Inhibition of target of rapamycin signaling by rapamycin in the unicellular green alga Chlamydomonas reinhardtii

Plant Physiology

Volumn 139, Issue 4, 2005, Pages 1736-1749

  Crespo, José L ^a   Díaz Troya, Sandra ^a   Florencio, Francisco J ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALGAE; CELLS; PHOTOSYNTHESIS; PLANTS (BOTANY);

CHLAMYDOMONAS; PHOTOSYNTHETIC EUKARYOTES; RAPAMYCIN; TOR SIGNALING;

ENZYMES;

ALGAE; CELLS; ENZYMES; PHOTOSYNTHESIS; PLANTS;

ALGAE; ARABIDOPSIS; ARABIDOPSIS THALIANA; CHLAMYDOMONAS; CHLAMYDOMONAS REINHARDTII; CHLOROPHYTA; EUKARYOTA;

ALGAL DNA; ALGAL PROTEIN; CELL CYCLE PROTEIN; COMPLEMENTARY DNA; FK 506 BINDING PROTEIN; PROTOZOAL DNA; PROTOZOAL PROTEIN; RAPAMYCIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CHLAMYDOMONAS REINHARDTII; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PHYLOGENY; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ALGAL PROTEINS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; CHLAMYDOMONAS REINHARDTII; CLONING, MOLECULAR; CONSERVED SEQUENCE; DNA, ALGAL; DNA, COMPLEMENTARY; DNA, PROTOZOAN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHYLOGENY; PROTOZOAN PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SIROLIMUS; TACROLIMUS BINDING PROTEIN 1A;

EID: 32044445379     PISSN: 00320889     EISSN: None     Source Type: Journal    
DOI: 10.1104/pp.105.070847     Document Type: Article

References (50)

