Improvement of cytomegalovirus avidity testing by adjusting the concentration of CMV-specific IgG in test samples

Journal of Clinical Virology

Volumn 35, Issue 3, 2006, Pages 303-309

  Dangel, Volker ^a   Bäder, Ursula ^a   Enders, Gisela ^a  

^a Infectious Diseases and Epidemology EV Labor Prof Enders and Partners   (Germany)

Author keywords

Avidity index (AI); CMV infection; Pregnancy; Sample pre dilution

Indexed keywords

CYTOMEGALOVIRUS ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY;

ANALYZER; ANTIBODY BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DILUTION; FEMALE; HUMAN; IMMUNOASSAY; IMMUNOGLOBULIN BLOOD LEVEL; PRIORITY JOURNAL; REPRODUCIBILITY; SEROLOGY; SERUM; VIRUS IDENTIFICATION;

ANTIBODIES, VIRAL; ANTIBODY AFFINITY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FALSE NEGATIVE REACTIONS; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; REPRODUCIBILITY OF RESULTS; SEROLOGIC TESTS;

EID: 31944435286     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2005.09.011     Document Type: Article

References (13)

1. M. Bodéus, D. Beulné, and P. Goubau Ability of three IgG avidity assays to exclude recent cytomegalovirus infection Clin Microbiol Infect Dis 20 2001 248 252
2. M. Bodéus, and P. Goubau Predictive value of maternal-IgG avidity for congenital human cytomegalovirus infection J Clin Virol 12 1999 3 8
3. M. Bodéus, M. Van Ranst, P. Bernard, C. Hubinont, and P. Goubau Anti-cytomegalovirus IgG avidity in pregnancy: a 2 year prospective study Fetal Diagn Ther 17 2002 362 366
4. A. Daiminger, U. Bäder, M. Eggers, T. Lazzarotto, and G. Enders Evaluation of two novel enzyme immunoassays using recombinant antigens to detect cytomegalovirus-specific immunoglobulin M in sera from pregnant women J Clin Virol 13 3 1999 161 171
5. A. Daiminger, U. Bäder, and G. Enders Pre- and periconceptional primary cytomegalovirus infection-risk of vertical transmission and congenital disease BJOG 112 2005 166 172
6. M. Eggers, C. Metzger, and G. Enders Differentiation between acute primary and recurrent human cytomegalovirus infection in pregnancy using a microneutralization assay J Med Virol 56 1998 351 358
7. M. Eggers, U. Bäder, and G. Enders Combination of microneutralization and avidity assays: improved diagnosis of recent primary human cytomegalovirus infection in single serum sample of second trimester pregnancy J Med Virol 60 2000 324 330
8. G. Enders, U. Bäder, U. Bartelt, and A. Daiminger Zytomegalovirus (CMV) Durchseuchung und Häufigkeit von CMV-Primärinfektionen bei schwangeren Frauen in Deutschland Bundesgesundheitsbl-Gesundheitsforsch- Gesundheitsschutz 46 2003 426 432
9. K.B. Fowler, S. Stagno, R.F. Pass, W.J. Britt, T.J. Boll, and C.A. Alford The outcome of congenital cytomegalovirus in relation to maternal antibody status N Engl J Med 326 1992 663 667
10. L. Grangerot-Keros, M.J. Mayaux, P. Lebon, F. Freymuth, G. Eugène, and R. Stricker Value of cytomegalovirus (CMV) IgG avidity index for the diagnosis of primary CMV infection in pregnant women J Infect Dis 175 1997 944 946
11. K. Hedman, M. Lappalainen, M. Söderlund, and L. Hedman Avidity of IgG in serodiagnosis of infectious diseases Rev Med Microbiol 4 1993 123 129
12. T. Lazzarotto, P. Spezzacatena, S. Varani, L. Gabrielli, P. Pradelli, and B. Guerra Anticytomegalovirus (anti CMV) immunglobulin G avidity in identification of pregnant women at risk of transmitting congenital CMV infection Clin Diagn Lab Immunol 6 1 1999 127 129
13. S. Stagno, R.F. Pass, G. Cloud, W.J. Britt, R.E. Henderson, and P.D. Walton Primary cytomegalovirus infection in pregnancy. Incidence, transmission to fetus and clinical outcome JAMA 256 1986 1904 1908