2000)
J. Neurol.
, vol.247
, Issue.SUPPL. 2
-
-
Grunblatt, E.1
Mandel, S.2
Youdim, M.B.3
-
83
-
-
0036654314
-
Genetics of parkinsonism
-
Gwinn-Hardy, K. (2002) Genetics of parkinsonism. Mov. Disord., 17, 645-56.
-
(2002)
Mov. Disord.
, vol.17
, pp. 645-656
-
-
Gwinn-Hardy, K.1
-
84
-
-
0030566729
-
Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons
-
Hall, E.D., Andrus, P.K., Oostveen, J.A., Althaus, J.S., and VonVoigtlander, P.F. (1996) Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons. Brain Res., 742, 80-8.
-
(1996)
Brain Res.
, vol.742
, pp. 80-88
-
-
Hall, E.D.1
Andrus, P.K.2
Oostveen, J.A.3
Althaus, J.S.4
VonVoigtlander, P.F.5
-
85
-
-
0029759598
-
Reactive dopamine metabolites and neurotoxicity: Implications for Parkinson's disease
-
Hastings, T.G., Lewis, D.A., and Zigmond, M.J. (1996) Reactive dopamine metabolites and neurotoxicity: implications for Parkinson's disease. Adv. Exp. Med. Biol., 387, 97-106.
-
(1996)
Adv. Exp. Med. Biol.
, vol.387
, pp. 97-106
-
-
Hastings, T.G.1
Lewis, D.A.2
Zigmond, M.J.3
-
86
-
-
0043126954
-
Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD
-
Hauser, R.A., Hubble, J.P., and Truong, D.D. (2003) Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD. Neurology, 61, 297-303.
-
(2003)
Neurology
, vol.61
, pp. 297-303
-
-
Hauser, R.A.1
Hubble, J.P.2
Truong, D.D.3
-
87
-
-
0027055332
-
Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts
-
Hayakawa, M., Hattori, K., Sugiyama, S., and Ozawa, T. (1992) Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem. Biophys. Res. Commun., 189, 979-85.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, pp. 979-985
-
-
Hayakawa, M.1
Hattori, K.2
Sugiyama, S.3
Ozawa, T.4
-
88
-
-
0035800589
-
Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum
-
He, Y., Appel, S., and Le, W. (2001) Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res., 909, 187-93.
-
(2001)
Brain Res.
, vol.909
, pp. 187-193
-
-
He, Y.1
Appel, S.2
Le, W.3
-
89
-
-
9544227379
-
Diet and Parkinson's disease. II: A possible role for the past intake of specific nutrients. Results from a self-administered food-frequency questionnaire in a case-control study
-
Hellenbrand, W., Boeing, H., Robra, B.P., Seidler, A., Vieregge, P., Nischan, P., Joerg, J., Oertel, W.H., Schneider, E., and Ulm, G. (1996) Diet and Parkinson's disease. II: A possible role for the past intake of specific nutrients. Results from a self-administered food-frequency questionnaire in a case-control study. Neurology, 47, 644-50.
-
(1996)
Neurology
, vol.47
, pp. 644-650
-
-
Hellenbrand, W.1
Boeing, H.2
Robra, B.P.3
Seidler, A.4
Vieregge, P.5
Nischan, P.6
Joerg, J.7
Oertel, W.H.8
Schneider, E.9
Ulm, G.10
-
90
-
-
9544242732
-
Diet and Parkinson's disease. I: A possible role for the past intake of specific foods and food groups. Results from a self-administered food-frequency questionnaire in a case-control study
-
Hellenbrand, W., Seidler, A., Boeing, H., Robra, B.P., Vieregge, P., Nischan, P., Joerg, J., Oertel, W.H., Schneider, E., and Ulm, G. (1996) Diet and Parkinson's disease. I: A possible role for the past intake of specific foods and food groups. Results from a self-administered food-frequency questionnaire in a case-control study. Neurology, 47, 636-43.
-
(1996)
Neurology
, vol.47
, pp. 636-643
-
-
Hellenbrand, W.1
Seidler, A.2
Boeing, H.3
Robra, B.P.4
Vieregge, P.5
Nischan, P.6
Joerg, J.7
Oertel, W.H.8
Schneider, E.9
Ulm, G.10
-
91
-
-
0036714747
-
A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease
-
Hernan, M.A., Takkouche, B., Caamano-Isorna, F., and Gestal-Otero, J.J. (2002) A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease. Ann. Neurol., 52, 276-84.
-
(2002)
Ann. Neurol.
, vol.52
, pp. 276-284
-
-
Hernan, M.A.1
Takkouche, B.2
Caamano-Isorna, F.3
Gestal-Otero, J.J.4
-
92
-
-
0034052904
-
Glial cells and Parkinson's disease
-
Hirsch, E.C. (2000) Glial cells and Parkinson's disease. J. Neurol., 247 Suppl .2, II58-62.
-
(2000)
J. Neurol.
, vol.247
, Issue.SUPPL. 2
-
-
Hirsch, E.C.1
-
93
-
-
18144447904
-
Glial cell participation in the degeneration of dopaminergic neurons in Parkinson's disease
-
Hirsch, E.C., Hunot, S., Damier, P., Brugg, B., Faucheux, B.A., Michel, P.P., Ruberg, M., Muriel, M.P., Mouatt-Prigent, A., and Agid, Y. (1999) Glial cell participation in the degeneration of dopaminergic neurons in Parkinson's disease. Adv. Neurol., 80, 9-18.
-
(1999)
Adv. Neurol.
, vol.80
, pp. 9-18
-
-
Hirsch, E.C.1
Hunot, S.2
Damier, P.3
Brugg, B.4
Faucheux, B.A.5
Michel, P.P.6
Ruberg, M.7
Muriel, M.P.8
Mouatt-Prigent, A.9
Agid, Y.10
-
94
-
-
0031715925
-
Glial cells and inflammation in Parkinson's disease: A role in neurodegeneration?
-
Hirsch, E.C., Hunot, S., Damier, P., and Faucheux, B. (1998) Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration? Ann. Neurol., 44, S115-20.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Hirsch, E.C.1
Hunot, S.2
Damier, P.3
Faucheux, B.4
-
95
-
-
0015626895
-
Dopamine in the basal ganglia
-
Hornykiewicz, O. (1973) Dopamine in the basal ganglia. Br. Med. Bull., 29, 172-178.
-
(1973)
Br. Med. Bull.
, vol.29
, pp. 172-178
-
-
Hornykiewicz, O.1
-
96
-
-
0036589897
-
Dopamine miracle: From brain homogenate to dopamine replacement
-
Hornykiewicz, O. (2002) Dopamine miracle: From brain homogenate to dopamine replacement. Mov. Disord., 17, 501-8.
-
(2002)
Mov. Disord.
, vol.17
, pp. 501-508
-
-
Hornykiewicz, O.1
-
97
-
-
0027500761
-
Risk factors for Parkinson's disease
-
Hubble, J.P., Cao, T., Hassanein, R.E., Neuberger, J.S., and Koller, W.C. (1993) Risk factors for Parkinson's disease. Neurology, 43, 1693-7.
-
(1993)
Neurology
, vol.43
, pp. 1693-1697
-
-
Hubble, J.P.1
Cao, T.2
Hassanein, R.E.3
Neuberger, J.S.4
Koller, W.C.5
-
98
-
-
0344235786
-
Immunohistochemical analysis of Intereferon-(gamma) and interleukin1-beta in the substantia nigra of Parkinsonian patients
-
Hunot, S., Betard, C., Faucheaux, B., Agid, Y., and Hirsch, E.C. (1997) Immunohistochemical analysis of Intereferon-(gamma) and interleukin1-beta in the substantia nigra of Parkinsonian patients. Mov. Disord., 12, 20.
-
(1997)
Mov. Disord.
, vol.12
, pp. 20
-
-
Hunot, S.1
Betard, C.2
Faucheaux, B.3
Agid, Y.4
Hirsch, E.C.5
-
99
-
-
0343844458
-
Nitric oxide synthase and neuronal vulnerability in Parkinson's disease
-
Hunot, S., Boissiere, F., Faucheux, B., Brugg, B., Mouatt-Prigent, A., Agid, Y., and Hirsch, E.C. (1996) Nitric oxide synthase and neuronal vulnerability in Parkinson's disease. Neuroscience, 72, 355-63.
-
(1996)
Neuroscience
, vol.72
, pp. 355-363
-
-
Hunot, S.1
Boissiere, F.2
Faucheux, B.3
Brugg, B.4
Mouatt-Prigent, A.5
Agid, Y.6
Hirsch, E.C.7
-
100
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group
-
Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell, 72, 971-83.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
101
-
-
0034758936
-
Prospects for the treatment of Parkinson's disease using neurotrophic factors
-
Hurelbrink, C.B. and Barker, R.A. (2001) Prospects for the treatment of Parkinson's disease using neurotrophic factors. Expert Opin. Pharmacother., 2, 1531-43.
