Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatography

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 832, Issue 1, 2006, Pages 114-120

  Davies, Benjamin J ^a,b   Herbert, Megan K ^a   Culbert, Julie A ^b   Pyke, Simon M ^b   Coller, Janet K ^b   Somogyi, Andrew A ^b   Milne, Robert W ^c   Sallustio, Benedetta C ^a,b  

^a QUEEN ELIZABETH HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

Enantiomer separation; HPLC; Perhexiline

Indexed keywords

LIQUID CHROMATOGRAPHY; POLYMERS; SENSITIVITY ANALYSIS; TOXICITY;

NEUROLOGICAL TOXICITY; POLYMORPHIC CYTOCHROME;

PLASMAS;

ACETYLSALICYLIC ACID; ALENDRONIC ACID; ALLOPURINOL; AMILORIDE; AMIODARONE; AMISULPRIDE; AMITRIPTYLINE; AMLODIPINE; AMOXICILLIN; AMPHOTERICIN; ATENOLOL; ATORVASTATIN; ATROPINE; AZATHIOPRINE; BECLOMETASONE; BENZATROPINE; BIPERIDEN; CALCITRIOL; CARBAMAZEPINE; CARVEDILOL; CEFTAZIDIME; CELECOXIB; CLONAZEPAM; ENOXAPARIN; ERGOCALCIFEROL; ISOCYANIC ACID DERIVATIVE; METHANOL; PERHEXILINE MALEATE; PEXSIG; UNINDEXED DRUG; WATER;

ACCURACY; AGED; ARTICLE; CASE REPORT; COLUMN CHROMATOGRAPHY; CONSTANTS AND COEFFICIENTS; DERIVATIZATION; DIASTEREOISOMER; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISPOSITION; DRUG SCREENING; ENANTIOMER; ENANTIOSELECTIVITY; FEMALE; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; STEREOCHEMISTRY;

AGED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PERHEXILINE; REFERENCE STANDARDS; SPECTROMETRY, FLUORESCENCE; STEREOISOMERISM;

EID: 32244437395     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.12.046     Document Type: Article

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