A study of molecular mimicry and immunological cross-reactivity between hepatitis B surface antigen and myelin mimics

Clinical and Developmental Immunology

Volumn 12, Issue 3, 2005, Pages 217-224

  Bogdanos, Dimitrios Petrou ^a   Smith, Heather ^a   Ma, Yun ^a   Baum, Harold ^b   Mieli Vergani, Giorgina ^a   Vergani, Diego ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Autoantibody; Autoimmunity; Hepatitis B virus; Multiple sclerosis; Vaccination

Indexed keywords

AMINO ACID; AUTOANTIBODY; AUTOANTIGEN; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; MYELIN; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE;

ADULT; AMINO ACID ANALYSIS; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DEMYELINATING DISEASE; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MOLECULAR MIMICRY; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; SERUM; VACCINATION;

ADULT; AMINO ACID SEQUENCE; CROSS REACTIONS; FEMALE; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HUMANS; MALE; MIDDLE AGED; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; MYELIN-ASSOCIATED GLYCOPROTEIN; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 32144459543     PISSN: 17402522     EISSN: None     Source Type: Journal    
DOI: 10.1080/17402520500285247     Document Type: Article

References (39)

1. Aron-Maor A, Shoenfeld Y. 2001. Vaccination and systemic lupus erythematosus: The bidirectional dilemmas. Lupus 10:237-240.
2. Ascherio A, Zhang SM, Hernan MA, Olek MJ, Coplan PM, Brodovicz K, Walker AM. 2001. Hepatitis B vaccination and the risk of multiple sclerosis. N Engl J Med 344:327-332.
3. Bogdanos DP, Mieli-Vergani G, Vergani D. 2000. Virus, liver and autoimmunity. Dig Liver Dis 32:440-446.
4. Bogdanos DP, Choudhuri K, Vergani D. 2001. Molecular mimicry and autoimmune liver disease: Virtuous intentions, malign consequences. Liver 21:225-232.
5. Bogdanos DP, Baum H, Grasso A, Okamoto M, Butler P, Ma Y, Rigopoulou E, Bogdanos DP, Baum H, Sharma UC, Grasso A, Ma Y, Burroughs AK, Vergani D. 2002. Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis. J Hepatol 36:14-21.
6. Bogdanos DP, Baum H, Grasso A, Okamoto M, Butler P, Ma Y, Rigopoulou E, Montalto P, Davies ET, Burroughs AK, Vergani D. 2004a. Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis. J Hepatol 40: 31-9.
7. Bogdanos DP, Baum H, Gunsar F, Arioli D, Polymeros D, Ma Y, Burroughs AK, Vergani D. 2004b. Extensive homology between the major immunodominant mitochondrial antigen in primary biliary cirrhosis and Helicobacter pylori does not lead to immunological cross-reactivity. Scand J Gastroenterol 39: 981-987.
8. Bogdanos DP, Baum H, Okamoto M, Montalto P, Sharma UC, Rigopoulou EI, Vlachogiannakos J, Ma Y, Burroughs AK, Vergani D. 2005. Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its lactobacillus mimic. Hepatology 42:458-465.
9. Cohen AD, Shoenfeld Y. 1996. Vaccine-induced autoimmunity. J Autoimmun 9:699-703.
10. Confavreux C, Suissa S, Saddier P, Bourdes V, Vukusic S. 2001. Vaccinations and the risk of relapse in multiple sclerosis. Vaccines in multiple sclerosis study group. N Engl J Med 344:319-326.
11. Devaux B, Enderlin F, Wallner B, Smilek DE. 1997. Induction of EAE in mice with recombinant human MOG, and treatment of EAE with a MOG peptide. J Neuroimmunol 75:169-173.
12. Dyrberg T, Oldstone MB. 1986. Peptides as probes to study molecular mimicry and virus-induced autoimmunity. Curr Top Microbiol Immunol 130:25-37.
13. Geier MR, Geier DA. 2001. Immunologic reactions and hepatitis B vaccine. Ann Intern Med 134:1155.
14. Genain CP, Cannella B, Hauser SL, Raine CS. 1999. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat Med 5:170-175.
