Association of indoor nitrogen dioxide exposure with respiratory symptoms in children with asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 173, Issue 3, 2006, Pages 297-303

  Belanger, Kathleen ^a,b   Gent, Janneane F ^a   Triche, Elizabeth W ^a   Bracken, Michael B ^a   Leaderer, Brian P ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

Asthma; Children; Gas stoves; Indoor environment; Nitrogen dioxide; Respiratory symptoms

Indexed keywords

NITROGEN DIOXIDE;

AGE DISTRIBUTION; ARTICLE; ASTHMA; CHEST TIGHTNESS; CHILD; CONFIDENCE INTERVAL; CONTROLLED STUDY; COUGHING; DISEASE ASSOCIATION; DYSPNEA; ENVIRONMENTAL EXPOSURE; ETHNOLOGY; FEMALE; HOME; HOUSING; HUMAN; INTERVIEW; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SAMPLING; SEASON; SOCIAL STATUS; STATISTICAL SIGNIFICANCE; SYMPTOM; TUBE; WHEEZING;

AIR POLLUTION, INDOOR; ASTHMA; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; HOUSEHOLD ARTICLES; HOUSING; HUMANS; INHALATION EXPOSURE; MALE; NITROGEN DIOXIDE; OXIDANTS, PHOTOCHEMICAL; RESPIRATION DISORDERS;

EID: 32144445230     PISSN: 1073449X     EISSN: 1073449X     Source Type: Journal    
DOI: 10.1164/rccm.200408-1123OC     Document Type: Article

References (45)

