BCL-XL expression levels influence differential regional astrocytic susceptibility to 1,3-dinitrobenzene

NeuroToxicology

Volumn 27, Issue 2, 2006, Pages 192-200

  Phelka, Amanda D ^a   Sadoff, Margaret M ^b   Martin, Bradley P ^a   Philbert, Martin A ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Toxics Unit   (United States)

Author keywords

Astrocytes; BCL XL; Dinitrobenzene

Indexed keywords

1,3 DINITROBENZENE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SUCCINATE DEHYDROGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; BRAIN STEM; DISEASE PREDISPOSITION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; IN VITRO STUDY; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TISSUE HOMOGENATE;

ANIMALS; ASTROCYTES; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BRAIN CHEMISTRY; BRAIN STEM; DINITROBENZENES; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE POTENTIALS; MICROSCOPY, CONFOCAL; MITOCHONDRIA; RATS; RATS, INBRED F344; RNA; SUCCINATE DEHYDROGENASE; TRANSFECTION;

ANIMALIA;

EID: 32244436870     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2005.09.006     Document Type: Article

References (21)

1. A.M. Brambrink, A. Schneider, H. Noga, A. Astheimer, B. Gotz, I. Korner, A. Heimann, M. Welschaf, and O. Kempski Tolerance inducing dose of 3-nitropropionic acid modulates BCL-2 and BAX balance in rat brain: a potential mechanism of chemical preconditioning J Cereb Blood Flow Metab 20 10 2000 1425 1436
2. D.S. Cassarino, and J.P. Bennett An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration Brain Res 29 1999 1 25
3. J.B. Cavanagh Selective vulnerability in acute energy deprivation syndromes Neuropathol Appl Neurobiol 19 1993 461 470
4. R.M. Chalmers-Redman, A.D. Fraser, W.Y. Ju, J. Wadia, N.A. Tatton, and W.G. Tatton Mechanisms of nerve cell death: apoptosis or necrosis after cerebral ischaemia Internat Rev Neurobiol 40 1997 1 25
5. 2+ trigger site Arch Biochem Biophys 195 2 1979 460 467
6. Y. Hu, M.A. Benedict, D. Wu, N. Inohara, and G. Nuñez BCL-XL interacts with Apaf-1 and inhibits Apaf-1 dependent caspase-9 activation Proc Natl Acad Sci USA 95 8 1998 4386 4391
7. 2+-induced membrane transition in mitochondria. 1. The protective mechanisms Arch Biochem Biophys 195 2 1979 453 459
8. S. Jayanthi, B.D. Lewis, and J.L. Cadet Fas-induced apoptosis of glioma cells is associated with down-regulation of the hSCO1 protein, a subunit of complex IV Brain Res Mol Brain Res 91 1-2 2001 131 136
9. P. Kugler, S. Vogel, and M. Gehm Quantitative succinate dehydrogenase histochemistry in the hippocampus of aged rats Histochem 88 1988 299 308
10. J.J. Lemasters, A.L. Nieminen, T. Qian, L.C. Trost, S. Elmore, Y. Nishimura, R.S. Crowe, W.E. Cascio, C.A. Bradham, D.A. Brenner, and B. Herman The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy Biochim Biophys Acta 1366 1998 177 195
11. J.J. Lemasters, A.L. Nieminen, T. Qian, L.C. Trost, and B. Herman The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury Mol Cell Biochem 174 1997 159 165
12. J.J. Lemasters, T. Qian, C.A. Bradham, D.A. Brenner, W.E. Cascio, L.C. Trost, Y. Nishimura, A.L. Nieminen, and B. Herman Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death J Bioenerg Biomemb 31 4 1999 305 319
13. I. Marzo, C. Brenner, N. Zamzami, S.A. Susin, G. Beutner, D. Brdiczka, R. Remy, Z. Xie, J.C. Reed, and G. Kroemer The permeability transition pore complex: a target for apoptosis regulation by caspases and BCL-2 related proteins J Exp Med 187 8 1998 1261 1271
14. S. Murphy Generation of astrocyte cultures from normal and neoplastic central nervous system MP. Conn Methods in Neurosciences: Cell Culture 1990 Academic Press San Diego 33 46
15. A.L. Nieminen, G.J. Gores, J.M. Bond, R. Imberti, B. Herman, and J.J. Lemasters A novel cytotoxicity screening assay using a multiwell fluorescence scanner Toxicol Appl Pharmacol 115 2 1992 147 155
16. A.D. Phelka, M.J. Beck, and M.A. Philbert 1,3-Dinitrobenzene inhibits mitochondrial complex II in rat and mouse brainstem and cortical astrocytes Neurotoxicol 24 2003 403 415
17. R. Raghupathi, K.I. Strauss, C. Zhang, S. Krajewski, J.C. Reed, and T.K. McIntosh Temporal alterations in cellular Bax:Bcl-2 Ratio following traumatic brain injury in the rat J Neurotrauma 20 5 2003 421 435
18. R.B. Tjalkens, A.D. Phelka, and M.A. Philbert Regional variation in the activation threshold for 1. 3-DNB-induced mitochondrial permeability transition (MPT) in brainstem and cortical astrocytes Neurotoxicol 24 2003 391 401
19. R.B. Tjalkens, M.M. Ewing, and M.A. Philbert Differential cellular regulation of the mitochondrial permeability transition in an in vitro model of 1,3-dinitrobenzene-induced encephalopathy Brain Res 874 2 2000 165 177
20. G.A. Veech, J. Dennis, P.M. Keeney, C.P. Fall, R.H. Swerdlow, W.D. Parker, and J.D. Bennett Disrupted mitochondrial electron transport function increases expression of anti-apoptotic Bcl-2 and Bcl-XL proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress J Neurosci Res 61 2000 693 700
21. G.J. Zhang, I. Kimijima, M. Onda, M. Kanno, H. Sato, T. Watanabe, A. Tsuchiya, R. Abe, and S. Takenoshita Tamoxifen-induced apoptosis in breast cancer cells relates to down regulation of bcl-2, but not bax and bcl-xl without alteration of p53 protein levels Clin Cancer Res 5 10 1999 2971 2977