Cardiac troponin T mutations in Chinese patients with hypertrophic cardiomyopathy

Chinese Medical Journal

Volumn 117, Issue 6, 2004, Pages 944-946

  Wu, Heng Fang ^a   Yang, Di ^a   Wan, Wen Hui ^a   Bian, Zhi Ping ^a   Xu, Jin Dan ^a   Ma, Wen Zhu ^a   Zhang, Ji Nan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Cardiac troponin T; Cardiomyopathy; Gene; Hypertrophic; Mutation

Indexed keywords

GENOMIC DNA; TROPONIN T;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHINESE; CONTROLLED STUDY; DISEASE COURSE; DNA EXTRACTION; DNA ISOLATION; DNA SEQUENCE; ELECTROCARDIOGRAPHY; EXON; FEMALE; GENE MUTATION; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; AGED; CARDIOMYOPATHY, HYPERTROPHIC; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; TROPONIN T;

EID: 3242659965     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Marian AJ, Roberts R. The Molecular Genetic Basis for Hypertrophic Cardiomyopathy. J Mol Cell Cardiol 2001;33: 655-670.
2. Garcia-Castro M, Reguero JR, Batalla A, et al. Hypertrophic cardiomyopathy: low frequency of mutations in the beta-myosin heavychain (MYH7) and cardiac troponin T (TNNT2) genes among Spanish patients. Clin Chem 2003; 49:1279-1285.
3. Van Driest SL, Ellsworth EG, Ommen SR, et al. Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy. Circulation 2003;108:445-451.
4. Mogensen J, Bahl A, Kubo T, et al. Comparison of fluorescent SSCP and denaturing HPLC analysis with direct sequencing for mutation screening in hypertrophic cardiomyopathy. J Med Genet 2003;40:e59.
5. Waldmuller S, Freund P, Mauch S, et al. Low-density DNA microarray are versatile tools to screen for known mutations in hypertrophic cardiomyopathy. Hum Mutat 2002;19;560-569.