Antibiotic prophylaxis in acute necrotizing pancreatitis: Yes or No?

Journal of the Pancreas

Volumn 5, Issue 3, 2004, Pages 161-164

  Pezzilli, Raffaele ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Acute necrotizing; Antibiotic prophylaxis; Clinical trials; Controlled clinical trial; Meta analysis; Pancreatitis

Indexed keywords

C REACTIVE PROTEIN; CEFUROXIME; CIPROFLOXACIN; IMIPENEM; METRONIDAZOLE; OFLOXACIN; PLACEBO; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ACUTE HEMORRHAGIC PANCREATITIS; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC THERAPY; BACTERIAL TRANSLOCATION; BACTERIUM CONTAMINATION; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DRUG CHOICE; ENTERIC FEEDING; FLUID THERAPY; HUMAN; INTENSIVE CARE; MINIMUM INHIBITORY CONCENTRATION; MORBIDITY; MORTALITY; MYCOSIS; NOTE; OUTCOMES RESEARCH; SAMPLE SIZE; SEPSIS;

ANTIBIOTIC PROPHYLAXIS; HUMANS; PANCREATITIS, ACUTE NECROTIZING;

EID: 3242661725     PISSN: 15908577     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (29)

1. Craig RM, Dordal E, Myles L. The use of ampicillin in acute pancreatitis. Ann Intern Med 1975; 83:831-2. [PMID 1106281]
2. Howes R, Zuidema GD, Cameron JL. Evaluation of prophylactic antibiotics in acute pancreatitis. J Surg Res 1975; 18:197-200. [PMID 1094193]
3. Finch WT, Sawyers JL, Schenker S. A prospective study to determine the efficacy of antibiotics in acute pancreatitis. Ann Surg 1976; 183:667-71. [PMID 788655]
4. Balthazar EJ, Ranson JH, Naidich DP, Megibow AJ, Caccavale R, Cooper MM. Acute pancreatitis: prognostic value of CT. Radiology 1985; 156:767-72. [PMID 4023241]
5. Bradley EL 3rd. A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. Arch Surg 1993; 128:586-90. [PMID 8489394]
6. Beger HG, Bittner R, Block S, Buchler M. Bacterial contamination of pancreatic necrosis. A prospective clinical study. Gastroenterology 1986; 91:433-8. [PMID 3522342]
7. Pederzoli P, Orcalli F, Falconi M, Bozzini L, Martini N. Penetration of mezlocillin into pancreatic juice. J Antimicrob Chemother 1986; 17:397. [PMID 3700296]
8. Pederzoli P, Falconi M, Bassi C, Vesentini S, Orcalli F, Scaglione F, et al. Ciprofloxacin penetration in pancreatic juice. Chemotherapy 1987; 33:397-401. [PMID 3428007]
9. Bassi C, Pederzoli P, Vesentini S, Falconi M, Bonora A, Abbas H, et al. Behavior of antibiotics during human necrotizing pancreatitis. Antimicrob Agents Chemother 1994; 38:830-6. [PMID 8031054]
10. Pederzoli P, Bassi C, Vesentini S, Campedelli A. A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem. Surg Gynecol Obstet 1993; 176:480-3. [PMID 8480272]
11. Luiten EJ, Hop WC, Lange JF, Bruining HA. Controlled clinical trial of selective decontamination for the treatment of severe acute pancreatitis. Ann Surg 1995; 222:57-65. [PMID 7618970]
12. Bassi C, Falconi M, Talamini G, Uomo G, Papaccio G, Dervenis C, et al. Controlled clinical trial of pefloxacin versus imipenem in severe acute pancreatitis. Gastroenterology 1998; 115:1513-7. [PMID 9834279]
13. Takeda K, Matsuno S, Ogawa M, Watanabe S, Atomi Y. Continuous regional arterial infusion (CRAI) therapy reduces the mortality rate of acute necrotizing pancreatitis: results of a cooperative survey in Japan. J Hepatobiliary Pancreat Surg 2001; 8:216-20. [PMID 11455482]
