Hospital wastewater genotoxicity

Annals of Occupational Hygiene

Volumn 50, Issue 2, 2006, Pages 189-196

  Jolibois, B ^a,b   Guerbet, M ^a  

^a UNIVERSITÉ DE ROUEN   (France)

^b Centre Hospitalier Compiegne   (France)

Author keywords

Chemical water pollution; Genotoxicity; Hospital wastewater; Mutagenicity tests

Indexed keywords

CHEMICAL WATER POLLUTION; GENOTOXICITY; HOSPITAL WASTEWATER; MUTAGENICITY TESTS; ENVIRONMENTAL CONTROL; GENOTOXIC RESPONSE; GENOTOXICITIES; IMPACT ON THE ENVIRONMENT; MUTAGENICITY; RESPONSE INTENSITY;

HEALTH RISKS; HOSPITALS; MUTAGENESIS; TOXICITY; TUMORS; ENVIRONMENTAL MANAGEMENT; TESTING; WATER POLLUTION;

WASTEWATER; HOSPITALS;

RAIN;

ARTICLE; ASSAY; GENOTOXICITY; HOSPITAL WASTE; PRIORITY JOURNAL; RISK ASSESSMENT; SALMONELLA; SENSITIVITY ANALYSIS; SOS CHROMOTEST; TOXICITY TESTING; UNIVERSITY HOSPITAL; WASTE WATER; WATER POLLUTION; WATER SAMPLING;

DNA DAMAGE; FRANCE; HOSPITALS; HUMANS; MEDICAL WASTE; MUTAGENICITY TESTS; SALMONELLA TYPHIMURIUM; SOS RESPONSE (GENETICS); WASTE DISPOSAL, FLUID; WATER POLLUTION;

EID: 32244446051     PISSN: 00034878     EISSN: 14753162     Source Type: Journal    
DOI: 10.1093/annhyg/mei051     Document Type: Article

References (32)

