Blood flow switching among pulmonary capillaries is decreased during high hematocrit

Journal of Applied Physiology

Volumn 97, Issue 2, 2004, Pages 522-526

  Baumgartner Jr , William A ^a   Peterson, Amanda J ^a   Presson Jr , Robert G ^a   Tanabe, Nobuhiro ^b   Jaryszak, Eric M ^a   Wagner Jr , Wiltz W ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Dogs; Isolated canine lung lobes; Pulmonary capillary recruitment; Pulmonary microcirculation

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CAPILLARY FLOW; CONTROLLED STUDY; ERYTHROCYTE; HEMATOCRIT; HEMODYNAMIC MONITORING; LUNG ALVEOLUS WALL; LUNG CAPILLARY; LUNG PERFUSION; MALE; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BLOOD PRESSURE; CAPILLARIES; DOGS; HEMATOCRIT; LUNG; MALE; PERFUSION; PULMONARY CIRCULATION;

EID: 3242661674     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00068.2003     Document Type: Article

References (34)

1. Bhattacharya J and Staub NC. Direct measurement of microvascular pressures in the isolated perfused dog lung. Science 210: 327-328, 1980.
2. Capen RL, Hanson WL, Latham LP, Dawson CA, and Wagner WW Jr. Distribution of pulmonary capillary transit times in recruited networks. J Appl Physiol 69: 473-478, 1990.
3. Capen RL, Latham LP, and Wagner WW Jr. Comparison of direct and indirect measurements of pulmonary capillary transit times. J Appl Physiol 62: 1150-1154, 1987.
4. Capen RL and Wagner WW Jr. Intrapulmonary blood flow redistribution during hypoxia increases gas exchange surface area. J Appl Physiol 52: 1575-1581, 1982.
5. Cokelet GR and Sarelius I. Perceived vessel lumen and cell-blood velocity ratio: impact on in vivo blood flow rate determination. Am J Physiol Heart Circ Physiol 262: H1156-H1163, 1992.
6. Dawson CA, Rickaby DA, and Linehan JH. Influence of size of emboli on extravascular lung water. J Appl Physiol 67: 663-670, 1989.
7. Fenton BM, Carr RT, and Cokelet GR. Nonuniform red cell distribution in 20 to 100 μm bifurcations. Microvasc Res 29: 103-126, 1985.
8. Gebb SA, Graham JA, Hanger CC, Godbey PS, Capen RL, Doerschuk CM, and Wagner WW Jr. Sites of leukocyte sequestration in the pulmonary microcirculation. J Appl Physiol 79: 493-497, 1995.
9. Godbey PS, Graham JA, Presson RG Jr, Wagner WW Jr, and Lloyd TC Jr. Effect of capillary pressure and lung distention on capillary recruitment. J Appl Physiol 79: 1142-1147, 1995.
10. Hanson WL, Emhardt JD, Bartek JP, Latham LP, Checkley LL, Capen RL, and Wagner WW Jr. Site of recruitment in the pulmonary microcirculation. J Appl Physiol 66: 2079-2083, 1989.
11. Hogg JC. Neutrophil kinetics and lung injury. Physiol Rev 67: 1249-1295, 1987.
12. Hogg JC, McLean T, Martin BA, and Wiggs B. Erythrocyte transit and neutrophil concentration in the dog lung. J Appl Physiol 65: 1217-1225, 1988.
13. Kiani MF, Cokelet GR, and Sarelius IR. Effect of diameter variability along a microvessel segment on pressure drop. Microvasc Res 45: 219-232, 1993.
14. Kiani MF, Pries AR, Hsu LL, Sarelius IH, and Cokelet GF. Fluctuations in microvascular blood flow parameters caused by hemodynamic mechanisms. Am J Physiol Heart Circ Physiol 266: H1822-H1828, 1994.
15. Lien DC, Wagner WW Jr, Capen RL, Haslett C, Hanson WL, Hofmeister SE, Hensen PM, and Worthen GS. Physiological neutrophil sequestration in the lung: visual evidence for localization in capillaries. J Appl Physiol 62: 1236-1243, 1987.
