Enantiospecific separation and quantisation of mephenytoin and its metabolites nirvanol and 4′-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 20, Issue 3, 2006, Pages 463-472

  Jansson, Britt ^a,b   Elsherbiny, Doaa ^a   Simonsson, Ulrika S H ^a  

^a Biomedicum   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

CONCENTRATION RANGES; ENANTIOSPECIFIC; HUMAN PLASMAS; HUMAN URINE; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; QUANTISATION; SENSITIVE METHOD; TANDEM MASS;

METABOLITES;

4 HYDROXYMEPHENYTOIN; 4-HYDROXYMEPHENYTOIN; DRUG DERIVATIVE; MEPHENYTOIN; NORMEPHENYTOIN;

ARTICLE; BLOOD; CHEMISTRY; HUMAN; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STANDARD; STEREOISOMERISM; URINE;

CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; MEPHENYTOIN; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM;

EID: 32044456194     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.2324     Document Type: Article

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