-
(2001)
Expert Opin. Pharmacother.
, vol.2
, pp. 1531-1543
-
-
Hurelbrink, C.B.1
Barker, R.A.2
-
102
-
-
0031944830
-
Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha- synuclein immunoreactivity
-
Irizarry, M.C., Growdon, W., Gomez-Isla, T., Newell, K., George, J.M., Clayton, D.F., and Hyman, B.T. (1998) Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha- synuclein immunoreactivity. J. Neuropathol. Exp. Neurol., 57, 334-7.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 334-337
-
-
Irizarry, M.C.1
Growdon, W.2
Gomez-Isla, T.3
Newell, K.4
George, J.M.5
Clayton, D.F.6
Hyman, B.T.7
-
103
-
-
0033955608
-
Cell death mechanisms in Parkinson's disease
-
Jellinger, K.A. (2000) Cell death mechanisms in Parkinson's disease. J. Neural. Transm., 107, 1-29.
-
(2000)
J. Neural. Transm.
, vol.107
, pp. 1-29
-
-
Jellinger, K.A.1
-
104
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
discussion S36-8
-
Jenner, P. (2003) Oxidative stress in Parkinson's disease. Ann. Neurol., 53 Suppl. 3, S26-36; discussion S36-8.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Jenner, P.1
-
105
-
-
0029751104
-
Oxidative stress and the pathogenesis of Parkinson's disease
-
Jenner, P. and Olanow, C.W. (1996) Oxidative stress and the pathogenesis of Parkinson's disease. Neurology, 47, S161-70.
-
(1996)
Neurology
, vol.47
-
-
Jenner, P.1
Olanow, C.W.2
-
106
-
-
0036229267
-
Role of parkin mutations in 111 community-based patients with early- onset parkinsonism
-
Kann, M., Jacobs, H., Mohrmann, K., Schumacher, K., Hedrich, K., Garrels, J., Wiegers, K., Schwinger, E., Pramstaller, P.P., Breakefield, X.O., Ozelius, L.J., Vieregge, P., and Klein, C. (2002) Role of parkin mutations in 111 community-based patients with early- onset parkinsonism. Ann. Neurol., 51, 621-5.
-
(2002)
Ann. Neurol.
, vol.51
, pp. 621-625
-
-
Kann, M.1
Jacobs, H.2
Mohrmann, K.3
Schumacher, K.4
Hedrich, K.5
Garrels, J.6
Wiegers, K.7
Schwinger, E.8
Pramstaller, P.P.9
Breakefield, X.O.10
Ozelius, L.J.11
Vieregge, P.12
Klein, C.13
-
107
-
-
0031469841
-
Analysis of a form of oxidative DNA damage, 8-hydroxy-2′- deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
-
Kasai, H. (1997) Analysis of a form of oxidative DNA damage, 8-hydroxy-2′- deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat. Res., 387, 147-63.
-
(1997)
Mutat. Res.
, vol.387
, pp. 147-163
-
-
Kasai, H.1
-
108
-
-
0037378736
-
Designing neuroprotection trials in Parkinson's disease
-
discussion S107-9
-
Kieburtz, K. (2003) Designing neuroprotection trials in Parkinson's disease. Ann. Neurol., 53 Suppl. 3, S100-7; discussion S107-9.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Kieburtz, K.1
-
109
-
-
0031738971
-
DNA fragmentation in human substantia nigra: Apoptosis or perimortem effect?
-
Kingsbury, A.E., Mardsen, C.D., and Foster, O.J. (1998) DNA fragmentation in human substantia nigra: apoptosis or perimortem effect? Mov. Disord., 13, 877-84.
-
(1998)
Mov. Disord.
, vol.13
, pp. 877-884
-
-
Kingsbury, A.E.1
Mardsen, C.D.2
Foster, O.J.3
-
110
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y., and Shimizu, N. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature, 329, 605-608.
-
(1998)
Nature
, vol.329
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
111
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
Klivenyi, P., Ferrante, R.J., Matthews, R.T., Bogdanov, M.B., Klein, A.M., Andreassen, O.A., Mueller, G., Wermer, M., Kaddurah-Daouk, R., and Beal, M.F. (1999) Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat. Med., 5, 347-50.
-
(1999)
Nat. Med.
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
Mueller, G.7
Wermer, M.8
Kaddurah-Daouk, R.9
Beal, M.F.10
-
112
-
-
0034520395
-
Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2
-
Knott, C., Stern, G., and Wilkin, G.P. (2000) Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2. Mol Cell Neurosci., 16, 724-39.
-
(2000)
Mol. Cell Neurosci.
, vol.16
, pp. 724-739
-
-
Knott, C.1
Stern, G.2
Wilkin, G.P.3
-
113
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower, J.H., Emborg, M.E., Bloch, J., Ma, S.Y., Chu, Y., Leventhal, L., McBride, J., Chen, E.Y., Palfi, S., Roitberg, B.Z., Brown, W.D., Holden, J.E., Pyzalski, R., Taylor, M.D., Carvey, P., Ling, Z., Trono, D., Hantraye, P., Deglon, N., and Aebischer, P. (2000) Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science, 290, 767-73.
-
(2000)
Science
, vol.290
, pp. 767-773
-
-
Kordower, J.H.1
Emborg, M.E.2
Bloch, J.3
Ma, S.Y.4
Chu, Y.5
Leventhal, L.6
McBride, J.7
Chen, E.Y.8
Palfi, S.9
Roitberg, B.Z.10
Brown, W.D.11
Holden, J.E.12
Pyzalski, R.13
Taylor, M.D.14
Carvey, P.15
Ling, Z.16
Trono, D.17
Hantraye, P.18
Deglon, N.19
Aebischer, P.20
more..
-
114
-
-
0030222037
-
Microglia: A sensor for pathological events in the CNS
-
Kreutzberg, G.W. (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci., 19, 312-8.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
115
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J.T., Schols, L., and Riess, O. (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet., 18, 106-8.
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
116
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang, A.E. and Lozano, A.M. (1998) Parkinson's disease. First of two parts. N. Engl. J. Med., 339, 1044-53.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
117
-
-
0032531924
-
Parkinson's disease. Second of two parts
-
Lang, A.E. and Lozano, A.M. (1998) Parkinson's disease. Second of two parts. N. Engl. J. Med., 339, 1130-43.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1130-1143
-
-
Lang, A.E.1
Lozano, A.M.2
-
118
-
-
0028170915
-
Neuroprotection by dopamine agonists
-
Lange, K.W., Rausch, W.D., Gsell, W., Naumann, M., Oestreicher, E., and Riederer, P. (1994) Neuroprotection by dopamine agonists. J. Neural. Transm. Suppl., 43, 183-201.
-
(1994)
J. Neural. Transm. Suppl.
, vol.43
, pp. 183-201
-
-
Lange, K.W.1
Rausch, W.D.2
Gsell, W.3
Naumann, M.4
Oestreicher, E.5
Riederer, P.6
-
119
-
-
0029751103
-
The etiology of Parkinson's disease with emphasis on the MPTP story
-
Langston, J.W. (1996) The etiology of Parkinson's disease with emphasis on the MPTP story. Neurology, 47, S153-60.
-
(1996)
Neurology
, vol.47
-
-
Langston, J.W.1
-
120
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston, J.W., Ballard, P., Tetrud, J.W., and Irwin, I. (1983) Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science, 219, 979-80.
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
121
-
-
17644436692
-
Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype
-
Lin, F.F., Varney, M., Sacaan, A.I., Jachec, C., Daggett, L.P., Rao, S., Flor, P., Kuhn, R., Kerner, J.A., Standaert, D., Young, A.B., and Velicelebi, G. (1997) Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype. Neuropharmacol., 36, 917-31.
-
(1997)
Neuropharmacol.
, vol.36
, pp. 917-931
-
-
Lin, F.F.1
Varney, M.2
Sacaan, A.I.3
Jachec, C.4
Daggett, L.P.5
Rao, S.6
Flor, P.7
Kuhn, R.8
Kerner, J.A.9
Standaert, D.10
Young, A.B.11
Velicelebi, G.12
-
122
-
-
0037081814
-
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
-
Lin, M.T., Simon, D.K., Ahn, C.H., Kim, L.M., and Beal, M.F. (2002) High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Hum. Mol. Genet., 11, 133-45.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 133-145
-
-
Lin, M.T.1
Simon, D.K.2
Ahn, C.H.3
Kim, L.M.4
Beal, M.F.5
-
123
-
-
0030878320
-
Environmental risk factors and Parkinson's disease: A case-control study in Taiwan
-
Liou, H.H., Tsai, M.C., Chen, C.J., Jeng, J.S., Chang, Y.C., Chen, S.Y., and Chen, R.C. (1997) Environmental risk factors and Parkinson's disease: a case-control study in Taiwan. Neurology, 48, 1583-8.