16. Lien DC, Worthen GS, Capen RL, Hanson WL, Checkley LL, Janke SJ, Hensen PM, and Wagner WW Jr. Neutrophil kinetics in the pulmonary microcirculation: effects of pressure and flow in the dependent lung. Am Rev Respir Dis 141: 953-959, 1990.
17. Okada O, Presson RG Jr, Godbey PS, Capen RL, and Wagner WW Jr. Temporal capillary perfusion patterns in single alveolar walls of intact dogs. J Appl Physiol 76: 380-386, 1994.
18. Okada O, Presson RG Jr, Kirk KR, Godbey PS, Capen RL, and Wagner WW Jr. Capillary perfusion patterns in single alveolar walls. J Appl Physiol 72: 1838-1844, 1992.
19. Osterloh K, Gaehtgens P, and Pries AR. Determination of microvascular flow pattern formation in vivo. Am J Physiol Heart Circ Physiol 278: H1142-H1152, 2000.
20. Perlo S, Jalowayski AA, Durand CM, and West JB. Distribution of red and white blood cells in alveolar walls. J Appl Physiol 38: 117-124, 1975.
21. Presson, RG Jr, Graham JA, Hanger CC, Godbey PS, Gebb SA, Sidner RA, Glenny RW, and Wagner WW Jr. Distribution of pulmonary capillary erythrocyte transit times. J Appl Physiol 79: 382-388, 1995.
22. Presson RG Jr, Hanger CC, Godbey PS, Graham JA, Lloyd TC Jr, and Wagner WW Jr. Effect of increasing flow on the distribution of pulmonary capillary transit times. J Appl Physiol 76: 1701-1711, 1994.
23. Presson RG Jr, Okada O, Godbey PS, Graham JA, Hanger CC, Glenny RW, and Wagner WW Jr. Stability of alveolar capillary opening pressures. J Appl Physiol 77: 1630-1637, 1994.
24. Pries AR, Neuhaus D, and Gaehtgens P. Blood viscosity in tube flow: dependence on diameter and hematocrit. Am J Physiol Heart Circ Physiol 263: H1770-H1778, 1992.
25. Pries AR, Secomb TW, and Gaehtgens P. Structure and hemodynamics of microvascular networks: heterogeneity and correlations. Am J Physiol Heart Circ Physiol 269: H1713-H1722, 1995.
26. Pries AR, Secomb TW, Gessner T, Gross JF, and Gaehtgens P. Resistance to blood flow in microvessels in vivo. Circ Res 75: 904-915, 1994.
27. Rong-Tsu Y and Fung YC. Model experiments on apparent blood viscosity and hematocrit in pulmonary alveoli. J Appl Physiol 35: 510-517, 1973.
28. Short AC, Montoya ML, Gebb SA, Presson RG Jr, Wagner WW Jr, and Capen RL. Pulmonary capillary diameters and recruitment characteristics in subpleural and interior networks. J Appl Physiol 80: 1568-1573, 1996.
29. Wagner WW Jr. Pulmonary microcirculatory observations in vivo under physiological conditions. J Appl Physiol 26: 375-377, 1969.
30. Wagner WW Jr, Brinkman PD, Barker DB, and Filley GF. Erythrocyte photomicrography: contrast control by monochromatic illumination. J Biol Photo Assn 37: 156-162, 1969.
31. Wagner WW Jr and Latham LP. Pulmonary capillary recruitment during airway hypoxia in the dog. J Appl Physiol 39: 900-905, 1975.
32. Wagner WW Jr, Latham LP, and Capen RL. Capillary recruitment during airway hypoxia: the role of pulmonary artery pressure. J Appl Physiol 47: 383-387, 1979.
33. Wagner WW Jr, Todoran TM, Tanabe N, Wagner TM, Tanner JA, Glenny RW, and Presson RG Jr. Pulmonary capillary perfusion: intraalveolar fractal patterns and interalveolar independence. J Appl Physiol 86: 825-831, 1999.
34. Wearn JT, Ernstene AC, Bromer AW, Barr JS, German WJ, and Zschiesche LJ. The normal behavior of the pulmonary blood vessels with observations on the intermittence of the flow of blood in the arterioles and capillaries. Am J Physiol 109: 236-256, 1934.