The role of osteogenic index, octahedral shear stress and dilatational stress in the ossification of a fracture callus

Medical Engineering and Physics

Volumn 26, Issue 6, 2004, Pages 493-501

  Gardner, Trevor Noel ^a,b   Mishra, Sanjay ^a   Marks, Laurence ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c Integrated Analysis Solutions   (United Kingdom)

Author keywords

Callus; Finite element model; Fracture healing; Osteogenic index

Indexed keywords

BONE; DATA ACQUISITION; DIFFERENTIATION (CALCULUS); FRACTURE; MEDICAL IMAGING; TISSUE;

BONE FRACTURE; HEALING; OSTEOGENIC INDEX;

SHEAR STRESS;

ADULT; ARTICLE; BIOMECHANICS; BONE DEVELOPMENT; BONE MATURATION; CALCULATION; CALLUS; CASE REPORT; DILATATIONAL STRESS; FRACTURE; FRACTURE HEALING; HUMAN; HYPOTHESIS; MALE; OCTAHEDRAL SHEAR STRESS; OSSIFICATION; PREDICTION; PRIORITY JOURNAL; SHEAR STRESS;

ADULT; BONY CALLUS; COMPUTER SIMULATION; DIAGNOSIS, COMPUTER-ASSISTED; DILATATION, PATHOLOGIC; FRACTURE HEALING; HUMANS; MALE; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; OSTEOGENESIS; OSTEOGENESIS, DISTRACTION; SHEAR STRENGTH; STRESS, MECHANICAL; TIBIAL FRACTURES; TREATMENT OUTCOME;

EID: 3242660119     PISSN: 13504533     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.medengphy.2004.03.009     Document Type: Article

References (29)

1. Cheal E.J., Mansman K.A., DiGioi III A.M., Hayes W.C., Perren S.M. Role of interfragmentary strain in fracture healing: ovine model of healing osteotomy. Journal of Orthopaedic Res. 9:1991;131-142
2. Goodship A.E., Kenwright J. The influence of induced micro movement upon the healing of experimental fractures. Journal of Bone and Joint Surgery. 67:1985;650-655
3. Kenwright J., Goodship A.E. Controlled mechanical stimulation in the treatment of tibial fractures. Clinical Orthopaedics and Related Research. 241:1989;36-47
4. Yamagishi M., Yoshimura Y. The biomechanics of fracture healing. Journal of Bone and Joint Surgery. 37A:1955;1035-1068
5. Carter D.R., Blenman P.R., Beaupre G.S. Correlations between mechanical stress history and tissue differentiation in initial fracture healing. Journal of Orthopaedic Research. 6:1988;736-748
6. Blenman P.R., Carter D.R., Beaupre G.S. Role of mechanical loading in progressive ossification of fracture callus. Journal of Orthopaedic Research. 7:1989;398-407
7. Claes L.E., Heigele C.A. Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing. Journal of Biomechanics. 32:1999;255-266
8. Ament C., Hofer E.P. A fuzzy logic model of fracture healing. Journal of Biomechanics. 33:2000;961-968
9. Prendergast P.J., Huiskes R. Finite element analysis of fibrous tissue morphogenesis - A study of the osteogenic index using a biphasic approach. Mechanics of Composite Materials. 32/2:1996;209-218
10. Gardner T.N., Marks L., Stoll T., Knothe-Tate M. The influence of mechanical stimulus on the pattern of tissue differentiation in a long bone fracture - An FEM study. Journal of Biomechanics. 33:2000;415-425
11. Sarmiento A., Latta L.L., Tarr R.R. Principles of fracture healing (Part 2). Murray J.A. Instructional course lectures. vol. 33:1984;83-106 CV Mosby Co, St. Louis
12. Sarmiento A., Latta L.L. Functional fracture bracing: tibia humerus ulna. 1995;Springer Verlag, Berlin. p. 239-240
13. Sevitt S. Bone repair and fracture healing in man. Cruess R., Mankin H., McKibbin B., Freeman M., Nachemson A. Current problems in orthopaedics. 1981;82-85 Churchil Livingstone
14. Carter D.R., Beaupre G.S., Giori N.J., Helms J.A. Mechanobiology of skeletal regeneration. Clinical Orthopaedics and Related Research. 355S:1998;41-45
15. Gardner T.N., Mishra S. The biomechanical environment of a bone fracture and its influence upon the morphology of healing. Journal of Medical Engineering and Physics. 25:2003;455-464
16. Gardner T.N., Stoll T., Marks L., Knothe-Tate M. Mathematical modelling of stress and strain in bone fracture repair tissue. Middleton J., Jones M.L., Pande G.N. Computer methods in biomechanics and biomedical engineering. Vol. 2:1998;247-254 Gordon and Breach Science Publisher, The Netherlands
17. Mishra S., Gardner T.N. Comparative two- and three-dimensional finite element modelling techniques for tibial fractures. Proceedings of the Institution of Mechanical Engineers, 215/H:2001;255-258
18. Denby P.P., Heaton B. Physics for radiologists. 1987;Blackwell Scientific Publications, Oxford, UK
19. Gardner T.N., Evans M., Kyberd P.J. An instrumented special linkage for monitoring relative three dimensional motion between fracture fragments. Journal of Biomechanical Engineering (Trans of ASME). 118:1996;586-594
20. Davey D.T., Connolly J.F. The biomechanical behaviourof healing canine radii and ribs. Journal of Biomechanics. 15:(4):1982;235-247
21. Perren S.M., Cordey J. Mechanical strain induction. Uhthoff H.K. Currents concepts of internal fixation of fractures. 1980;Springer Verlag, Berlin
22. Duck F.A. Physical properties of tissue. 1990;Academic Press, London, UK
23. Di Gioia A.M., Cheal E.J., Hayes W.C. Three dimensional strain fields in a uniform osteotomy gap. Journal of Biomechanical Engineering (Trans ASME). 108:1986;273-280
24. Huber-Betzer H., Brown T.D., Mattheck C. Some effects of global joint morphology on local stress aberations near imprecisely reduced intra-articular fractures. Journal of Biomechanics. 23:(8):1990;811-822
25. Lu T.W., O'Conner J.J., Taylor S.J.G., Walker P.S. Influence of muscle activity on forces in the femur: An in vivo study. Journal of Biomechanics. 30:1997;1101-1106
26. Nunamaker D.M. Experimental models of fracture repair. Clinical Orthopaedics and Related Research. 355S:1998;56-65
27. McKibbin B. The biology of fracture healing in long bones. Journal of Bone and Joint Surgery. 60B:1978;150-162
28. Einhorn T.A. The cell and molecular biology of fracture healing. Clinical Orthopaedics and Related Research. 355S:1998;7-21
29. Kenwright J., Gardner T.N. Mechanical influences on tibial fracture healing. Clinical Orthopaedics and Related Research. 355S:1998;179-190