In vitro and in vivo characterization of smooth small colony variants of Brucella abortus S19

Microbes and Infection

Volumn 8, Issue 2, 2006, Pages 363-371

  Jacob, J ^a   Hort, G M ^b   Overhoff, P ^a   Mielke, M E A ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Brucella abortus; Persistent infection; Small colony variants; Virulence

Indexed keywords

AGAR; CARRIER PROTEIN; GALAPTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM COLONY; BRUCELLA ABORTUS; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; GENE EXPRESSION; HYPEROSTOSIS; IN VITRO STUDY; IN VIVO STUDY; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SPLEEN;

ANIMALS; BACTERIAL PROTEINS; BRUCELLA ABORTUS; BRUCELLOSIS; CULTURE MEDIA; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LIVER; MICE; MICE, INBRED BALB C; SPLEEN; VIRULENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); BRUCELLA MELITENSIS BIOVAR ABORTUS;

EID: 32244443091     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micinf.2005.07.003     Document Type: Article

References (43)

1. C. Cheers, and F. Pagram Macrophage activation during experimental murine brucellosis: a basis for chronic infection Inf. Immun. 23 1979 197 205
2. G.M. Hort, J. Weisenburger, B. Borsdorf, C. Peters, M. Banai, H. Hahn, J. Jacob, and M.E. Mielke Delayed type hypersensitivity-associated disruption of splenic periarteriolar lymphatic sheaths coincides with temporary loss of IFN-gamma production and impaired eradication of bacteria in Brucella abortus-infected mice Microbes Infect. 5 2003 95 106
3. M.E.A. Mielke, I.B. Autenrieth, and T.K. Held The immune response in mice challenged with bacterial infections S.H.E. Kaufmann D. Kabelitz Meth. Microbiol. 32 2002 359 401
4. N.P. Moyer, L.A. Holcomb, and W.J. Hausler Brucella A.H. Balows W.J. Herrmann K.L. Isenberg H.D. Shadomy H.J. Manual of Clinical Microbiology 1991 Washington 457 461
5. R. Vemulapalli, J.R. McQuiston, G.G. Schurig, N. Sriranganathan, S.M. Halling, and S.M. Boyle Identification of an IS711 element interrupting the wboA gene of Brucella abortus vaccine strain RB51 and a PCR assay to distinguish strain RB51 from other Brucella species and strains Clin. Diagn. Lab. Immunol. 6 1999 760 764
6. A.J. Lesse, A.A. Campagnari, W.E. Bittner, and M.A. Apicella Increased resolution of lipopolysaccharides and lipooligosaccharides utilizing tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis J. Immunol. Methods 126 1990 109 117
7. A. Gravesen, P. Warthoe, S. Knochel, and K. Thirstrup Restriction fragment differential display of pediocin-resistant Listeria monocytogenes 412 mutants shows consistent overexpression of a putative beta-glucoside-specific PTS system Microbiol. 146 2000 1381 1389
8. C.L. Baldwin, and A.J. Winter Macrophages and Brucella Immunol. Ser. 60 1994 363 380
9. G. Richarme, A. el Yaagoubi, and M. Kohiyama The MglA component of the binding protein-dependent galactose transport system of Salmonella typhimurium is a galactose-stimulated ATPase J. Biol. Chem. 268 1993 9473 9477
10. S. Kohler, S. Michaux-Charachon, F. Porte, M. Ramuz, and J.P. Liautard What is the nature of the replicative niche of a stealthy bug named Brucella? Trends Microbiol. 11 2003 215 219
11. W. Braun, and B.A. Bonestell Independent variation of characteristics in Brucella abortus variants and their detection Am. J. Vet. Res. 8 1947 386 390
12. J. Ko, and G.A. Splitter Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans Clin. Microbiol. Rev. 16 2003 65 78