1. U.S. Census Bureau. 2000 census of population and housing. Summary File 3; Table H40: House Heating Fuel. Available from: http://fact.nder.census.gov.
2. Utell M, Frampton MW. Oxides of nitrogen. In: Roth RA, editor. Comprehensive toxicology: oxides of nitrogen. Cambridge, UK: Cambridge University Press; 1997. pp. 303-312.
3. Samet JM, Utell MJ. The risk of nitrogen dioxide: what have we learned from epidemiological and clinical studies? Toxicol Ind Health 1990;6:247-262.
4. Basu R, Samet JM. A review of the epidemiological evidence on health effects of nitrogen dioxide exposure from gas stoves. J Environ Med 1999;1:173-187.
5. Nitschke M, Smith BJ, Pilotto LS, Pisaniello DL, Abramson MJ, Ruffin RE. Respiratory health effects of nitrogen dioxide exposure and current guidelines. Int J Environ Health Res 1999;9:39-53.
6. Fuhlbrigge A, Weiss S. Domestic gas appliances and lung disease. Thorax 1997;52:S58-S62.
7. Chauhan AJ. Gas cooking appliances and indoor pollution. Clin Exp Allergy 1999;29:1009-1013.
8. Jarvis D. Gas cooking and respiratory disease. Thorax 1999;54:1054.
9. Strachan DP. The role of environmental factors in asthma. BMJ 2000;56:865-882.
10. Brunekreef B. NO2: the gas that won't go away. Clin Exp Allergy 2001;31: 1170-1172.
11. Samet JM, Bell ML. Commentary: nitrogen dioxide and asthma redux. Int J Epidemiol 2004;33:215-216.
12. Hasselblad V, Eddy D, Kotchmar D. Synthesis of environmental evidence: nitrogen dioxide epidemiology studies. J Air Waste Manag Assoc 1992;42:662-671.
13. Mukala K, Alm S, Tiittanen P, Salonen RO, Jantunen M, Pekkanen J. Nitrogen dioxide exposure assessment and cough among preschool children. Arch Env Health 2000;55:431-438.
14. Shima M, Adachi M. Effect of outdoor and indoor nitrogen dioxide on respiratory symptoms in schoolchildren. Int J Epidemiol 2000;29:862-870.
15. Ponsonby A-L, Glasgow N, Gatenby P, Mullins R, McDonald AD, Hurwitz M, Pradith B, Attewell R. The relationship between low level nitrogen dioxide exposure and child lung function after cold air challenge. Clin Exp Allergy 2001;31:1205-1212.
16. Samet JM, Lambert WE, Skipper BJ, Cushing AH, Hunt WC, Young SA, McLaren LC, Schwab M, Spengler JD. Nitrogen dioxide and respiratory illness in infants. Am Rev Respir Dis 1993;148:1258-1265.
17. Magnus P, Nafstad P, Oie L, Carlsen KCL, Becher G, Kongerud J, Carlsen K-H, Samuelson SO, Botten G, Bakketeig L. Exposure to nitrogen dioxide and the occurrence of bronchial obstruction in children below 2 years. Int J Epidemiol 1998;27:995-999.
18. Sunyer J, Puig C, Torrent M, Garcia-Algar O, Calico I, Munoz-Ortiz L, Barnes M, Cullinan P. Nitrogen dioxide is not associated with respiratory infection during the first year of life. Int J Epidemiol 2004;33:116-120.
19. Emenius G, Svartengren M, Korsgaard J, Nordvall L, Pershagen G, Wickman M. Building characteristics, indoor air quality and recurrent wheezing in very young children (BAMSE). Indoor Air 2004;14:34-42.
20. Smith BJ, Nitschke M, Pilotto LS, Ruffin RE, Pisaniello DL, Wilson KJ. Health effects of daily indoor nitrogen dioxide exposure in people with asthma. Eur Respir J 2000;16:879-885.
21. Linaker CH, Coggon D, Holgate ST, Clough J, Josephs L, Chauhan AJ, Inskip HM. Personal exposure to nitrogen dioxide and risk of airflow obstruction in asthmatic children with upper respiratory infection. Thorax 2000;55:930-933.
22. 2) and the severity of virus-induced asthma in children. Lancet 2003;361:1939-1944.
23. Pilotto LS, Nitschke M, Smith BJ, Pisaniello D, Ruffin RE, McElroy HJ, Martin J, Hiller JE. Randomized controlled trial of unflued gas heater replacement on respiratory health of asthmatic schoolchildren. Int J Epidemiol 2003;33:208-214.
24. Belanger K, Beckett W, Triche E, Bracken M, Holford T, Ren P, McSharry J-E, Gold D, Platts-Mills T, Leaderer B. Symptoms of wheeze and persistent cough in the first year of life: associations with indoor allergens, air contaminants and maternal history of asthma. Am J Epidemiol 2003;158:195-202.
25. 2 and nitrous acid and respiratory symptoms in the first year of life. Epidemiology 2004;15:471-478.
26. Berglund M. Health risk evaluation of nitrogen oxides: exposure. Scand J Work Environ Health 1993;19:37-43.
27. Bauer MA, Utell MJ, Morrow PE, Speers DM, Gibb FR. Inhalation of 0.30 ppm nitrogen dioxide potentiates exercise-induced bronchospasm in asthmatics. Am Rev Respir Dis 1986;134:1203-1208.
28. Folinsbee LJ. Does nitrogen dioxide exposure increase airways responsiveness? Toxicol Ind Health 1992;8:273-283.
29. Gent JF, Ren P, Belanger K, Triche E, Bracken MB, Holford TR, Leaderer BP. Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthma. Environ Health Perspect 2002;110:A781-A786.
30. Gent JF, Belanger K, Triche EW, Holford TR, Beckett WS, Bracken MB, Leaderer BP. Respiratory symptoms and indoor nitrogen dioxide: a retrospective study of 682 asthmatic children [abstract]. Am J Respir Crit Care Med 2004;170:A162.
31. Palmes ED, Gunnison AF, DiMattio J, Tomczyk C. Personal sampler for nitrogen dioxide. Am Ind Hyg Assoc J 1976;37:570-577.
32. Breysse PN, Buckley TJ, Williams D, Beck CM, Jo S-J, Merriman B, Kanchanaraksa S, Swartz LJ, Callahan KA, Butz AM, et al. Indoor exposures to air pollutants and allergens in the homes of asthmatic children in inner-city Baltimore. Environ Res 2005;95:167-176.
33. Brunekreef B, Noy D, Clausing P. Variability of exposure measurements in environmental epidemiology. Am J Epidemiol 1987;125:892-898.
34. Spengler JD, Schwab M, McDermott A, Lambert WE, Samet JM. Research report: nitrogen dioxide and respiratory illness in children. Part IV: effects of housing and meteorologic factors on indoor nitrogen dioxide concentrations. Res Rep Health Eff Inst 1996; Dec (58):1-29; discussion 31-36.
35. 3 levels in panel studies. Environ Res 1999;81:339-348.
36. Leaderer B, Zagraniski R, Berwick M, Stolwijk J. Assessment of exposure to indoor air contaminants from combustion sources: methodology and application. Am J Epidemiol 1986;124:275-289.
37. Hoek G, Brunekreef B, Meijer R, Scholten A, Boleij J. Indoor nitrogen dioxide pollution and respiratory symptoms of schoolchildren. Int Arch Occup Environ Health 1984;55:79-86.
38. Levy JI, Lee K, Spengler JD, Yanagisawa Y. Impact of residential nitrogen dioxide exposure on personal exposure: an international study. J Air Waste Manag Assoc 1998;48:553-560.
39. Linaker CH, Chauhan AJ, Inskip HM, Holgate ST, Coggon D. Personal exposures of children to nitrogen dioxide relative to concentrations in outdoor air. Occup Environ Med 2000;57:472-476.
40. Dekker C, Dales R, Bartlett S, Brunekreef B, Zwanenburgy H. Childhood asthma and the indoor environment. Chest 1991;100:922-926.
41. Kuhr J, Hendel Kramer A, Karmaus W, Moseler M, Weiss K, Stephan V, Urbanek R. Air pollutant burden and bronchial asthma in school children. Soz Prav Med 1991;36:67-73.
42. Volkmer RE, Ruffin RE, Wigg NR, Davies N. The prevalence of respiratory symptoms in South Australian preschool children. II Factors associated with indoor air quality. J Paediatr Child Health 1995;31:116-120.
43. Garrett MH, Hooper MA, Hooper BM, Abramson MJ. Respiratory symptoms in children and indoor exposure to nitrogen dioxide and gas stoves. Am J Respir Crit Care Med 1998;158:891-895.
44. World Health Organization. Air quality guidelines for Europe, 2nd ed. Copenhagen: World Health Organization; 2000.
45. U.S. Environmental Protection Agency. National ambient air quality standards (naaqs). Updated July 29, 2005. Available online at http:// epa.gov/air/criteria.html [accessed December 12, 2005.]