-
(1997)
Neurology
, vol.48
, pp. 1583-1588
-
-
Liou, H.H.1
Tsai, M.C.2
Chen, C.J.3
Jeng, J.S.4
Chang, Y.C.5
Chen, S.Y.6
Chen, R.C.7
-
124
-
-
0030051986
-
Dietary lipids and antioxidants in Parkinson's disease: A population-based, case-control study
-
Logroscino, G., Marder, K., Cote, L., Tang, M.X., Shea, S., and Mayeux, R. (1996) Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study. Ann. Neurol., 39, 89-94.
-
(1996)
Ann. Neurol.
, vol.39
, pp. 89-94
-
-
Logroscino, G.1
Marder, K.2
Cote, L.3
Tang, M.X.4
Shea, S.5
Mayeux, R.6
-
125
-
-
0027233049
-
Glial-neuronal interactions: Relevance to neurotoxic mechanisms
-
LoPachin, R.M., Jr. and Aschner, M. (1993) Glial-neuronal interactions: relevance to neurotoxic mechanisms. Toxicol. Appl. Pharmacol., 118, 141-58.
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.118
, pp. 141-158
-
-
LoPachin Jr., R.M.1
Aschner, M.2
-
126
-
-
0033626282
-
Beneficial effects of amantadine on L-dopa-induced dyskinesias in Parkinson's disease
-
Luginger, E., Wenning, G.K., Bosch, S., and Poewe, W. (2000) Beneficial effects of amantadine on L-dopa-induced dyskinesias in Parkinson's disease. Mov. Disord., 15, 873-8.
-
(2000)
Mov. Disord.
, vol.15
, pp. 873-878
-
-
Luginger, E.1
Wenning, G.K.2
Bosch, S.3
Poewe, W.4
-
127
-
-
0036179194
-
Excitotoxicity: Perspectives based on N-methyl-D-aspartate receptor subtypes
-
Lynch, D.R. and Guttmann, R.P. (2002) Excitotoxicity: perspectives based on N-methyl-D-aspartate receptor subtypes. J. Pharmacol. Exp. Ther., 300, 717-23.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 717-723
-
-
Lynch, D.R.1
Guttmann, R.P.2
-
128
-
-
0029942825
-
Cellular mechanisms of brain energy metabolism. Relevance to functional brain imaging and to neurodegenerative disorders
-
Magistretti, P.J. and Pellerin, L. (1996) Cellular mechanisms of brain energy metabolism. Relevance to functional brain imaging and to neurodegenerative disorders. Ann. NY Acad. Sci., 777, 380-7.
-
(1996)
Ann. NY Acad. Sci.
, vol.777
, pp. 380-387
-
-
Magistretti, P.J.1
Pellerin, L.2
-
129
-
-
0034737380
-
Neuroprotective effects of creative administration against NMDA and malonate toxicity
-
Malcon, C., Kaddurah-Daouk, R., and Beal, M.F. (2000) Neuroprotective effects of creative administration against NMDA and malonate toxicity. Brain Res., 860, 195-8.
-
(2000)
Brain Res.
, vol.860
, pp. 195-198
-
-
Malcon, C.1
Kaddurah-Daouk, R.2
Beal, M.F.3
-
130
-
-
0037127197
-
The herbicide paraquat causes up-regulation and aggregation of alpha- synuclein in mice: Paraquat and alpha-synuclein
-
Manning-Bog, A.B., McCormack, A.L., Li, J., Uversky, V.N., Fink, A.L., and Di Monte, D.A. (2002) The herbicide paraquat causes up-regulation and aggregation of alpha- synuclein in mice: paraquat and alpha-synuclein. J. Biol. Chem., 277, 1641-4.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1641-1644
-
-
Manning-Bog, A.B.1
McCormack, A.L.2
Li, J.3
Uversky, V.N.4
Fink, A.L.5
Di Monte, D.A.6
-
131
-
-
0035846468
-
[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression
-
Marek, K., Innis, R., van Dyck, C., Fussell, B., Early, M., Eberly, S., Oakes, D., and Seibyl, J. (2001) [123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression. Neurology, 57, 2089-94.
-
(2001)
Neurology
, vol.57
, pp. 2089-2094
-
-
Marek, K.1
Innis, R.2
van Dyck, C.3
Fussell, B.4
Early, M.5
Eberly, S.6
Oakes, D.7
Seibyl, J.8
-
132
-
-
0037378851
-
Dopamine agonists and Parkinson's disease progression: What can we learn from neuroimaging studies
-
discussion S166-9
-
Marek, K., Jennings, D., and Seibyl, J. (2003) Dopamine agonists and Parkinson's disease progression: what can we learn from neuroimaging studies. Ann. Neurol., 53 Suppl. 3, S160-6; discussion S166-9.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Marek, K.1
Jennings, D.2
Seibyl, J.3
-
133
-
-
0042733062
-
Anti-inflammatory drugs and Alzheimer's disease
-
Martyn, C. (2003) Anti-inflammatory drugs and Alzheimer's disease. Brit. Med. J., 327, 353-4.
-
(2003)
Brit. Med. J.
, vol.327
, pp. 353-354
-
-
Martyn, C.1
-
134
-
-
0034738387
-
Mechanism underlying anti-apoptotic activity of a (-)deprenyl-related propargylamine, rasagiline
-
Maruyama, W., Yamamoto, T., Kitani, K., Carrillo, M.C., Youdim, M., and Naoi, M. (2000) Mechanism underlying anti-apoptotic activity of a (-)deprenyl-related propargylamine, rasagiline. Mech Ageing Dev., 116, 181-91.
-
(2000)
Mech Ageing Dev.
, vol.116
, pp. 181-191
-
-
Maruyama, W.1
Yamamoto, T.2
Kitani, K.3
Carrillo, M.C.4
Youdim, M.5
Naoi, M.6
-
135
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in alpha synuclein mice: Implications for neurodegenerative disorders
-
Masliah, E., Rockenstein, E., Veinbergs, I., Mallory, M., Hashimoto, M., Takeda, A., Sagara, Y., Sisk, A., and Mucke, L. (2000) Dopaminergic loss and inclusion body formation in alpha synuclein mice: implications for neurodegenerative disorders. Science, 287, 1265-9.
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
136
-
-
0028969650
-
Prostaglandin H synthetase-mediated metabolism of dopamine: Implication for Parkinson's disease
-
Mattammal, M.B., Strong, R., Lakshmi, V.M., Chung, H.D., and Stephenson, A.H. (1995) Prostaglandin H synthetase-mediated metabolism of dopamine: implication for Parkinson's disease. J. Neurochem., 64, 1645-54.
-
(1995)
J. Neurochem.
, vol.64
, pp. 1645-1654
-
-
Mattammal, M.B.1
Strong, R.2
Lakshmi, V.M.3
Chung, H.D.4
Stephenson, A.H.5
-
137
-
-
0032914740
-
Creative and cyclocreatine attenuate MPTP neurotoxicity
-
Matthews, R.T., Ferrante, R.J., Klivenyi, P., Yang, L., Klein, A.M., Mueller, G., Kaddurah-Daouk, R., and Beal, M.F. (1999) Creative and cyclocreatine attenuate MPTP neurotoxicity. Exp. Neurol., 157, 142-9.
-
(1999)
Exp. Neurol.
, vol.157
, pp. 142-149
-
-
Matthews, R.T.1
Ferrante, R.J.2
Klivenyi, P.3
Yang, L.4
Klein, A.M.5
Mueller, G.6
Kaddurah-Daouk, R.7
Beal, M.F.8
-
138
-
-
0043180531
-
Excitotoxic and excitoprotective mechanisms: Abundant targets for the prevention and treatment of neurodegenerative disorders
-
Mattson, M.P. (2003) Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromolecular Med., 3, 65-94.
-
(2003)
Neuromolecular Med.
, vol.3
, pp. 65-94
-
-
Mattson, M.P.1
-
139
-
-
0028152717
-
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
-
Mecocci, P., MacGarvey, U., and Beal, M.F. (1994) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol., 36, 747-51.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 747-751
-
-
Mecocci, P.1
MacGarvey, U.2
Beal, M.F.3
-
140
-
-
0027527023
-
Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain
-
Mecocci, P., MacGarvey, U., Kaufman, A.E., Koontz, D., Shoffner, J.M., Wallace, D.C., and Beal, M.F. (1993) Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann. Neurol., 34, 609-16.
-
(1993)
Ann. Neurol.
, vol.34
, pp. 609-616
-
-
Mecocci, P.1
MacGarvey, U.2
Kaufman, A.E.3
Koontz, D.4
Shoffner, J.M.5
Wallace, D.C.6
Beal, M.F.7
-
141
-
-
0032738677
-
The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease
-
Mirza, B., Hadberg, H., Thomsen, P., and Moos, T. (2000) The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease. Neuroscience, 95, 425-32.