13. R.E. Price, J.W. Templeton, and L.G. Adams Survival of smooth, rough and transposon mutant strains of Brucella abortus in bovine mammary macrophages Vet. Immunol. Immunopathol. 26 1990 353 365
14. D. Monreal, M.J. Grillo, D. Gonzalez, C.M. Marin, M.J. De Miguel, I. Lopez-Goni, J.M. Blasco, A. Cloeckaert, and I. Moriyon Characterization of Brucella abortus O-polysaccharide and core lipopolysaccharide mutants and demonstration that a complete core is required for rough vaccines to be efficient against Brucella abortus and Brucella ovis in the mouse model Infect. Immun. 71 2003 3261 3271
15. G.G. Schurig, R.M. Roop 2nd, T. Bagchi, S. Boyle, D. Buhrman, and N. Sriranganathan Biological properties of RB51; a stable rough strain of Brucella abortus Vet. Microbiol. 28 1991 171 188
16. C.A. Allen, L.G. Adams, and T.A. Ficht Transposon-derived Brucella abortus rough mutants are attenuated and exhibit reduced intracellular survival Infect. Immun. 66 1998 1008 1016
17. M.G. Stevens, S.C. Olsen, G.W. Pugh Jr., and M.V. Palmer Immune and pathologic responses in mice infected with Brucella abortus 19, RB51, or 2308 Infect. Immun. 62 1994 3206 3212
18. M.P. Jimenez de Bagues, P.H. Elzer, S.M. Jones, J.M. Blasco, F.M. Enright, G.G. Schurig, and A.J. Winter Vaccination with Brucella abortus rough mutant RB51 protects BALB/c mice against virulent strains of Brucella abortus, Brucella melitensis, and Brucella ovis Infect. Immun. 62 1994 4990 4996
19. M.T. Alvarez-Martinez, J. Machold, C. Weise, H. Schmidt-Eisenlohr, C. Baron, and B. Rouot The Brucella suis homologue of the Agrobacterium tumefaciens chromosomal virulence operon chvE is essential for sugar utilization but not for survival in macrophages J. Bacteriol. 183 2001 5343 5351
20. P.C. Hong, R.M. Tsolis, and T.A. Ficht Identification of genes required for chronic persistence of Brucella abortus in mice Infect. Immun. 68 2000 4102 4107
21. P. Lestrate, R.M. Delrue, I. Danese, C. Didembourg, B. Taminiau, P. Mertens, X. De Bolle, A. Tibor, C.M. Tang, and J.J. Letesson Identification and characterization of in vivo attenuated mutants of Brucella melitensis Mol. Microbiol. 38 2000 543 551
22. P. Lestrate, A. Dricot, R.M. Delrue, C. Lambert, V. Martinelli, X. De Bolle, J.J. Letesson, and A. Tibor Attenuated signature-tagged mutagenesis mutants of Brucella melitensis identified during the acute phase of infection in mice Infect. Immun. 71 2003 7053 7060
23. F.M. Tatum, P.G. Detilleux, J.M. Sacks, and S.M. Halling Construction of Cu-Zn superoxide dismutase deletion mutants of Brucella abortus: analysis of survival in vitro in epithelial and phagocytic cells and in vivo in mice Infect. Immun. 60 1992 2863 2869
24. P.C. Canning Phagocyte function in resistance to brucellosis L.G. Adams Advances in Brucellosis Research 1990 Texas A&M University Press College Station 151 163
25. J.M. Kemner, X. Liang, and E.W. Nester The Agrobacterium tumefaciens virulence gene chvE is part of a putative ABC-type sugar transport operon J. Bacteriol. 179 1997 2452 2458
26. B. Rouot, M.T. Alvarez-Martinez, C. Marius, P. Menanteau, L. Guilloteau, R.A. Boigegrain, R. Zumbihl, D. O'Callaghan, N. Domke, and C. Baron Production of the type IV secretion system differs among Brucella species as revealed with VirB5- and VirB8-specific antisera Infect. Immun. 71 2003 1075 1082
27. D.O. Sanchez, R.O. Zandomeni, S. Cravero, R.E. Verdun, E. Pierrou, P. Faccio, G. Diaz, S. Lanzavecchia, F. Aguero, A.C. Frasch, S.G. Andersson, O.L. Rossetti, O. Grau, and R.A. Ugalde Gene discovery through genomic sequencing of Brucella abortus Infect. Immun. 69 2001 865 868
