Mixl1 and Oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells

Stem Cells and Development

Volumn 14, Issue 6, 2005, Pages 656-663

  Mossman, Anna K ^a   Sourris, Koula ^a   Ng, Elizabeth ^a   Stanley, Edouard G ^a   Elefanty, Andrew G ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN MIX11; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; EMBRYO CELL; ENDODERM; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL CELL; MESODERM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL DIFFERENTIATION; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; EMBRYO; HOMEODOMAIN PROTEINS; HUMANS; MICE; OCTAMER TRANSCRIPTION FACTOR-3; STEM CELLS;

ANIMALIA; MAMMALIA;

EID: 32044453122     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2005.14.656     Document Type: Article

References (24)

1. Smith AG. (2001). Embryo-derived stem cells: of mice and men. Annu Rev Cell Dev Biol 17:435-462.
2. Chambers I and A Smith. (2004). Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 23:7150-7160.
3. Pesce M and HR Scholer. (2001). Oct-4: gatekeeper in the beginnings of mammalian development. Stem Cells 19:271-278.
4. Rogers MB, BA Hosier and LJ Gudas. (1991). Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes. Development 113:815-824.
5. Mitsui K, Y Tokuzawa, H Itoh, K Segawa, M Murakami, K Takahashi, M Maruyama, M Maeda and S Yamanaka. (2003). The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113:631-642.
6. Chambers I, D Colby, M Robertson, J Nichols, S Lee, S Tweedie and A Smith. (2003). Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113:643-655.
7. Ng ES, L Azzola, K Sourris, L Robb, EG Stanley and AG Elefanty. (2005). The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells. Development 132:873-884.
8. Nichols J, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, I Chambers, H Scholer and A Smith. (1998). Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95:379-391.
9. Niwa H, J Miyazaki and AG Smith. (2000). Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nature Genet 24:372-376.
10. Scholer HR, GR Dressier, R Balling, H Rohdewohld and P Grass. (1990) Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J 9:2185-2195.
11. Hart AH, L Hartley, K Sourris, ES Stadler, R Li, EG Stanley, PP Tam, AG Elefanty and L Robb. (2002). Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development 129:3597-3608.
12. Robb L, L Hartley, CG Begley, TC Brodnicki, NG Copeland, DJ Gilbert, NA Jenkins and AG Elefanty. (2000). Cloning, expression analysis, and chromosomal localization of murine and human homologues of a Xenopus mix gene. Dev Dyn 219:497-504.
13. Pearce JJ and MJ Evans. (1999). Mml, a mouse Mix-like gene expressed in the primitive streak. Mech Dev 87:189-192.
14. Mohn D, SW Chen, DC Dias, DC Weinstein, MA Dyer, K Sahr, CE Ducker, E Zahradka, G Keller, KS Zaret, LJ Gudas and MH Baron. (2003). Mouse Mix gene 16 is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Dev Dyn 226:446-459.
15. Kubo A, K Shinozaki, JM Shannon, V Kouskoff, M Kennedy, S Woo, HJ Fehling and G Keller. (2004). Development of definitive endoderm from embryonic stem cells in culture. Development 131:1651-1662.
16. Mizushima S and S Nagata. (1990). pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res 18:5322.
17. Leavitt J, P Gunning, P Porreca, SY Ng, CS Lin and L Kedes. (1984). Molecular cloning and characterization of mutant and wild-type human beta-actin genes. Mol Cell Biol 4:1961-1969.
18. Amit M, MK Carpenter, MS Inokuma, CP Chiu, CP Harris, MA Waknitz, J Itskovitz-Eldor and JA Thomson. (2000). Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev Biol 227:271-278.
19. Ng ES, RP Davis, L Azzola, EG Stanley and AG Elefanty. (2005). Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation. Blood 106:1601-1603.
20. Lengsfeld AM, I Low, T Wieland, P Dancker and W Hasselbach. (1974). Interaction of phalloidin with actin. Proc Natl Acad Sci USA 71:2803-2807.
21. Osborn L, S Kunkel and GJ Nabel. (1989). Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proc Natl Acad Sci USA 86:2336-2340.
22. Rosa FM. (1989) Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. Cell 57:965-974.
23. Anderson R, TK Copeland, H Scholer, J Heasman and C Wylie. (2000). The onset of germ cell migration in the mouse embryo. Mech Dev 91:61-68.
24. Palmieri SL, W Peter, H Hess and HR Scholer. (1994). Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol 166:259-267.