The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin

European Journal of Pharmacology

Volumn 531, Issue 1-3, 2006, Pages 87-95

  Mixcoatl Zecuatl, Teresa ^a   Flores Murrieta, Francisco J ^b,c   Granados Soto, Vinicio ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^c SECRETARÍA DE SALUD   (Mexico)

Author keywords

Diazoxide; Gabapentin; Guanylyl cyclase; K+ channel opener; Neuropathic pain; Nitric oxide; Pinacidil; Protein kinase G

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 7 NITROINDAZOLE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; APAMIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; DIAZOXIDE; GABAPENTIN; GLIBENCLAMIDE; GUANYLATE CYCLASE INHIBITOR; KT 5823; MARGATOXIN; N(G) NITRO DEXTRO ARGININE METHYL ESTER; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; VOLTAGE GATED POTASSIUM CHANNEL;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG MECHANISM; DRUG SPECIFICITY; ENZYME ACTIVATION; FEMALE; NONHUMAN; PRIORITY JOURNAL; RAT;

AMINES; ANALGESICS; ANIMALS; APAMIN; CARBAZOLES; CHARYBDOTOXIN; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; CYCLOHEXANECARBOXYLIC ACIDS; DIAZOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLYBURIDE; INDAZOLES; INDOLES; INJECTIONS, SPINAL; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OKADAIC ACID; OXADIAZOLES; PAIN; PINACIDIL; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; PROTEIN KINASE INHIBITORS; QUINOXALINES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SPINAL NERVES; STEREOISOMERISM; TIME FACTORS; VASODILATOR AGENTS;

EID: 32044449385     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.12.006     Document Type: Article

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