28. V.G. DelVecchio, V. Kapatral, P. Elzer, G. Patra, and C.V. Mujer The genome of Brucella melitensis Vet. Microbiol. 90 2002 587 592
29. R.M. Delrue, P. Lestrate, A. Tibor, J.J. Letesson, and X. De Bolle Brucella pathogenesis, genes identified from random large-scale screens FEMS Microbiol. Lett. 231 2004 1 12
30. N. Vizcaino, A. Cloeckaert, M.S. Zygmunt, and L. Fernandez-Lago Characterization of a Brucella species 25-kb DNA fragment deleted from Brucella abortus reveals a large gene cluster related to the synthesis of a polysaccharide Infect. Immun. 69 2001 6738 6748
31. G. Tsoktouridis, C.A. Merz, S.P. Manning, R. Giovagnoli-Kurtz, L.E. Williams, C.V. Mujer, S. Hagius, P. Elzer, R.J. Redkar, G. Patra, and V.G. DelVecchio Molecular characterization of Brucella abortus chromosome II recombination J. Bacteriol. 185 2003 6130 6136
32. M. Eschenbrenner, M.A. Wagner, T.A. Horn, J.A. Kraycer, C.V. Mujer, S. Hagius, P. Elzer, and V.G. DelVecchio Comparative proteome analysis of Brucella melitensis vaccine strain Rev 1 and a virulent strain, 16:M J. Bacteriol. 184 2002 4962 4970
33. S.H. Baek, G. Rajashekara, G.A. Splitter, and J.P. Shapleigh Denitrification genes regulate Brucella virulence in mice J. Bacteriol. 186 2004 6025 6031
34. G. Briones, N. Inon de Iannino, M. Steinberg, and R.A. Ugalde Periplasmic cyclic 1,2-beta-glucan in Brucella spp. is not osmoregulated Microbiol. 143 1997 1115 1124
35. N.I. de Iannino, G. Briones, F. Iannino, and R.A. Ugalde Osmotic regulation of cyclic 1,2-beta-glucan synthesis Microbiol. 146 2000 1735 1742
36. J. Celli, C. de Chastellier, D.M. Franchini, J. Pizarro-Cerda, E. Moreno, and J.P. Gorvel Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum J. Exp. Med. 198 2003 545 556
37. S. Kohler, V. Foulongne, S. Ouahrani-Bettache, G. Bourg, J. Teyssier, M. Ramuz, and J.P. Liautard The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell Proc. Natl. Acad. Sci. USA 99 2002 15711 15716
38. R.M. Roop 2nd, G.T. Robertson, G.P. Ferguson, L.E. Milford, M.E. Winkler, and G.C. Walker Seeking a niche: putative contributions of the hfq and bacA gene products to the successful adaptation of the brucellae to their intracellular home Vet. Microbiol. 90 2002 349 363
39. J. Pizarro-Cerda, S. Meresse, R.G. Parton, G. van der Goot, A. Sola-Landa, I. Lopez-Goni, E. Moreno, and J.P. Gorvel Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes Infect. Immun. 66 1998 5711 5724
40. L. Eskra, A. Canavessi, M. Carey, and G. Splitter Brucella abortus genes identified following constitutive growth and macrophage infection Infect. Immun. 69 2001 7736 7742
41. R.M. Crawford, L. Van De Verg, L. Yuan, T.L. Hadfield, R.L. Warren, E.S. Drazek, H.H. Houng, C. Hammack, K. Sasala, T. Polsinelli, J. Thompson, and D.L. Hoover Deletion of purE attenuates Brucella melitensis infection in mice Infect. Immun. 64 1996 2188 2192
42. M.L. Boschiroli, S. Ouahrani-Bettache, V. Foulongne, S. Michaux-Charachon, G. Bourg, A. Allardet-Servent, C. Cazevieille, J.P. Liautard, M. Ramuz, and D. O'Callaghan The Brucella suis virB operon is induced intracellularly in macrophages Proc. Natl. Acad. Sci. USA 99 2002 1544 1549
43. G.M. Rosinha, D.A. Freitas, A. Miyoshi, V. Azevedo, E. Campos, S.L. Cravero, O. Rossetti, G. Splitter, and S.C. Oliveira Identification and characterization of a Brucella abortus ATP-binding cassette transporter homolog to Rhizobium meliloti ExsA and its role in virulence and protection in mice Infect. Immun. 70 2002 5036 5044