-
(2000)
Neuroscience
, vol.95
, pp. 425-432
-
-
Mirza, B.1
Hadberg, H.2
Thomsen, P.3
Moos, T.4
-
142
-
-
0034895295
-
Parkin and Parkinson's disease
-
Mizuno, Y., Hattori, N., Mori, H., Suzuki, T., and Tanaka, K. (2001) Parkin and Parkinson's disease. Curr. Opin. Neurol., 14, 477-82.
-
(2001)
Curr. Opin. Neurol.
, vol.14
, pp. 477-482
-
-
Mizuno, Y.1
Hattori, N.2
Mori, H.3
Suzuki, T.4
Tanaka, K.5
-
143
-
-
0028171374
-
Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients
-
Mogi, M., Harada, M., Kondo, T., Riederer, P., Inagaki, H., Minami, M., and Nagatsu, T. (1994) Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients. Neurosci. Lett., 180, 147-50.
-
(1994)
Neurosci. Lett.
, vol.180
, pp. 147-150
-
-
Mogi, M.1
Harada, M.2
Kondo, T.3
Riederer, P.4
Inagaki, H.5
Minami, M.6
Nagatsu, T.7
-
144
-
-
0033597983
-
Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease
-
Mogi, M., Togari, A., Kondo, T., Mizuno, Y., Komure, O., Kuno, S., Ichinose, H., and Nagatsu, T. (1999) Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci. Lett., 270, 45-8.
-
(1999)
Neurosci. Lett.
, vol.270
, pp. 45-48
-
-
Mogi, M.1
Togari, A.2
Kondo, T.3
Mizuno, Y.4
Komure, O.5
Kuno, S.6
Ichinose, H.7
Nagatsu, T.8
-
145
-
-
0034640430
-
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity
-
Mohanakumar, K.P., Muralikrishnan, D., and Thomas, B. (2000) Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity. Brain Res., 864, 281-90.
-
(2000)
Brain Res.
, vol.864
, pp. 281-290
-
-
Mohanakumar, K.P.1
Muralikrishnan, D.2
Thomas, B.3
-
146
-
-
0029832301
-
Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury
-
Muhkin, A., Fan, L., and Faden, A.I. (1996) Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury. J. Neurosci., 16, 6012-6020.
-
(1996)
J. Neurosci.
, vol.16
, pp. 6012-6020
-
-
Muhkin, A.1
Fan, L.2
Faden, A.I.3
-
147
-
-
0035996544
-
Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease
-
Murray, T.K., Messenger, M.J., Ward, M.A., Woodhouse, S., Osborne, D.J., Duty, S., and O'Neill, M.J. (2002) Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease. Pharmacol. Biochem. Behav., 73, 455-66.
-
(2002)
Pharmacol. Biochem. Behav.
, vol.73
, pp. 455-466
-
-
Murray, T.K.1
Messenger, M.J.2
Ward, M.A.3
Woodhouse, S.4
Osborne, D.J.5
Duty, S.6
O'Neill, M.J.7
-
148
-
-
0033694060
-
Cytokines in Parkinson's disease
-
Nagatsu, T., Mogi, M., Ichinose, H., and Togari, A. (2000) Cytokines in Parkinson's disease. J. Neural. Transm. Suppl., 58, 143-51.
-
(2000)
J. Neural. Transm. Suppl.
, vol.58
, pp. 143-151
-
-
Nagatsu, T.1
Mogi, M.2
Ichinose, H.3
Togari, A.4
-
149
-
-
0036964810
-
Signaling pathways mediate the neuroprotective effects of GDNF
-
Neff, F., Noelker, C., Eggert, K., and Schlegel, J. (2002) Signaling pathways mediate the neuroprotective effects of GDNF. Ann. NY Acad. Sci., 973, 70-4.
-
(2002)
Ann. NY Acad. Sci.
, vol.973
, pp. 70-74
-
-
Neff, F.1
Noelker, C.2
Eggert, K.3
Schlegel, J.4
-
150
-
-
0032836680
-
Group-I metabotropic glutamate receptors: Hypotheses to explain their dual role in neurotoxicity and neuroprotection
-
Nicoletti, F., Bruno, V., Catania, M.V., Battaglia, G., Copani, A., Barbagallo, G., Ceña, V., Sanchez-Prieto, J., Spano, P.F., and Pizzi, M. (1999) Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection. Neuropharmacol, 38, 1477-1484.
-
(1999)
Neuropharmacol.
, vol.38
, pp. 1477-1484
-
-
Nicoletti, F.1
Bruno, V.2
Catania, M.V.3
Battaglia, G.4
Copani, A.5
Barbagallo, G.6
Ceña, V.7
Sanchez-Prieto, J.8
Spano, P.F.9
Pizzi, M.10
-
151
-
-
0030029427
-
Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders?
-
Nicoletti, F., Bruno, V., Copani, A., Casabona, G., and Knopfel, T. (1996) Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? Trends Neurosci., 19, 267-71.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 267-271
-
-
Nicoletti, F.1
Bruno, V.2
Copani, A.3
Casabona, G.4
Knopfel, T.5
-
152
-
-
0037435511
-
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
-
Nutt, J.G., Burchiel, K.J., Comella, C.L., Jankovic, J., Lang, A.E., Laws, E.R., Jr., Lozano, A.M., Penn, R.D., Simpson, R.K. Jr., Stacy, M., and Wooten, G.F. (2003) Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology, 60, 69-73.
-
(2003)
Neurology
, vol.60
, pp. 69-73
-
-
Nutt, J.G.1
Burchiel, K.J.2
Comella, C.L.3
Jankovic, J.4
Lang, A.E.5
Laws Jr., E.R.6
Lozano, A.M.7
Penn, R.D.8
Simpson Jr., R.K.9
Stacy, M.10
Wooten, G.F.11
-
153
-
-
0033695441
-
Levodopa motor complications in Parkinson's disease
-
Obeso, J.A., Olanow, C.W., and Nutt, J.G. (2000) Levodopa motor complications in Parkinson's disease. Trends Neurosci., 23, S2-7.
-
(2000)
Trends Neurosci.
, vol.23
-
-
Obeso, J.A.1
Olanow, C.W.2
Nutt, J.G.3
-
154
-
-
0014668762
-
Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate
-
Olney, J.W. (1969) Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science, 164, 719-721.
-
(1969)
Science
, vol.164
, pp. 719-721
-
-
Olney, J.W.1
-
155
-
-
0024843373
-
Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome)
-
Papp, M.I., Kahn, J.E., and Lantos, P.L. (1989) Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). J. Neurol. Sci., 94, 79-100.
-
(1989)
J. Neurol. Sci.
, vol.94
, pp. 79-100
-
-
Papp, M.I.1
Kahn, J.E.2
Lantos, P.L.3
-
156
-
-
17344368267
-
Mitochondrial dysfunction in idiopathic Parkinson disease
-
Parker, W.D., Jr. and Swerdlow, R.H. (1998) Mitochondrial dysfunction in idiopathic Parkinson disease. Am. J. Hum. Genet., 62, 758-762.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 758-762
-
-
Parker Jr., W.D.1
Swerdlow, R.H.2
-
157
-
-
0024456653
-
Effect of deprenyl on the progression of disablity in early Parkinson's disease
-
Parkinson Study Group
-
Parkinson Study Group (1989) Effect of deprenyl on the progression of disablity in early Parkinson's disease. New Eng. J. Med., 321, 1364-71.
-
(1989)
New Eng. J. Med.
, vol.321
, pp. 1364-1371
-
-
-
158
-
-
0027530638
-
Effects of tocopherol and deprenyl on the progression of disability in Parkinson's disease
-
Parkinson Study Group
-
Parkinson Study Group (1993) Effects of tocopherol and deprenyl on the progression of disability in Parkinson's disease. New Eng. J. Med., 328, 176-183.
-
(1993)
New Eng. J. Med.
, vol.328
, pp. 176-183
-
-
-
159
-
-
0034684139
-
Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial
-
Parkinson Study Group
-
Parkinson Study Group (2000) Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. JAMA, 284, 1931-8.
-
(2000)
JAMA
, vol.284
, pp. 1931-1938
-
-
-
160
-
-
0036894795
-
A controlled trial of rasagiline in early Parkinson disease: The TEMPO Study
-
Parkinson Study Group
-
Parkinson Study Group (2002) A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study. Arch. Neurol., 59, 1937-43.
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1937-1943
-
-
-
161
-
-
0037012478
-
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression
-
Parkinson Study Group
-
Parkinson Study Group (2002) Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA, 287, 1653-61.
-
(2002)
JAMA
, vol.287
, pp. 1653-1661
-
-
-
162
-
-
0029968460
-
Trinucleotide repeats in neurogenetic disorders
-
Paulson, H.L. and Fischbeck, K.H. (1996) Trinucleotide repeats in neurogenetic disorders. Annu. Rev. Neurosci., 19, 79-107.
-
(1996)
Annu. Rev. Neurosci.
