Exchange of lipooligosaccharide synthesis genes creates potential Guillain-Barré syndrome-inducible strains of Campylobacter jejuni

Infection and Immunity

Volumn 74, Issue 2, 2006, Pages 1368-1372

  Phongsisay, Vongsavanh ^a   Perera, Viraj N ^a   Fry, Benjamin N ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; GANGLIOSIDE GM1; LIPOOLIGOSACCHARIDE;

ARTICLE; BACTERIAL STRAIN; BACTERIUM TRANSFORMATION; CAMPYLOBACTER JEJUNI; CARBOHYDRATE SYNTHESIS; DISEASE ASSOCIATION; DNA STRUCTURE; GENE EXPRESSION REGULATION; GENETIC VARIABILITY; GUILLAIN BARRE SYNDROME; HUMAN; LIPOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL;

BACTERIAL PROTEINS; CAMPYLOBACTER JEJUNI; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; G(M1) GANGLIOSIDE; GENE TRANSFER, HORIZONTAL; GUILLAIN-BARRE SYNDROME; HUMANS; LIPOPOLYSACCHARIDES; MOLECULAR MIMICRY; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECOMBINATION, GENETIC; TRANSFORMATION, BACTERIAL;

EID: 31844450168     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.74.2.1368-1372.2006     Document Type: Article

References (18)

1. Alm, R. A., P. Guerry, and T. J. Trust. 1993. Significance of duplicated flagellin genes in Campylobacter. S. Mol. Biol. 230:359-363.
2. Boer, P., J. A. Wagenaar, R. P. Achterberg, J. P. Putten, L. M. Schouls, and B. Duim. 2002. Generation of Campylobacter jejuni genetic diversity in vivo. Mol. Microbiol. 44:351-359.
3. Fry, B. N., S. Feng, Y. Y. Chen, D. G. Newell, P. J. Coloe, and V. Korolik. 2000. The galE gene of Campylobacter jejuni is involved in lipopolysaccharide synthesis and virulence. Infect. Immun. 68:2594-2601.
4. Fry, B. N., V. Korolik, J. A. ten Brinke, M. T. Pennings, R. Zalm, B. J. Teunis, P. J. Coloe, and B. A. van der Zeijst. 1998. The lipopolysaccharide biosynthesis locus of Campylobacter jejuni 81116. Microbiology 144(Pt. 8):2049-2061.
5. Gilbert, M., P. C. Godschalk, M. F. Karwaski, C. W. Ang, A. van Belkum, J. Li, W. W. Wakarchuk, and H. P. Endtz. 2004. Evidence for acquisition of the lipooligosaccharide biosynthesis locus in Campylobacter jejuni GB11, a strain isolated from a patient with Guillain-Barre syndrome, by horizontal exchange. Infect. Immun. 72:1162-1165.
6. Gilbert, M., M. F. Karwaski, S. Bernatchez, N. M. Young, E. Taboada, J. Michniewicz, A. M. Cunningham, and W. W. Wakarchuk. 2002. The genetic bases for the variation in the lipo-oligosaccharide of the mucosal pathogen, Campylobacter jejuni. Biosynthesis of sialylated ganglioside mimics in the core oligosaccharide. J. Biol. Chem. 277:327-337.
7. Guerry, P., C. P. Ewing, T. E. Hickey, M. M. Prendergast, and A. P. Moran. 2000. Sialylation of lipooligosaccharide cores affects immunogenicity and serum resistance of Campylobacter jejuni. Infect. Immun. 68:6656-6662.
8. Guerry, P., C. M. Szymanski, M. M. Prendergast, T. E. Hickey, C. P. Ewing, D. L. Pattarini, and A. P. Moran. 2002. Phase variation of Campylobacter jejuni 81-176 lipooligosaccharide affects ganglioside mimicry and invasiveness in vitro. Infect. Immun. 70:787-793.
9. Linton, D., M. Gilbert, P. G. Hitchen, A. Dell, H. R. Morris, W. W. Wakarchuk, N. A. Gregson, and B. W. Wren. 2000. Phase variation of a β-1,3-galactosyltransferase involved in generation of the ganglioside GM1-like lipo-oligosaccharide of Campylobacter jejuni. Mol. Microbiol. 37:501-514.
10. Linton, D., A. V. Karlyshev, P. G. Hitchen, H. R. Morris, A. Dell, N. A. Gregson, and B. W. Wren. 2000. Multiple N-acetyl neuraminic acid synthetase (neuB) genes in Campylobacter jejuni: identification and characterization of the gene involved in sialylation of lipo-oligosaccharide. Mol. Microbiol. 35:1120-1134.
11. Nachamkin, I., B. M. Allos, and T. Ho. 1998. Campylobacter species and Guillain-Barre syndrome. Clin. Microbiol. Rev. 11:555-567.
12. Oldfield, N. J., A. P. Moran, L. A. Mlllar, M. M. Prendergast, and J. M. Ketley. 2002. Characterization of the Campylobacter jejuni heptosyltransferase II gene, waaF, provides genetic evidence that extracellular polysaccharide is lipid A core independent. J. Bacteriol. 184:2100-2107.
13. Palmer, S. R., P. R. Gully, J. M. White, A. D. Pearson, W. G. Suckling, D. M. Jones, J. C. Rawes, and J. L. Penner. 1983. Water-borne outbreak of Campylobacter gastroenteritis. Lancet 1:287-290.
14. Parker, C. T., S. T. Horn, M. Gilbert, W. G. Miller, D. L. Woodward, and R. E. Mandrell. 2005. Comparison of Campylobacter jejuni lipooligosaccharide biosynthesis loci from a variety of sources. J. Clin. Microbiol. 43:2771-2781.
15. Parkhill, J., B. W. Wren, K. Mungall, J. M. Ketley, C. Churcher, D. Basham, T. Chillingworth, R. M. Davies, T. Feltwell, S. Holroyd, K. Jagels, A. V. Karlysbev, S. Moule, M. J. Pallen, C. W. Penn, M. A. Quail, M. A. Rajandream, K. M. Rutherford, A. H. van Vliet, S. Whttehead, and B. G. Barrell. 2000. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 403:665-668.
16. Wassenaar, T. M., B. N. Fry, and B. A. van der Zeijst 1995. Variation of the flagellin gene locus of Campylobacter jejuni by recombination and horizontal gene transfer. Microbiology 141(Pt. 1):95-101.
17. Watanabe, H., K. Shindo, Y. Nakamura, M. Nagamatsu, Z. Shiozawa, and S. Kusunoki. 2001. A case of Guillain-Barre syndrome after Campylobacter jejuni enterocolitis: anti-ganglioside antibody levels with or without Guillain-Barre syndrome. Rinsho Shinkeigaku 41:625-627.
18. Yuki, N., K. Susuki, M. Koga, Y. Nishimoto, M. Odaka, K. Hirata, K. Taguchi, T. Miyatake, K. Furukawa, T. Kobata, and M. Yamada. 2004. Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome. Proc. Natl. Acad. Sci. USA 101:11404-11409.