1. Dayan J, Deguingand S, Truzman C et al. ( 1987) Application of the SOS chromotest to 10 pharmaceutical agents. Mutat Res; 187: 55-66.
2. de Lima Moraes DS, Jordao BQ. (2001) Evaluation of the genotoxic potential of municipal waste water discharged into the Paraguay River during periods of flood and drought. Environ Toxicol; 16: 113-6.
3. Doerger JU, Meier JR, Dobbs RA et al. (1992) Toxicity reduction evaluation at a municipal wastewater treatment plant using mutagenicity as an endpoint. Arch Environ Contam Toxicol; 22: 384-8.
4. Filipic M, Toman MJ (1996) Ecotoxicological studies using modified Ames bioassay. Water Sci Technol; 34: 1-7.
5. Gilbert RI. (1980) The analysis of fluctuation tests. Mutat Res; 74: 283-9.
6. Giuliani F, Koller T, Wurgler FE et al. (1996) Detection of genotoxic activity in native hospital waste water by the umuC test. Mutat Res; 368: 49-57.
7. Halling-Sorensen BH, Nors Nielsen S, Lanzky PF et al. (1998) Occurrence, fate and effects of pharmaceutical substances in the environment - a review. Chemosphere; 36: 357-93.
8. Hartmann A, Alder AC, Koller T et al. (1998) Identification of fluoroquinolones antibiotics as the main source of umuC genotoxicity in native hospital wastewater. Environ Toxicol Chem; 17: 377-82.
9. Hartmann A, Golet EM, Gartisier S et al. (1999) Primary DNA damage but not mutagenicity correlates with ciprofloxacin concentrations in german hospital wastewaters. Arch Environ Contam Toxicol; 36: 115-9.
10. Jolibois B, Guerbet M, Vassal S. (2002) Glutaraldehyde in hospital wastewater. Arch Environ Contam Toxicol; 42:137-44.
11. Jolibois B, Guerbet M, Vassal S. (2003) Detection of hospital wastewater genotoxicity with the SOS chromotest and Ames fluctuation test. Chemosphere; 51: 539-43.
12. Jolibois B, Guerbet M. (2005a) Evaluation of industrial, hospital and domestic wastewater genotoxicity with the Salmonella fluctuation test and the SOS chromotest. Mutat Res; 565: 151-62.
13. Jolibois B, Guerbet M. (2005b) Efficacy of two wastewater treatment plants in removing genotoxins. Arch Environ Contam Toxicol; 48: 289-95.
14. Kevekordes S, Mersch-Sundermann V, Burghaus CM et al. (1999) SOS induction of selected naturally occurring substances in Escherichia coli (SOS chromotest). Mutat Res; 445: 81-91.
15. Koivusalo M, Jaakkola JJ, Vartiainen T et al. (1994) Drinking water mutagenicity and gastrointestinal and urinary tract cancers: an ecological study in Finland. Am J Public Health; 84: 1223-8.
16. Koivusalo M, Vartiainen T, Hakulinen T et al. (1995) Drinking water mutagenicity and leukemia, lymphomas, and cancers of the liver, pancreas, and soft tissue. Arch Environ Health; 50: 269-76.
17. Koivusalo M, Pukkala E, Vartiainen T et al. (1997) Drinking water chlorination and cancer - a historical cohort study in Finland. Cancer Causes Control; 8: 192-200.
18. Kümmerer K. (2001) Drugs in the environment: emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources - a review. Chemosphere; 45: 957-69.
19. Legault R, Blaise C, Rokosh D et al. (1994) Comparative assessment of the SOS chromotest kit and the Mutatox test with the Salmonella plate incorporation (Ames test) and fluctuation tests for screening genotoxic agents. Environ Toxicol Water; 9: 45-57.
20. Levin DE, Hollstein M, Christman MF et al. (1982) A new Salmonella tester strain (TA 102) with AXT base pairs at the site of mutation detects oxidative mutagens. Proc Natl Acad Sci USA; 79: 7445-9.
21. Maron DM, Ames BN. (1983) Revised methods for the Salmonella mutagenicity test. Mutat Res; 113: 173-215.
22. Mersch-Sundermann V, Kevekordes S, Mochayedi S. (1991) Sources of variability of the Escherichia coli PQ37 genotoxicity assay (SOS chromotest). Mutat Res; 252: 51-60.
23. Mersch-Sundermann V, Mochayedi S, Kevekordes S. (1992) Genotoxicity of polycyclic aromatic hydrocarbons in Escherichia coli PQ37. Mutat Res; 278: 1-9.
24. Monarca S, Pasquini R, Arcaleni P. (1985) Detection of mutagens in unconcentrated and concentrated drinking water supplies before and after treatment using a microscale fluctuation test. Chemosphere; 14: 1069-80.
25. Quillardet P, Hofnung M. (1985) The SOS Chromotest, a colorimetric bacterial assay for genotoxins: procedures. Mutat Res; 147: 65-78.
26. Richardson ML, Bowron JM. (1985) The fate of pharmaceutical chemicals in the aquatic environment. J Pharm Pharmacol; 37: 1-12.
27. Rosenkranz HS, Mersch-Sundermann V, Klopman G. (1999) SOS chromotest and mutagenicity in Salmonella: evidence for mechanistic differences. Mutat Res; 431: 31-8.
28. Ruiz MJ, Marzin D. (1997) Genotoxicity of six pesticides by Salmonella mutagenicity test and SOS chromotest. Mutat Res; 390: 245-55.
29. Stahl RG. (1991) The genetic toxicology of organic compounds in natural waters and wastewaters. Ecotox Environ Saf; 22:94-125.
30. Steger-Hartmann T, Kümmerer K, Hartmann A. (1997) Biological degradation of cyclophosphamide and its occurrence in sewage water. Ecotoxicol Environ Saf; 36: 174-9.
31. Waters LC, Schenley RL, Owen BA et al. (1989) Biotesting of wastewater: a comparative study using the Salmonella and CHO assay systems. Environ Mol Mutagen; 14: 254-63.
32. White PA, Rasmussen JB, Blaise C. (1996) Sorption of organic genotoxins to particulate matter in industrial effluents. Environ Mol Mutagen; 27: 140-51.