15. Girard M. 2005. Autoimmune hazards of hepatitis B vaccine. Autoimmun Rev 4:96-100.
16. Herroelen L, de Keyser J, Ebinger G. 1991. Central-nervous-system demyelination after immunisation with recombinant hepatitis B vaccine. Lancet 338:1174-1175.
17. Kerkar N, Choudhuri K, Ma Y, Mahmoud A, Bogdanos DP, Muratori L, Bianchi F, Williams R, Mieli-Vergani G, Vergani D. 2003. Cytochrome P4502D6(193-212): A new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease. J Immunol 170:1481-1489.
18. Landschulz WH, Johnson PF, McKnight SL. 1988. The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins. Science 240:1759-1764.
19. Maillefert JF, Sibilia J, Toussirot E, Vignon E, Eschard JP, Lorcerie B, Juvin R, Parchin-Geneste N, Piroth C, Wendling D, Kuntz JL, Tavernier C, Gaudin P. 1999. Rheumatic disorders developed after hepatitis B vaccination. Rheumatology (Oxford) 38: 978-983.
20. Marshall E. 1998. A shadow falls on hepatitis B vaccination effort. Science 281:630-631.
21. Martin R, McFarland HF, McFarlin DE. 1992. Immunological aspects of demyelinating diseases. Annu Rev Immunol 10:153-187.
22. Montalto P, Davies ET, Burroughs AK, Vergani D. 2004a. Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis. J Hepatol 40:31-39.
23. Oldstone MB. 1989. Molecular mimicry as a mechanism for the cause and a probe uncovering etiologic agent(s) of autoimmune disease. Curr Top Microbiol Immunol 145:127-135.
24. Oldstone MB. 1998. Molecular mimicry and immune-mediated diseases. Faseb J 12:1255-1265.
25. Oldstone MB. 1987. Molecular mimicry and autoimmune disease. Cell 50:819-820.
26. Poirriez J. 2004. A preliminary experiment of absorption of antinuclear antibodies by the hepatitis B vaccine components, in a case of neurolupus. Vaccine 22:3166-3168.
27. Quaratino S, Thorpe CJ, Travers PJ, Londei M. 1995. Similar antigenic surfaces, rather than sequence homology, dictate T-cell epitope molecular mimicry. Proc Natl Acad Sci USA 92:10398-10402.
28. Raine CS, Bornstein MB. 1970. Experimental allergic encephalomyelitis: a light and electron microscope study of remyelination and "sclerosis" in vitro. J Neuropathol Exp Neurol 29:552-574.
29. Ravel G, Christ M, Horand F, Descotes J. 2004. Autoimmunity, environmental exposure and vaccination: Is there a link? Toxicology 196:211-216.
30. Selmi C, Battezzati PM, Gershwin ME, Tishler M, Shoenfeld Y. 2005. Vaccines in the 21st century: The genetic response and the innocent bystander. Autoimmun Rev 4:79-81.
31. Shoenfeld Y, Aron-Maor A. 2000. Vaccination and autoimmunity- 'vaccinosis': A dangerous liaison? J Autoimmun 14:1-10.
32. Shouval D. 2003. Hepatitis B vaccines. J Hepatol 39(Suppl. 1): S70-S76.
33. Sloan-Lancaster J, Allen PM. 1996. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu Rev Immunol 14:1-27.
34. Steinman L. 1996. Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system. Cell 85:299-302.
35. Van de Water J, Ishibashi H, Coppel RL, Gershwin ME. 2001. Molecular mimicry and primary biliary cirrhosis: Premises not promises. Hepatology 33:771-775.
36. Vital C, Vital A, Gbikpi-Benissan G, Longy-Boursier M, Climas MT, Castaing Y, Canron MH, Le Bras M, Petry K. 2002. Postvaccinal inflammatory neuropathy: Peripheral nerve biopsy in 3 cases. J Peripher Nerv Syst 7:163-167.
37. Wekerle H. 1999. Remembering MOG: autoantibody mediated demyelination in multiple sclerosis? Nat Med 5:153-154.
38. Wucherpfennig KW 2001. Mechanisms for the induction of autoimmunity by infectious agents. J Clin Invest 108: 1097-1104.
39. von Herrath MG, Fujinami RS, Whitton JL. 2003. Microorganisms and autoimmunity: Making the barren field fertile? Nat Rev Microbiol 1:151-157.