Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: A review

Cutis

Volumn 77, Issue 1 SUPPL., 2006, Pages 11-16

  Niren, Neil M ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN A; NICOTINAMIDE; ZINC;

ACNE VULGARIS; BULLOUS SKIN DISEASE; DRUG COMBINATION; HUMAN; IMMUNOLOGY; REVIEW; ROSACEA;

ACNE VULGARIS; ANTI-INFLAMMATORY AGENTS; DRUG COMBINATIONS; HUMANS; IMMUNOGLOBULIN A; NIACINAMIDE; ROSACEA; SKIN DISEASES, VESICULOBULLOUS; ZINC;

EID: 31944451377     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (24)

1. Matts PJ, Oblong JE, Bissett DL. A review of the range of effects of niacinamide in human skin. IFSCC Magazine. 2002;5:285-289.
2. Fivenson DP. The mechanisms of action of nicotinamide and zinc in inflammatory skin disease. Cutis. 2006;77(suppl 1):5-10.
3. Griffiths CEM. Nicotinamide 4% gel for the treatment of inflammatory acne vulgaris. J Dermatol Treat. 1995;6(suppl 1):S8-S10.
4. Shalita AR, Smith JG, Parish LC, et al. Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. Int J Dermatol. 1995;34:434-437.
5. Weltert Y, Chartier S, Gibaud C, et al. Double-blind clinical assessment of the efficacy of a 4% nicotinamide gel (Exfoliac NC gel) versus a 4% erythromycin gel in the treatment of moderate acne with predominant inflammatory component. Nouv Dermatol. 2004;23:385-394.
6. Jablonska S. Treatment of acne vulgaris and rosacea [letter]. Arch Dermatol. 1975;111:929.
7. Niren NM, Torok HM. The Nicomide Improvement in Clinical Outcomes Study (NICOS): results of an 8-week trial. Cutis. 2006;77(suppl 1):17-28.
8. Berk MA, Lorincz AL. The treatment of bullous pemphigoid with tetracycline and niacinamide. a preliminary report. Arch Dermatol 1986;122:670-674.
9. Fivenson DP, Breneman DL, Rosen GB, et al. Nicotinamide and tetracycline therapy of bullous pemphigoid. Arch Dermatol. 1994;130:753-758.
10. Kolbach DN, Remme JJ, Bos WH, et al. Bullous pemphigoid successfully controlled by tetracycline and nicotinamide. Br J Dermatol. 1995;133:88-90.
11. Kawahara Y, Hashimoto T, Ohata Y, et al. Eleven cases of bullous pemphigoid treated with a combination of minocycline and nicotinamide. Eur J Dermatol. 1996;6:427-429.
12. Homschuh B, Hamm H, Wever S, et al. Treatment of 16 patients with bullous pemphigoid with oral tetracycline and niacinamide and topical clobetasol. J Am Acad Dermatol. 1997;36:101-103.
13. Chaffins ML, Collison D, Fivenson DP. Treatment of pemphigus and linear IgA dermatosis with nicotinamide and tetracycline: a review of 13 cases. J Am Acad Dermatol. 1993;28:998-1000.
14. Poskitt L, Wojnarowska F. Treatment of cicatricial pemphigoid with tetracycline and nicotinamide. Clin Exp Dermatol. 1995;20:258-259.
15. Reiche L, Wojnarowska F, Mallon E. Combination therapy with nicotinamide and tetracyclines for cicatricial pemphigoid: further support for its efficacy. Clin Exp Dermatol. 1998;23:254-257.
16. Neumann R, Rappold E, Pohl-Markl H. Treatment of polymorphous light eruption with nicotinamide: a pilot study. Br J Dermatol. 1986;115:77-80.
17. Peoples D, Fivenson DP. Linear IgA bullous dermatosis: successful treatment with tetracycline and nicotinamide. J Am Acad Dermatol. 1992;26:498-499.
18. Handfield-Jones S, Jones S, Peachey R. High dose nicotinamide in the treatment of necrobiosis lipoidica. Br J Dermatol. 1988;118:693-696.
19. Fivenson DP, Kimbrough TL. Lichen planus pemphigoides: combination therapy with tetracycline and nicotinamide. J Am Acad Dermatol. 1997;36:638-640.
20. Zemtsov A, Neldner KH. Successful treatment of dermatitis herpetiformis with tetracycline and nicotinamide in a patient unable to tolerate dapsone. J Am Acad Dermatol. 1993;28:505-506.
21. Shah SA, Ormerod AD. Dermatitis herpetiformis effectively treated with heparin, tetracycline and nicotinamide. Clin Exp Dermatol. 2000;25:204-205.
22. Ma A, Medenica M. Response of generalized granuloma annulare to high-dose niacinamide. Arch Dermatol. 1983;119:836-839.
23. Kohler IK, Lorincz AL. Erythema elevatum diutinum treated with niacinamide and tetracycline. Arch Dermatol. 1980;116:693-695.
24. Nicomide (nicotinamide, zinc, copper, and folic acid) tablets [package insert]. Vernon Hills, Ill: Sirius Laboratories, Inc; 2003.