Identification of a novel CoA synthase isoform, which is primarily expressed in the brain

Biochemical and Biophysical Research Communications

Volumn 341, Issue 4, 2006, Pages 995-1000

  Nemazanyy, Ivan ^a   Panasyuk, Ganna ^a   Breus, Oksana ^a   Zhyvoloup, Alexander ^a   Filonenko, Valeriy ^a   Gout, Ivan T ^a,b  

^a INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

CoASy ; CoASy ; Coenzyme A; Coenzyme A synthase; Protein isoform; Splice variant

Indexed keywords

ISOENZYME; LONG CHAIN FATTY ACID COENZYME A LIGASE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN TISSUE; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCREENING TEST; SIGNAL TRANSDUCTION; SPLICEOSOME;

EID: 32344444327     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.051     Document Type: Article

References (15)

1. R. Leonardi, Y.M. Zhang, C.O. Rock, and S. Jackowski Coenzyme A: back in action Prog. Lipid Res. 44 2-3 2005 125 153
2. A.G. Tahiliani, and C.J. Beinlich Pantothenic acid in health and disease Vitam. Horm. 46 1991 165 228
3. C.M. Smith, and C.R. Savage Jr. Regulation of coenzyme A biosynthesis by glucagon and glucocorticoid in adult rat liver parenchymal cells Biochem. J. 188 1 1980 175 184
4. D.K. Reibel, B.W. Wyse, D.A. Berkich, and J.R. Neely Regulation of coenzyme A synthesis in heart muscle: effects of diabetes and fasting Am. J. Physiol. 240 4 1981 H606 H611
5. R.A. McAllister, L.M. Fixter, and E.H. Campbell The effect of tumour growth on liver pantothenate, CoA, and fatty acid synthetase activity in the mouse Br. J. Cancer 57 1 1988 83 86
6. B. Zhou, S.K. Westaway, B. Levinson, M.A. Johnson, J. Gitschier, and S.J. Hayflick A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome Nat. Genet. 28 4 2001 345 349
7. A. Zhyvoloup, I. Nemazanyy, A. Babich, G. Panasyuk, N. Pobigailo, M. Vudmaska, V. Naidenov, O. Kukharenko, S. Palchevskii, L. Savinska, G. Ovcharenko, F. Verdier, T. Valovka, T. Fenton, H. Rebholz, M.L. Wang, P. Shepherd, G. Matsuka, V. Filonenko, and I.T. Gout Molecular cloning of CoA Synthase. The missing link in CoA biosynthesis J. Biol. Chem. 277 25 2002 22107 22110
8. M. Daugherty, B. Polanuyer, M. Farrell, M. Scholle, A. Lykidis, V. de Crecy-Lagard, and A. Osterman Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics J. Biol. Chem. 277 24 2002 21431 21439 Epub 2002 Mar 28
9. S. Aghajanian, and D.M. Worrall Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase) Biochem. J. 365 Pt. 1 2002 13 18
10. A. Zhyvoloup, I. Nemazanyy, G. Panasyuk, T. Valovka, T. Fenton, H. Rebholz, M.L. Wang, R. Foxon, V. Lyzogubov, V. Usenko, R. Kyyamova, O. Gorbenko, G. Matsuka, V. Filonenko, and I.T. Gout Subcellular localization and regulation of coenzyme A synthase J. Biol. Chem. 278 50 2003 50316 50321
11. I. Nemazanyy, G. Panasyuk, A. Zhyvoloup, G. Panayotou, I.T. Gout, and V. Filonenko Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism FEBS Lett. 578 3 2004 357 362
12. C.O. Rock, R.B. Calder, M.A. Karim, and S. Jackowski Pantothenate kinase regulation of the intracellular concentration of coenzyme A J. Biol. Chem. 275 2 2000 1377 1383
13. M. Yun, C.G. Park, J.Y. Kim, C.O. Rock, S. Jackowski, and H.W. Park Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A J. Biol. Chem. 275 36 2000 28093 28099
14. C. Lee, L. Atanelov, B. Modrek, and Y. Xing ASAP: the Alternative Splicing Annotation Project Nucleic Acids Res. 31 1 2003 101 105
15. N. Kim, D. Lim, S. Lee, and H. Kim ASePCR: alternative splicing electronic RT-PCR in multiple tissues and organs Nucleic Acids Res. 33 Web Server issue 2005 W681 W685