, vol.19
, pp. 79-107
-
-
Paulson, H.L.1
Fischbeck, K.H.2
-
163
-
-
0032885411
-
Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: Time course and mechanisms
-
Pelligrini-Giampietro, D.E., Peruginelli, F., Meli, E., Cozzi, A., Albani-Torregrossa, S., Pellicciari, R., and Moroni, F. (1999) Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time course and mechanisms. Neuropharmacol., 38, 1607-1620.
-
(1999)
Neuropharmacol.
, vol.38
, pp. 1607-1620
-
-
Pelligrini-Giampietro, D.E.1
Peruginelli, F.2
Meli, E.3
Cozzi, A.4
Albani-Torregrossa, S.5
Pellicciari, R.6
Moroni, F.7
-
164
-
-
0020308323
-
Parkinson's disease: A disorder due to nigral glutathione deficiency?
-
Perry, T.L., Godin, D.V., and Hansen, S. (1982) Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci. Lett., 33, 305-10.
-
(1982)
Neurosci. Lett.
, vol.33
, pp. 305-310
-
-
Perry, T.L.1
Godin, D.V.2
Hansen, S.3
-
165
-
-
0022553605
-
Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
-
Perry, T.L. and Yong, V.W. (1986) Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci. Lett., 67, 269-74.
-
(1986)
Neurosci. Lett.
, vol.67
, pp. 269-274
-
-
Perry, T.L.1
Yong, V.W.2
-
166
-
-
0025720505
-
Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate
-
Piani, D., Frei, K., Do, K.Q., Cuenod, M., and Fontana, A. (1991) Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate. Neurosci. Lett., 133, 159-62.
-
(1991)
Neurosci. Lett.
, vol.133
, pp. 159-162
-
-
Piani, D.1
Frei, K.2
Do, K.Q.3
Cuenod, M.4
Fontana, A.5
-
167
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M.H., Levedan, C., Leroy, E., Ide, S.E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E.S., Chandrasekharappa, S., Athanassiadou, A., Pappetropoulso, T., Johnson, W.G., Lazzarini, A.M., Duvoisin, R.C., Di Iorio, G., Golbe, L.I., and Nussbaum, R.L. (1997) Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science, 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Levedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Pappetropoulso, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
169
-
-
0036523713
-
Clinical-pathological study of levodopa complications
-
Rajput, A.H., Fenton, M.E., Birdi, S., Macaulay, R., George, D., Rozdilsky, B., Ang, L.C., Senthilselvan, A., and Hornykiewicz, O. (2002) Clinical-pathological study of levodopa complications. Mov. Disord., 17, 289-96.
-
(2002)
Mov. Disord.
, vol.17
, pp. 289-296
-
-
Rajput, A.H.1
Fenton, M.E.2
Birdi, S.3
Macaulay, R.4
George, D.5
Rozdilsky, B.6
Ang, L.C.7
Senthilselvan, A.8
Hornykiewicz, O.9
-
170
-
-
0042382779
-
Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms
-
Ramirez, A.D., Wong, S.K., and Menniti, F.S. (2003) Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms. Eur. J. Pharmacol., 475, 29-35.
-
(2003)
Eur. J. Pharmacol.
, vol.475
, pp. 29-35
-
-
Ramirez, A.D.1
Wong, S.K.2
Menniti, F.S.3
-
171
-
-
0034126269
-
Medical treatment of levodopa-induced dyskinesias
-
Rascol, O. (2000) Medical treatment of levodopa-induced dyskinesias. Ann. Neurol., 47, S179-88.
-
(2000)
Ann. Neurol.
, vol.47
-
-
Rascol, O.1
-
172
-
-
0034682308
-
A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa
-
Rascol, O., Brooks, D.J., Korczyn, A.D., De Deyn, P.P., Clarke, C.E., and Lang, A.E. (2000) A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. N. Engl. J. Med., 342, 1484-91.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1484-1491
-
-
Rascol, O.1
Brooks, D.J.2
Korczyn, A.D.3
De Deyn, P.P.4
Clarke, C.E.5
Lang, A.E.6
-
173
-
-
0037461309
-
Neuroprotective agents for clinical trials in Parkinson's disease: A systematic assessment
-
Ravina, B.M., Fagan, S.C., Hart, R.G., Hovinga, C.A., Murphy, D.D., Dawson, T.M., and Marler, J.R. (2003) Neuroprotective agents for clinical trials in Parkinson's disease: A systematic assessment. Neurology, 60, 1234-40.
-
(2003)
Neurology
, vol.60
, pp. 1234-1240
-
-
Ravina, B.M.1
Fagan, S.C.2
Hart, R.G.3
Hovinga, C.A.4
Murphy, D.D.5
Dawson, T.M.6
Marler, J.R.7
-
174
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
Richter, C., Park, J.W., and Ames, B.N. (1988) Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA, 85, 6465-7.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
175
-
-
0026625534
-
Distribution of iron in different brain regions and subcellular compartments in Parkinson's disease
-
Riederer, P., Dirr, A,, Goetz, M., Sofic, E., Jellinger, K.,
-
(1992)
Ann. Neurol.
, vol.32
-
-
Riederer, P.1
Dirr, A.2
Goetz, M.3
Sofic, E.4
Jellinger, K.5
Youdim, M.B.6
-
176
-
-
0024557734
-
Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains
-
Riederer, P., Sofic, E., Rausch, W.D., Schmidt, B., Reynolds, G.P., Jellinger, K., and Youdim, M.B. (1989) Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains. J . Neurochem., 52, 515-20.
-
(1989)
J . Neurochem.
, vol.52
, pp. 515-520
-
-
Riederer, P.1
Sofic, E.2
Rausch, W.D.3
Schmidt, B.4
Reynolds, G.P.5
Jellinger, K.6
Youdim, M.B.7
-
177
-
-
0034088395
-
Parkinson's disease mortality and pesticide exposure in California 1984-1994
-
Ritz, B. and Yu, F. (2000) Parkinson's disease mortality and pesticide exposure in California 1984-1994. Int. J. Epidemiol., 29, 323-9.
-
(2000)
Int. J. Epidemiol.
, vol.29
, pp. 323-329
-
-
Ritz, B.1
Yu, F.2
-
178
-
-
0034609561
-
Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein
-
Rochet, J.C., Conway, K.A., and Lansbury, P.T., Jr. (2000) Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein. Biochemistry, 39, 10619-26.
-
(2000)
Biochemistry
, vol.39
, pp. 10619-10626
-
-
Rochet, J.C.1
Conway, K.A.2
Lansbury Jr., P.T.3
-
179
-
-
0031696407
-
Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: A target for neuroprotection
-
Rodriguez, M.C., Obeso, J.A., and Olanow, C.W. (1998) Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: a target for neuroprotection. Ann. Neurol., 44, S175-88.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Rodriguez, M.C.1
Obeso, J.A.2
Olanow, C.W.3
-
180
-
-
0034738134
-
Association of coffee and caffeine intake with the risk of Parkinson disease
-
Ross, G.W., Abbott, R.D., Petrovitch, H., Morens, D.M., Grandinetti, A., Tung, K.H., Tanner, C.M., Masaki, K.H., Blanchette, P.L., Curb, J.D., Popper, J.S., and White, L.R. (2000) Association of coffee and caffeine intake with the risk of Parkinson disease. JAMA, 283, 2674-9.
-
(2000)
JAMA
, vol.283
, pp. 2674-2679
-
-
Ross, G.W.1
Abbott, R.D.2
Petrovitch, H.3
Morens, D.M.4
Grandinetti, A.5
Tung, K.H.6
Tanner, C.M.7
Masaki, K.H.8
Blanchette, P.L.9
Curb, J.D.10
Popper, J.S.11
White, L.R.12
-
181
-
-
0000232034
-
A marker of oxyradical-mediated DNA damage (8-hydroxy-2′-deoxyguanosine) is increased in nigro-striatum of Parkinson's disease
-
Sanchez-Ramos, R.R., Overvik, E., and Ames, B.N. (1994) A marker of oxyradical-mediated DNA damage (8-hydroxy-2′ -deoxyguanosine) is increased in nigro-striatum of Parkinson's disease. Neurodegeneration, 3, 197-204.
-
(1994)
Neurodegeneration
, vol.3
, pp. 197-204
-
-
Sanchez-Ramos, R.R.1
Overvik, E.2
Ames, B.N.3
-
182
-
-
0033029823
-
CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo
-
Saporito, M.S., Brown, E.M., Miller, M.S., and Carswell, S. (1999) CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo. J. Pharmacol Exp. Ther., 288, 421-7.