1. Aghdasi B, Ye K, Resnick A, Huang A, Ha HC, Guo X, Dawson TM, Dawson VL, Snyder SH (2001) FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle. Proc Natl Acad Sci USA 98: 2425-2430
2. Barbet NC, Schneider U, Helliwell SB, Stansfield I, Tuite MF, Hall MN (1996) TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell 7: 25-42
3. Beck T, Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402: 689-692
4. Bjornsti MA, Houghton PJ (2004) The TOR pathway: a target for cancer therapy. Nat Rev Cancer 4: 335-348
5. Brillantes AB, Ondrias K, Scott A, Kobrinsky E, Ondriasova E, Moschella MC, Jayaraman T, Landers M, Ehrlich BE, Marks AR (1994) Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein. Cell 77: 513-523
6. Choi J, Chen J, Schreiber SL, Clardy J (1996) Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. Science 273: 239-242
7. Crespo JL, Hall MN (2002) Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae. Microbiol Mol Biol Rev 66: 579-591
8. Crespo JL, Powers T, Fowler B, Hall MN (2002) The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine. Proc Natl Acad Sci USA 99: 6784-6789
9. Dolinski K, Muir S, Cardenas M, Heitman J (1997) All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 94: 13093-13098
10. Falciatore A, Merendino L, Barneche F, Ceol M, Meskauskiene R, Apel K, Rochaix JD (2005) The FLP proteins act as regulators of chlorophyll synthesis in response to light and plastid signals in Chlamydomonas. Genes Dev 19: 176-187
11. Faure JD, Gingerich D, Howell SH (1998) An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506. Plant J 15:783-789
12. Fruman DA, Burakoff SJ, Bierer BE (1994) Immunophilins in protein folding and immunosuppression. FASEB J 8: 391-400
13. Guex N, Diemand A, Peitsch MC (1999) Protein modelling for all. Trends Biochem Sci 24: 364-367
14. Guttenberger M (2000) Arbuscules of vesicular-arbuscular mycorrhizal fungi inhabit an acidic compartment within plant roots. Planta 211: 299-304
15. Harris EH (1989) The Chlamydomonas Sourcebook. Academic Press, San Diego
16. He Z, Li L, Luan S (2004) Immunophilins and parvulins: superfamily of peptidyl prolyl isomerases in Arabidopsis. Plant Physiol 134: 1243-1267
17. Heitman J, Mowa NR, Hall MN (1991) Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253: 905-909
18. Inoki K, Ouyang H, Li Y, Guan KL (2005) Signaling by target of rapamycin proteins in cell growth control. Microbiol Mol Biol Rev 69: 79-100
19. Jacinto E, Loewith R, Schmidt A, Lin S, Ruegg MA, Hall A, Hall MN (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 6: 1122-1128
20. Johnston M, Davis RW (1984) Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol 4: 1440-1443
21. Kindle KL (1998) Nuclear transformation: technology and applications. In JD Rochaix, M Goldschmidt-Clermont, S Merchant, eds, The Molecular Biology of Chloroplast and Mitochondria in Chlamydomonas. Kluwer Academic Publishers, Dordrecht, The Netherlands, pp 41-61
22. Koltin Y, Faucette L, Bergsma DJ, Levy MA, Cafferkey R, Koser PL, Johnson RK, Livi GP (1991) Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein. Mol Cell Biol 11: 1718-1723
23. Komine Y, Eggink LL, Park H, Hoober JK (2000) Vacuolar granules in Chlamydomonas reinhardtii: polyphosphate and a 70-kDa polypeptide as major components. Planta 210: 897-905
24. Kunz J, Henriquez R, Schneider U, Deuter-Reinhard M, Movva NR, Hall MN (1993) Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell 73: 585-596
25. Kuo CJ, Chung J, Fiorentino DF, Flanagan WM, Blenis J, Crabtree GR (1992) Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature 358: 70-73
26. Menand B, Desnos T, Nussaume L, Berger F, Bouchez D, Meyer C, Robaglia C (2002) Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene. Proc Natl Acad Sci USA 99: 6422-6427
27. Ohsumi Y (2001) Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2: 211-216
28. Perzov N, Padler-Karavani V, Nelson H, Nelson N (2002) Characterization of yeast V-ATPase mutants lacking Vph1p or Stv1p and the effect on endocytosis. J Exp Biol 205: 1209-1219
29. Rochais JD, Mayfield S, Goldschmidt-aermont M, Erickson J (1987) Molecular biology of Chlamydomonas. In CH Shaw, ed, Plant Molecular Biology: A Practical Approach. IRL Press, Oxford, pp 253-275
30. Sager R, Palade GE (1957) Structure and development of the chloroplast in Chlamydomonas: the normal green cell. J Biophys Biochem Cytol 3: 463-488
31. Saitou N, Nei M (1987) The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4: 406-425
32. Sambrook J, Fritsch E, Maniatis T (1989) Molecular Cloning: A Laboratory Manual, Ed 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
33. Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM (2004) Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 14: 1296-1302
34. Schmelze T, Hall MN (2000) TOR, a central controller of cell growth. Cell 103: 253-262
35. Schreiber SL (1991) Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 251: 283-287
36. Schreiber SL (1992) Immunophilin-sensitive protein phosphatase action in cell signaling pathways. Cell 70: 365-368
37. Shamji AF, Kuruvilla FG, Schreiber SL (2000) Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins. Curr Biol 10: 1574-1581
38. Sherman F (1991) Getting started with yeast. Methods Enzymol 194: 3-21
39. Shou W, Aghdasi B, Armstrong DL, Guo Q, Bao S, Charng MJ, Mathews LM, Schneider MD, Hamilton SL, Matzuk MM (1998) Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12. Nature 391: 489-492
40. Sigal NH, Dumont FJ (1992) Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. Annu Rev Immunol 10: 519-560
41. Thompson AR, Vierstra RD (2005) Autophagic recycling: lessons from yeast help define the process in plants. Curr Opin Plant Biol 8: 165-173
42. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680
43. Vallon O (2005) Chlamydomonas immunophilins and parvulins: survey and critical assessment of gene models. Eukaryot Cell 4: 230-241
44. Vespa L, Vachon G, Berger F, Perazza D, Faure JD, Herzog M (2004) The immunophilin-interacting protein AtFIP37 from Arabidopsis is essential for plant development and is involved in trichome endoreduplication. Plant Physiol 134: 1283-1292
45. Vezina C, Kudelski A, Sehgal SN (1975) Rapamycin (AY-22,989), a new antifungal antibiotic: taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot (Tokyo) 28: 721-726
46. Wallace AC, Laskowski RA, Thornton JM (1995) LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. Protein Eng 8: 127-134
47. Wang T, Donahoe PK, Zervos AS (1994) Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12. Science 265: 674-676
48. Wang T, Li BY, Danielson PD, Shah PC, Rockwell S, Lechleider RJ, Martin J, Manganaro T, Donahoe PK (1996) The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors. Cell 86: 435-444
49. Weisman R, Choder M, Koltin Y (1997) Rapamycin specifically interferes with the developmental response of fission yeast to starvation. J Bacteriol 179: 6325-6334
50. Xu Q, Liang S, Kudla J, Luan S (1998) Molecular characterization of a plant FKBP12 that does not mediate action of FK506 and rapamycin. Plant J 15: 511-519