Low-dose thalidomide-induced agranulocytosis in a multiple myeloma patient treated at diagnosis

Leukemia and Lymphoma

Volumn 46, Issue 12, 2005, Pages 1837-1838

  Mazzotta, Serena ^a   Gozzetti, Alessandro ^a,b   Pirrotta, Maria Teresa ^a   Bocchia, Monica ^a   Sammassimo, Simona ^a   Bucalossi, Alessandro ^a   Lauria, Francesco ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY HOSPITAL OF SIENA   (Italy)

Author keywords

Multiple myeloma; Neutropenia; Septicemia; Thalidomide

Indexed keywords

ANTIBIOTIC AGENT; DEXAMETHASONE; GRANULOCYTE COLONY STIMULATING FACTOR; THALIDOMIDE;

AGED; AGRANULOCYTOSIS; BONE PAIN; CASE REPORT; DRUG INDUCED DISEASE; DRUG WITHDRAWAL; FEBRILE NEUTROPENIA; FEMALE; HUMAN; HYPERCALCEMIA; KIDNEY FAILURE; LEUKOPENIA; LOW DRUG DOSE; MULTIPLE MYELOMA; MUSCLE WEAKNESS; NEUTROPENIA; PRIORITY JOURNAL; REVIEW; SEPTICEMIA;

AGED; AGRANULOCYTOSIS; ANTINEOPLASTIC AGENTS; FEMALE; HUMANS; LEUKOCYTE COUNT; MULTIPLE MYELOMA; THALIDOMIDE; TREATMENT OUTCOME;

EID: 32144447592     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190500237450     Document Type: Review

References (8)

1. Cavenagh, J and Oakervee, H. (2003) Thalidomide in multiple myeloma: current status and future prospects Br J Haematol, 120, pp. 18 - 26.
2. Cavo, M and Zamagni, E and Tosi, P and Cellini, C and Cangini, D and Tacchetti, P and (2004) First-line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma Haematologica, 89, pp. 826 - 831.
3. Singhal, S and Mehta, J and Desikan, R and Ayers, D and Roberson, P and Eddlemon, P and (1999) Antitumor activity of thalidomide in refractory multiple myeloma N Engl J Med, 341, pp. 1565 - 1571.
4. Hattori, Y and Kakimoto, T and Okamoto, S and Sato, N and Ikeda, Y. (2004) Thalidomide-induced severe neutropenia during treatment of multiple myeloma Int J Hematol, 79, pp. 283 - 288.
5. Rajkumar, S and Dispenzieri, A and Fonseca, R and Lacy, M and Geyer, S and Lust, J and (2001) Thalidomide for previously untreated indolent or smoldering multiple myeloma Leukemia, 15, pp. 1274 - 1276.
6. Koc, S and Leisenring, W and Flowers, M and Anasetti, C and Deeg, H and Nash, R and (2000) Thalidomide for treatment of patients with chronic graft-vs.-host disease Blood, 96, pp. 3995 - 3996.
7. Parker, P and Chao, N and Nademanee, A and O'Donnell, M and Schmidt, G and Snyder, D and (1995) Thalidomide as a salvage therapy for chronic graft-vs.-host disease Blood, 86, pp. 3604 - 3609.
8. Richardson, P and Schlossman, R and Weller, E and Hideshima, T and Mitsiades, C and Davies, F and (2002) Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma Blood, 100, pp. 3063 - 3067.