-
(1999)
J. Pharmacol Exp. Ther.
, vol.288
, pp. 421-427
-
-
Saporito, M.S.1
Brown, E.M.2
Miller, M.S.3
Carswell, S.4
-
183
-
-
0030771894
-
Huntingtin localization in brains of normal and Huntington's disease patients
-
Sapp, E., Schwarz, C., Chase, K., Bhide, P.G., Young, A.B., Penney, J., Vonsattel, J.P., Aronin, N., and DiFiglia, M. (1997) Huntingtin localization in brains of normal and Huntington's disease patients. Ann. Neurol., 42, 604-12.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 604-612
-
-
Sapp, E.1
Schwarz, C.2
Chase, K.3
Bhide, P.G.4
Young, A.B.5
Penney, J.6
Vonsattel, J.P.7
Aronin, N.8
DiFiglia, M.9
-
184
-
-
0037176885
-
Neuroprotection and dopamine agonists
-
Schapira, A.H. (2002) Neuroprotection and dopamine agonists. Neurology, 58, S9-18.
-
(2002)
Neurology
, vol.58
-
-
Schapira, A.H.1
-
185
-
-
0031684326
-
Mitochondria in the etiology and pathogenesis of Parkinson's disease
-
Schapira, A.H., Gu, M., Taanman, J.W., Tabrizi, S.J., Seaton, T., Cleeter, M., and Cooper, J.M. (1998) Mitochondria in the etiology and pathogenesis of Parkinson's disease. Ann. Neurol., 44, S89-98.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Schapira, A.H.1
Gu, M.2
Taanman, J.W.3
Tabrizi, S.J.4
Seaton, T.5
Cleeter, M.6
Cooper, J.M.7
-
186
-
-
0026753557
-
Mitochondrial Function in Parkinson's disease
-
Schapira, A.H., Mann, V.M., Cooper, J.M., Krige, D., Jenner, P.J., and Marsden, C.D. (1992) Mitochondrial Function in Parkinson's disease. Ann. Neurol., 32, S116-24.
-
(1992)
Ann. Neurol.
, vol.32
-
-
Schapira, A.H.1
Mann, V.M.2
Cooper, J.M.3
Krige, D.4
Jenner, P.J.5
Marsden, C.D.6
-
187
-
-
0030950473
-
Dietary antioxidants and other dietary factors in the etiology of Parkinson's disease
-
Scheider, W.L., Hershey, L.A., Vena, J.E., Holmlund, T., Marshall, J.R., and Freudenheim (1997) Dietary antioxidants and other dietary factors in the etiology of Parkinson's disease. Mov. Disord., 12, 190-6.
-
(1997)
Mov. Disord.
, vol.12
, pp. 190-196
-
-
Scheider, W.L.1
Hershey, L.A.2
Vena, J.E.3
Holmlund, T.4
Marshall, J.R.5
Freudenheim, A.6
-
188
-
-
0027339887
-
2 receptors regulate the gene expresion of striatopallidal and striatonigral neurons
-
2 receptors regulate the gene expresion of striatopallidal and striatonigral neurons. J. Neurosci., 13, 1080-1087.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1080-1087
-
-
Schiffmann, S.N.1
Vanderhaeghen, J.-J.2
-
189
-
-
0034811597
-
Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system
-
Schoepp, D.D. (2001) Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J. Pharmacol. Exp. Ther., 299, 12-20.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 12-20
-
-
Schoepp, D.D.1
-
190
-
-
0032834028
-
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
-
Schoepp, D.D., Jane, D.E., and Monn, J.A. (1999) Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacol., 38, 1431-1476.
-
(1999)
Neuropharmacol.
, vol.38
, pp. 1431-1476
-
-
Schoepp, D.D.1
Jane, D.E.2
Monn, J.A.3
-
191
-
-
0031920247
-
Effects of macrophage migration inhibitory factor and macrophage migration stimulatory factor on function and survival of foetal dopaminergic grafts in the 6-hydroxydopamine rat model of Parkinson's disease
-
Schwarz, S.C., Schwarz, J., Sautter, J., and Oertel, W.H. (1998) Effects of macrophage migration inhibitory factor and macrophage migration stimulatory factor on function and survival of foetal dopaminergic grafts in the 6-hydroxydopamine rat model of Parkinson's disease. Exp. Brain Res., 120, 95-103.
-
(1998)
Exp. Brain Res.
, vol.120
, pp. 95-103
-
-
Schwarz, S.C.1
Schwarz, J.2
Sautter, J.3
Oertel, W.H.4
-
192
-
-
0037161283
-
Caffeinated clues and the promise of adenosine A(2A) antagonists in PD
-
Schwarzschild, M.A., Chen, J.F., and Ascherio, A. (2002) Caffeinated clues and the promise of adenosine A(2A) antagonists in PD. Neurology, 58, 1154-60.
-
(2002)
Neurology
, vol.58
, pp. 1154-1160
-
-
Schwarzschild, M.A.1
Chen, J.F.2
Ascherio, A.3
-
193
-
-
0032211830
-
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe, D.J. (1998) The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol., 8, 447-53.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
194
-
-
0037104723
-
An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
-
Sherer, T.B., Betarbet, R., Stout, A.K., Lund, S., Baptista, M., Panov, A.V., Cookson, M.R., and Greenamyre, J.T. (2002) An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J. Neurosci., 22, 7006-15.
-
(2002)
J. Neurosci.
, vol.22
, pp. 7006-7015
-
-
Sherer, T.B.1
Betarbet, R.2
Stout, A.K.3
Lund, S.4
Baptista, M.5
Panov, A.V.6
Cookson, M.R.7
Greenamyre, J.T.8
-
195
-
-
0037229425
-
Subcutanteous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation
-
Sherer, T.B., Kim, J.-H., Betarbet, R., and Greenamyre, J.T. (2003) Subcutanteous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. Exp. Neurol., 179, 9-16.
-
(2003)
Exp. Neurol.
, vol.179
, pp. 9-16
-
-
Sherer, T.B.1
Kim, J.-H.2
Betarbet, R.3
Greenamyre, J.T.4
-
196
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura, H., Hattori, N., Kubo, S., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K., and Suzuki, T. (2000) Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet., 25, 302-5.
-
(2000)
Nat. Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
197
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura, H., Schlossmacher, M.G., Hattori, N., Frosch, M.P., Trockenbacher, A., Schneider, R., Mizuno, Y., Kosik, K.S., and Selkoe, D.J. (2001) Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science, 293, 263-9.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
198
-
-
0032709404
-
Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease
-
Shimura-Miura, H., Hattori, N., Kang, D., Miyako, K., Nakabeppu, Y., and Mizuno, Y. (1999) Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease. Ann. Neurol., 46, 920-4.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 920-924
-
-
Shimura-Miura, H.1
Hattori, N.2
Kang, D.3
Miyako, K.4
Nakabeppu, Y.5
Mizuno, Y.6
-
199
-
-
0031711714
-
DATATOP: A decade of neuroprotective inquiry
-
Shoulson, I. (1998) DATATOP: a decade of neuroprotective inquiry. Ann. Neurol., 44, S160-6.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Shoulson, I.1
-
200
-
-
0031947245
-
Where do we stand on neuroprotection? Where do we go from here?
-
Shoulson, I. (1998) Where do we stand on neuroprotection? Where do we go from here? Mov. Disord., 13 Suppl. 1, 46-8.
-
(1998)
Mov. Disord.
, vol.13
, Issue.SUPPL. 1
, pp. 46-48
-
-
Shoulson, I.1
-
201
-
-
0030612117
-
Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
-
Shults, C.W., Haas, R.H., Passov, D., and Beal, M.F. (1997) Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann. Neurol., 42, 261-4.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 261-264
-
-
Shults, C.W.1
Haas, R.H.2
Passov, D.3
Beal, M.F.4
-
202
-
-
0036771852
-
Effects of coenzyme Q10 in early Parkinson disease: Evidence of slowing of the functional decline
-
Shults, C.W., Oakes, D., Kieburtz, K., Beal, M.F., Haas, R., Plumb, S., Juncos, J.L., Nutt, J., Shoulson, I., Carter, J., Kompoliti, K., Perlmutter, J.S., Reich, S., Stern, M., Watts, R.L., Kurlan, R., Molho, E., Harrison, M., and Lew, M. (2002) Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Arch. Neurol., 59, 1541-50.
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
Beal, M.F.4
Haas, R.5
Plumb, S.6
Juncos, J.L.7
Nutt, J.8
Shoulson, I.9
Carter, J.10
Kompoliti, K.11
Perlmutter, J.S.12
Reich, S.13
Stern, M.14
Watts, R.L.15
Kurlan, R.16
Molho, E.17
Harrison, M.18
Lew, M.19
-
203
-
-
0033813571
-
Neurotrophic factors in Alzheimer's and Parkinson's disease brain
-
Siegel, G.J. and Chauhan, N.B. (2000) Neurotrophic factors in Alzheimer's and Parkinson's disease brain. Brain Res. Brain Res. Rev., 33, 199-227.
-
(2000)
Brain Res. Brain Res. Rev.
, vol.33
, pp. 199-227
-
-
Siegel, G.J.1
Chauhan, N.B.2
-
204
-
-
0024348981
-
Glutamate neurotoxicity in culture depends on the presence of glutamane: Implications for the role of glial cells in normal and pathological brain development
-
Simantov, R. (1989) Glutamate neurotoxicity in culture depends on the presence of glutamane: implications for the role of glial cells in normal and pathological brain development. J. Neurochem., 52, 1694-9.