14. Maravi-Poma E, Gener J, Alvarez-Lerma F, Olaechea P, Blanco A, Dominguez-Munoz JE. Spanish Group for the Study of Septic Complications in Severe Acute Pancreatitis. Early antibiotic treatment (prophylaxis) of septic complications in severe acute necrotizing pancreatitis: a prospective, randomized, multicenter study comparing two regimens with imipenem-cilastatin. Intensive Care Med 2003; 29:1974-80. [PMID 14551680]
15. Sainio V, Kemppainen E, Puolakkainen P, Taavitsainen M, Kivisaari L, Valtonen V, et al. Early antibiotic treatment in acute necrotising pancreatitis. Lancet 1995; 346:663-7. [PMID 7658819]
16. Schwarz M, Isenmann R, Meyer H, Beger HG. Antibiotic use in necrotizing pancreatitis. Results of a controlled study. Dtsch Med Wochenschr 1997; 122:356-61. [PMID 9118789]
17. Nordback I, Sand J, Saaristo R, Paajanen H. Early treatment with antibiotics reduces the need for surgery in acute necrotizing pancreatitis. A single-center randomized study. J Gastrointest Surg 2001; 5:113-8. [PMID 11331472]
18. Manes G, Rabitti PG, Menchise A, Riccio E, Balzano A, Uomo G. Prophylaxis with meropenem of septic complications in acute pancreatitis: a randomized, controlled trial versus imipenem. Pancreas 2003; 27:e79-83. [PMID 14576501]
19. Delcenserie R, Yzet T, Ducroix JP. Prophylactic antibiotics in treatment of severe acute alcoholic pancreatitis. Pancreas 1996; 13:198-201. [PMID 8829189]
20. Sharma VK, Howden CW. Prophylactic antibiotic administration reduces sepsis and mortality in acute necrotizing pancreatitis: a meta-analysis. Pancreas 2001; 22:28-31. [PMID 11138967]
21. Gotzinger P, Wamser P, Barlan M, Sautner T, Jakesz R, Fugger R. Candida infection of local necrosis in severe acute pancreatitis is associated with increased mortality. Shock 2000; 14:320-3. [PMID 11028550]
22. De Waele JJ, Vogelaers D, Blot S, Colardyn F. Fungal infections in patients with severe acute pancreatitis and the use of prophylactic therapy. Clin Infect Dis 2003; 37:208-13. [PMID 12856213]
23. Isenmann R, Runzi M, Kron M, Kahl S, Kraus D, Jung N, et al. German Antibiotics in Severe Acute Pancreatitis Study Group. Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: a placebo-controlled, double-blind trial. Gastroenterology 2004; 126:997-1004. [PMID 15057739]
24. Kalfarentzos F, Kehagias J, Mead N, Kokkinis K, Gogos C. Enteral nutrition is superior to parenteral nutrition in severe acute pancreatitis: results of a randomised prospective trial. Br J Surg 1997; 84:1665-9. [PMID 9448611]
25. McClave SA, Greene LM, Snider HL, Makk LJ, Cheadle WG, Owens NA, et al. Comparison of the safety of early enteral vs. parenteral nutrition in mild acute pancreatitis. JPEN J Parenter Enteral Nutr 1997; 21:14-20. [PMID 9002079]
26. Windsor AC, Kanwar S, Li AG, Barnes E, Guthrie JA, Spark JI, et al. Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis. Gut 1998; 42:431-5. [PMID 9577354]
27. Pupelis G, Austrums E, Jansone A, Sprucs R, Wehbi H. Randomised trial of safety and efficacy of postoperative enteral feeding in patients with severe pancreatitis: preliminary report. Eur J Surg 2000; 166:383-7. [PMID 10881949]
28. Hamvas J, Schwab R, Pap A. Jejunal feeding in chronic pancreatitis with severe necrosis. JOP. J Pancreas (Online) 2001; 2:112-6. [PMID 11870333]
29. Dervenis C. Enteral nutrition in severe acute pancreatitis: future development. JOP. J Pancreas (Online) 2004; 5:60-3. [PMID 15007186]