Nucleophilic addition of ethyl 3-bromodifluoromethyl-3-benzyloxyacrylate to imines: An effective entry to novel gem-difluorinated amino esters and their derivatives

Synlett

Volumn , Issue 2, 2006, Pages 296-300

  Peng, Weimin ^a,b   Zhao, Jingwei ^a   He, Ping ^a   Zhu, Shizheng ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

Amino esters; Bromodifluoromethylated acrylate; Gem difluorinated; Imines; Nucleophilic addition

Indexed keywords

ACRYLIC ACID DERIVATIVE; ESTER DERIVATIVE; ETHYL 3 BROMODIFLUOROMETHYL 3 BENZYLOXYACRYLATE; ETHYLENE DERIVATIVE; GEM DIFLUORINATED GAMMA AMINO ESTER DERIVATIVE; IMINE; TETRAKIS(DIMETHYLAMINO)ETHYLENE; UNCLASSIFIED DRUG; ZINC;

ADDITION REACTION; ARTICLE; COLUMN CHROMATOGRAPHY; CYCLIZATION; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORINATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOPHILIC ADDITION REACTION; REACTION ANALYSIS; REACTION TIME; STEREOCHEMISTRY; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

EID: 32344449947     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-926225     Document Type: Article

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