-
(1989)
J. Neurochem.
, vol.52
, pp. 1694-1699
-
-
Simantov, R.1
-
205
-
-
0032980279
-
Mitochondrial disorders: Clinical and genetic features
-
Simon, D.K. and Johns, D.R. (1999) Mitochondrial disorders: clinical and genetic features. Annu. Rev. Med., 50, 111-27.
-
(1999)
Annu. Rev. Med.
, vol.50
, pp. 111-127
-
-
Simon, D.K.1
Johns, D.R.2
-
206
-
-
0036259061
-
'Nature vs nurture' and incompletely penetrant mutations: Lessons from twin studies of Parkinson's disease
-
Simon, D.K., Lin, M.T., and Pascual-Leone, A. (2002) 'Nature vs nurture' and incompletely penetrant mutations: lessons from twin studies of Parkinson's disease. J. Neurol. Neurosurg. Psych., 72, 686-9.
-
(2002)
J. Neurol. Neurosurg. Psych.
, vol.72
, pp. 686-689
-
-
Simon, D.K.1
Lin, M.T.2
Pascual-Leone, A.3
-
207
-
-
0033544323
-
Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation
-
Simon, D.K., Pulst, S.M., Sutton, J.P., Browne, S.E., Beal, M.F., and Johns, D.R. (1999) Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation. Neurology, 53, 1787-93.
-
(1999)
Neurology
, vol.53
, pp. 1787-1793
-
-
Simon, D.K.1
Pulst, S.M.2
Sutton, J.P.3
Browne, S.E.4
Beal, M.F.5
Johns, D.R.6
-
208
-
-
0242300619
-
Alpha-Synuclein locus triplication causes Parkinson disease
-
Singleton, A., Farrer, M., Johnson, J., Singleton, A., Hague, S., Kachergus, J., Hulihan, M., Peuralinna, T., Dutra, A., Nussbaum, R., Lincoln, S., Crawley, A., Hanson, M., Maraganore, D., Adler, C., Cookson, M., Muenter, M., Baptista, M., Miller, D., Blancato, J., Hardy, J., and Gwinn-Hardy, K. (2003) Alpha-Synuclein locus triplication causes Parkinson disease. Science, 302, 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
209
-
-
0026644192
-
Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease
-
Sofic, E., Lange, K.W., Jellinger, K., and Riederer, P. (1992) Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci. Lett., 142, 128-30.
-
(1992)
Neurosci. Lett.
, vol.142
, pp. 128-130
-
-
Sofic, E.1
Lange, K.W.2
Jellinger, K.3
Riederer, P.4
-
210
-
-
0032584686
-
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies
-
Spillantini, M.G., Crowther, R.A., Jakes, R., Cairns, N.J., Lantos, P.L., and Goedert, M. (1998) Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neurosci. Lett., 251, 205-8.
-
(1998)
Neurosci. Lett.
, vol.251
, pp. 205-208
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Cairns, N.J.4
Lantos, P.L.5
Goedert, M.6
-
211
-
-
0034531475
-
The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy
-
Spillantini, M.G. and Goedert, M. (2000) The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Ann. NY Acad. Sci., 920, 16-27.
-
(2000)
Ann. NY Acad. Sci.
, vol.920
, pp. 16-27
-
-
Spillantini, M.G.1
Goedert, M.2
-
212
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini, M.G., Schmidt, M.L., Lee, V.M., Trojanowski, J.Q., Jakes, R., and Goedert, M. (1997) Alpha-synuclein in Lewy bodies. Nature, 388, 839-40.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
213
-
-
0001931238
-
Treatment of Central nervous System Degenerative Disorders
-
Hardman, J.G. and Limbird, L.E., Editors, Tenth Edition, McGraw-Hill
-
Standaert, D.G. and Young, A.B. (2001) Treatment of Central nervous System Degenerative Disorders, In: Hardman, J.G. and Limbird, L.E., Editors, Goodman and Gilman's Pharmacological Basis of Therapeutics, Tenth Edition, McGraw-Hill, pp. 549-620.
-
(2001)
Goodman and Gilman's Pharmacological Basis of Therapeutics
, pp. 549-620
-
-
Standaert, D.G.1
Young, A.B.2
-
214
-
-
0037378740
-
Neuroprotection in Parkinson's disease: Clinical trials
-
discussion S97-9
-
Stocchi, F. and Olanow, C.W. (2003) Neuroprotection in Parkinson's disease: clinical trials. Ann. Neurol., 53 Suppl. 3, S87-97; discussion S97-9.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Stocchi, F.1
Olanow, C.W.2
-
215
-
-
0026607343
-
The anti-parkinsonian drug amantadine inhibits the N-methyl-D-aspartic acid-evoked release of acetylcholine from rat neostriatum in a non-competitive way
-
Stoof, J.C., Booij, J., Drukarch, B., and Wolters, E.C. (1992) The anti-parkinsonian drug amantadine inhibits the N-methyl-D-aspartic acid-evoked release of acetylcholine from rat neostriatum in a non-competitive way. Eur. J. Pharm., 213, 439-43.
-
(1992)
Eur. J. Pharm.
, vol.213
, pp. 439-443
-
-
Stoof, J.C.1
Booij, J.2
Drukarch, B.3
Wolters, E.C.4
-
216
-
-
0032556050
-
Cellular distribution of adenosine A2A receptor mRNA in the primate striatum
-
Svenningsson, P., Le Maine, C., Aubert, I., Burbaud, P., Fredholm, B.B., and Bloch, B. (1998) Cellular distribution of adenosine A2A receptor mRNA in the primate striatum. J. Comp. Neurol., 399, 229-40.
-
(1998)
J. Comp. Neurol.
, vol.399
, pp. 229-240
-
-
Svenningsson, P.1
Le Maine, C.2
Aubert, I.3
Burbaud, P.4
Fredholm, B.B.5
Bloch, B.6
-
217
-
-
0031907128
-
Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders
-
Takeda, A., Mallory, M., Sundsmo, M., Honer, W., Hansen, L., and Masliah, E. (1998) Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders. Am. J. Pathol., 152, 367-72.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 367-372
-
-
Takeda, A.1
Mallory, M.2
Sundsmo, M.3
Honer, W.4
Hansen, L.5
Masliah, E.6
-
218
-
-
0033230119
-
Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species
-
Tanaka, J., Toku, K., Zhang, B., Ishihara, K., Sakanaka, M., and Maeda, N. (1999) Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species. Glia, 28, 85-96.
-
(1999)
Glia
, vol.28
, pp. 85-96
-
-
Tanaka, J.1
Toku, K.2
Zhang, B.3
Ishihara, K.4
Sakanaka, M.5
Maeda, N.6
-
219
-
-
0026608742
-
Epidemiology of Parkinson's disease
-
Tanner, C.M. (1992) Epidemiology of Parkinson's disease. Neurol. Clin., 10, 317-29.
-
(1992)
Neurol. Clin.
, vol.10
, pp. 317-329
-
-
Tanner, C.M.1
-
220
-
-
0037176809
-
Smoking and Parkinson's disease in twins
-
Tanner, C.M., Goldman, S.M., Aston, D.A., Ottman, R., Ellenberg, J., Mayeux, R., and Langston, J.W. (2002) Smoking and Parkinson's disease in twins. Neurology, 58, 581-8.
-
(2002)
Neurology
, vol.58
, pp. 581-588
-
-
Tanner, C.M.1
Goldman, S.M.2
Aston, D.A.3
Ottman, R.4
Ellenberg, J.5
Mayeux, R.6
Langston, J.W.7
-
221
-
-
0033608187
-
Parkinson disease in twins: An etiologic study
-
Tanner, C.M., Ottman, R., Goldman, S.M., Ellenberg, J., Chan, P., Mayeux, R., and Langston, J.W. (1999) Parkinson disease in twins: an etiologic study. JAMA, 281, 341-6.
-
(1999)
JAMA
, vol.281
, pp. 341-346
-
-
Tanner, C.M.1
Ottman, R.2
Goldman, S.M.3
Ellenberg, J.4
Chan, P.5
Mayeux, R.6
Langston, J.W.7
-
222
-
-
0033756901
-
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
-
Tatton, N.A. (2000) Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp. Neurol., 166, 29-43.
-
(2000)
Exp. Neurol.
, vol.166
, pp. 29-43
-
-
Tatton, N.A.1
-
223
-
-
0037444442
-
Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity
-
Taylor, D.L., Diemel, L.T., and Pocock, J.M. (2003) Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity. J. Neurosci., 23, 2150-60.
-
(2003)
J. Neurosci.
, vol.23
, pp. 2150-2160
-
-
Taylor, D.L.1
Diemel, L.T.2
Pocock, J.M.3
-
224
-
-
0035134830
-
Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease
-
Teismann, P. and Ferger, B. (2001) Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease. Synapse, 39, 167-74.
-
(2001)
Synapse
, vol.39
, pp. 167-174
-
-
Teismann, P.1
Ferger, B.2
-
225
-
-
0038389514
-
COX-2 and neurodegeneration in Parkinson's disease
-
Teismann, P., Vila, M., Choi, D.K., Tieu, K., Wu, D.C., Jackson-Lewis, V., and Przedborski, S. (2003) COX-2 and neurodegeneration in Parkinson's disease. Ann. N.Y. Acad. Sci., 991, 272-7.
-
(2003)
Ann. N.Y. Acad. Sci.
, vol.991
, pp. 272-277
-
-
Teismann, P.1
Vila, M.2
Choi, D.K.3
Tieu, K.4
Wu, D.C.5
Jackson-Lewis, V.6
Przedborski, S.7
-
226
-
-
0035871840
-
Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
-
Tikka, T., Fiebich, B.L., Goldsteins. G., Keinanen, R., and Koistinaho, J. (2001) Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J. Neurosci., 21, 2580-8.
-
(2001)
J. Neurosci.
, vol.21
, pp. 2580-2588
-
-
Tikka, T.1
Fiebich, B.L.2
Goldsteins, G.3
Keinanen, R.4
Koistinaho, J.5
-
227
-
-
0038054032
-
Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: Modulation by inhibitors of PI3 kinase and MEK
-
Ugarte, S.D., Lin, E., Klann, E., Zigmond, M.J., and Perez, R.G. (2003) Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: modulation by inhibitors of PI3 kinase and MEK. J. Neurosci. Res., 73, 105-12.
-
(2003)
J. Neurosci. Res.
, vol.73
, pp. 105-112
-
-
Ugarte, S.D.1
Lin, E.2
Klann, E.3
Zigmond, M.J.4
Perez, R.G.5
-
228
-
-
0029884473
-
Amantadine treatment is an independent predictor of improved survival in Parkinson's disease
-
Uitti, R., Rajput, A., Ahlskog, J., Offord, K., Schroeder, D., Ho, M., Prasad, M., Rajput, A., and Basran, P. (1996) Amantadine treatment is an independent predictor of improved survival in Parkinson's disease. Neurology, 46, 1551-1556.
-
(1996)
Neurology
, vol.46
, pp. 1551-1556
-
-
Uitti, R.1
Rajput, A.2
Ahlskog, J.3
Offord, K.4
Schroeder, D.5
Ho, M.6
Prasad, M.7
Rajput, A.8
Basran, P.9
-
229
-
-
0031566042
-
NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease
-
Wakabayashi, K., Matsumoto, K., Takayama, K., Yoshimoto, M., and Takahashi, H. (1997) NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease. Neurosci. Lett., 239, 45-8.
-
(1997)
Neurosci. Lett.
, vol.239
, pp. 45-48
-
-
Wakabayashi, K.1
Matsumoto, K.2
Takayama, K.3
Yoshimoto, M.4
Takahashi, H.5
-
230
-
-
0032546895
-
Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy
-
Wakabayashi, K., Yoshimoto, M., Tsuji, S., and Takahashi, H. (1998) Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy. Neurosci. Lett., 249, 180-2.
-
(1998)
Neurosci. Lett.
, vol.249
, pp. 180-182
-
-
Wakabayashi, K.1
Yoshimoto, M.2
Tsuji, S.3
Takahashi, H.4
-
231
-
-
0038084268
-
Prospective study of phobic anxiety and risk of Parkinson's disease
-
Weisskopf, M.G., Chen, H., Schwarzschild, M.A., Kawachi, I., and Ascherio, A. (2003) Prospective study of phobic anxiety and risk of Parkinson's disease. Mov. Disord., 18, 646-51.
-
(2003)
Mov. Disord.
, vol.18
, pp. 646-651
-
-
Weisskopf, M.G.1
Chen, H.2
Schwarzschild, M.A.3
Kawachi, I.4
Ascherio, A.5
-
232
-
-
0037785449
-
Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study
-
Whone, A.L., Watts, R.L., Stoessl, A.J., Davis, M., Reske, S., Nahmias, C., Lang, A.E., Rascol, O., Ribeiro, M.J., Remy, P., Poewe, W.H., Hauser, R.A., and Brooks, D.J. (2003) Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study. Ann. Neurol., 54, 93-101.
-
(2003)
Ann. Neurol.
, vol.54
, pp. 93-101
-
-
Whone, A.L.1
Watts, R.L.2
Stoessl, A.J.3
Davis, M.4
Reske, S.5
Nahmias, C.6
Lang, A.E.7
Rascol, O.8
Ribeiro, M.J.9
Remy, P.10
Poewe, W.H.11
Hauser, R.A.12
Brooks, D.J.13
-
233
-
-
0034123691
-
Mechanisms of neurodegenerative disorders: Part 1: Protein aggregates
-
Wolozin, B. and Behl, C. (2000) Mechanisms of neurodegenerative disorders: Part 1: protein aggregates. Arch. Neurol., 57, 793-6.
-
(2000)
Arch. Neurol.
, vol.57
, pp. 793-796
-
-
Wolozin, B.1
Behl, C.2
-
234
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
Wu, D.C., Jackson-Lewis, V., Vila, M., Tieu, K., Teismann, P., Vadseth, C., Choi, D.K., Ischiropoulos, H., and Przedborski, S. (2002) Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J. Neurosci., 22, 1763-71.
-
(2002)
J. Neurosci.
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
Choi, D.K.7
Ischiropoulos, H.8
Przedborski, S.9
-
235
-
-
0342331476
-
Cell death and apoptosis regulating proteins in Parkinson's disease - A cautionary note
-
Wullner, U., Kornhuber, J., Weller, M., Schulz, J.B., Loschmann, P.A., Riederer, P., and Klockgether, T. (1999) Cell death and apoptosis regulating proteins in Parkinson's disease-a cautionary note. Acta Neuropathol. (Berl.), 97, 408-12.
-
(1999)
Acta Neuropathol. (Berl.)
, vol.97
, pp. 408-412
-
-
Wullner, U.1
Kornhuber, J.2
Weller, M.3
Schulz, J.B.4
Loschmann, P.A.5
Riederer, P.6
Klockgether, T.7
-
236
-
-
0035964358
-
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease
-
Xia, X.G., Harding, T., Weller, M., Bieneman, A., Uney, J.B., and Schulz, J.B. (2001) Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease. Proc. Natl. Acad. Sci. USA, 98, 10433-8.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10433-10448
-
-
Xia, X.G.1
Harding, T.2
Weller, M.3
Bieneman, A.4
Uney, J.B.5
Schulz, J.B.6
-
237
-
-
0141593395
-
Minocycline enhances MPTP toxicity to dopaminergic neurons
-
Yang, L., Sugama, S., Chirichigno, J.W., Gregorio, J., Lorenzl, S., Shin, D.H., Browne, S.E., Shimizu, Y., Joh, T.H., Beal, M.F., and Albers, D.S. (2003) Minocycline enhances MPTP toxicity to dopaminergic neurons. J. Neurosci. Res., 74, 278-85.
-
(2003)
J. Neurosci. Res.
, vol.74
, pp. 278-285
-
-
Yang, L.1
Sugama, S.2
Chirichigno, J.W.3
Gregorio, J.4
Lorenzl, S.5
Shin, D.H.6
Browne, S.E.7
Shimizu, Y.8
Joh, T.H.9
Beal, M.F.10
Albers, D.S.11
-
238
-
-
0022619469
-
Monoamine oxidase B, smoking, and Parkinson's disease
-
Yong, V.W. and Perry, T.L. (1986) Monoamine oxidase B, smoking, and Parkinson's disease. J. Neurol. Sci., 72, 265-72.
-
(1986)
J. Neurol. Sci.
, vol.72
, pp. 265-272
-
-
Yong, V.W.1
Perry, T.L.2
-
239
-
-
0035568344
-
Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]
-
Youdim, M.B. and Weinstock, M. (2001) Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]. Cell Mol. Neurobiol., 21, 555-73.
-
(2001)
Cell Mol. Neurobiol.
, vol.21
, pp. 555-573
-
-
Youdim, M.B.1
Weinstock, M.2
-
240
-
-
0033539522
-
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
-
Yrjanheikki, J., Tikka, T., Keinanen, R., Goldsteins, G., Chan, P.H., and Koistinaho, J. (1999) A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc. Natl. Acad. Sci. USA, 96, 13496-500.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13496-13500
-
-
Yrjanheikki, J.1
Tikka, T.2
Keinanen, R.3
Goldsteins, G.4
Chan, P.H.5
Koistinaho, J.6
-
241
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang, Y., Gao, J., Chung, K.K., Huang, H., Dawson, V.L., and Dawson, T.M. (2000) Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc. Natl. Acad. Sci. USA, 97, 13354-9.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.K.3
Huang, H.4
Dawson, V.L.5
Dawson, T.M.6
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