A high-salt diet dissociates NO synthase-3 expression and NO production by the thick ascending limb

Hypertension

Volumn 47, Issue 1, 2006, Pages 95-101

  Herrera, Marcela ^a   Silva, Guillermo ^a   Garvin, Jeffrey L ^a,b,c  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HENRY FORD HOSPITAL   (United States)

Author keywords

Kidney; Nitric oxide synthase; Phosphorylation

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERINE; SODIUM CHLORIDE; SUPEROXIDE; TETRAHYDROBIOPTERIN; THREONINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HENLE LOOP; HIGH SODIUM INTAKE; HYPOTHESIS; INHIBITION KINETICS; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; SODIUM TRANSPORT;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; LOOP OF HENLE; MALE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE, DIETARY; TIME FACTORS;

EID: 31744432843     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000196274.78603.85     Document Type: Article

References (34)

1. Ortiz PA, Hong NJ, Garvin JL. NO decreases thick ascending limb chloride absorption by reducing Na(+)-K(+)-2Cl(-) cotransporter activity. Am J Physiol Renal Physiol. 2001;281:F819-F825.
2. Herrera M, Garvin JL. A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1. Am J Physiol Renal Physiol. 2005;288:F58-F64.
3. Herrera M, Garvin JL. Endothelin stimulates endothelial nitric oxide synthase expression in the thick ascending limb. Am J Physiol Renal Physiol. 2004;287:F231-F235.
4. Ortiz P, Stoos BA, Hong NJ, Boesch DM, Plato CF, Garvin JL. High-salt diet increases sensitivity to NO and eNOS expression but not NO production in THALs. Hypertension. 2003;41:682-687.
5. Varela M, Herrera M, Garvin JL. Inhibition of Na/K ATPase in thick ascending limbs by NO depends on O2- and is diminished by high-salt diet. Am J Physiol Renal Physiol. 2004;15:269-275.
6. MacMicking J, Xie QW, Nathan C. Nitric oxide and macrophage function. Annu Rev Immunol. 1997;15:323-350.
7. Herrera M, Garvin JL. Recent advances in the regulation of nitric oxide in the kidney. Hypertension. 2005;45:1062-1067.
8. Fulton D, Gratton JP, Sessa WC. Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther. 2001;299:818-824.
9. Ortiz PA, Hong NJ, Garvin JL. Luminal flow induces eNOS activation and translocation in the rat thick ascending limb. Am J Physiol Renal Physiol. 2004;287:F274-F280.
10. Lee DL, Sasser JM, Hobbs JL, Boriskie A, Pollock DM, Carmines PK, Pollock JS. Posttranslational regulation of NO synthase activity in the renal medulla of diabetic rats. Am J Physiol Renal Physiol. 2005;288: F82-F90.
11. Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA Jr, Sessa WC. Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. J Biol Chem. 2003;278:44719-44726.
12. Gorren AC, Schrammel A, Schmidt K, Mayer B. Effects of pH on the structure and function of neuronal nitric oxide synthase. Biochem J. 1998;331:801-807.
13. Prabhakar SS. Inhibition of mesangial iNOS by reduced extracellular pH is associated with uncoupling of NADPH oxidation. Kidney Int. 2002; 61:2015-2024.
14. Taylor N, Cowley AW Jr. Mechanism of NOS uncoupling in the renal medulla of Dahl S rats. Hypertension. 2004;44:549 (abstract).
15. Plato CF, Shesely EG, Garvin JL. eNOS mediates L-arginine-induced inhibition of thick ascending limb chloride flux. Hypertension. 2000;35: 319-323.
16. Shin SJ, Lai FJ, Wen JD, Lin SR, Hsieh MC, Hsiao PJ, Tsai JH. Increased nitric oxide synthase mRNA expression in the renal medulla of water-deprived rats. Kidney Int. 1999;56:2191-2202.
17. Wang H, Carretero OA, Garvin JL. Nitric oxide produced by THAL nitric oxide synthase inhibits TGF. Hypertension. 2002;39:662-666.
18. Garvey EP, Oplinger JA, Furfine ES, Kiff RJ, Laszlo F, Whittle BJ, Knowles RG. 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo. J Biol Chem. 1997;272:4959-4963.
19. Ni Z, Vaziri ND. Effect of salt loading on nitric oxide synthase expression in normotensive rats. Am J Hypertens. 2001;14:155-163.
20. Sartoretto JL, Melo GA, Carvalho MH, Nigro D, Passaglia RT, Scavone C, Cuman RK, Fortes ZB. Metformin treatment restores the altered microvascular reactivity in neonatal streptozotocin-induced diabetic rats increasing NOS activity, but not NOS expression. Life Sci. In press.
21. Sasser JM, Sullivan JC, Elmarakby AA, Kemp BE, Pollock DM, Pollock JS. Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats. Hypertension. 2004;43:1080-1085.
22. Michell BJ, Chen Z, Tiganis T, Stapleton D, Katsis F, Power DA, Sim AT, Kemp BE. Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase. J Biol Chem. 2001;276:17625-17628.
23. Bauer PM, Fulton D, Boo YC, Sorescu GP, Kemp BE, Jo H, Sessa WC. Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase. J Biol Chem. 2003;278:14841-14849.
24. Fleming I, Fisslthaler B, Dimmeler S, Kemp BE, Busse R. Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. Circ Res. 2001;88:E68-E75.
25. Matsubara M, Titani K, Taniguchi H. Interaction of calmodulin-binding domain peptides of nitric oxide synthase with membrane phospholipids: regulation by protein phosphorylation and Ca(2+)-calmodulin. Biochemistry (Mosc). 1996;35:14651-14658.
26. Aristimuno PC, Good DW. PKC isoforms in rat medullary thick ascending limb: selective activation of the delta-isoform by PGE2. Am J Physiol. 1997;272:F624-F631.
27. Li D, Aperia A, Celsi G, da Cruz e Silva EF, Greengard P, Meister B. Protein phosphatase-1 in the kidney: evidence for a role in the regulation of medullary Na(+)-K(+)-ATPase. Am J Physiol. 1995;269:F673-F680.
28. Gu RM, Wei Y, Falck JR, Krishna UM, Wang WH. Effects of protein tyrosine kinase and protein tyrosine phosphatase on apical K(+) channels in the TAL. Am J Physiol Cell Physiol. 2001;281:C1188-C1195.
29. Fraser S, Mount P, Hill R, Levidiotis V, Katsis F, Stapleton D, Kemp BE, Power DA. Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality. Am J Physiol Renal Physiol. 2005;288:F578-F586.
30. Li D, Wei Y, Wang WH. Dietary K intake regulates the response of apical K channels to adenosine in the thick ascending limb. Am J Physiol Renal Physiol. 2004;287:F954-F959.
31. Buga GM, Griscavage JM, Rogers NE, Ignarro LJ. Negative feedback regulation of endothelial cell function by nitric oxide. Circ Res. 1993;73: 808-812.
32. Sheehy AM, Burson MA, Black SM. Nitric oxide exposure inhibits endothelial NOS activity but not gene expression: a role for superoxide. Am J Physiol. 1998;274:L833-L841.
33. Ortiz PA, Hong NJ, Garvin JL. Luminal flow induces eNOS activation and translocation in the rat thick ascending limb. II. Role of PI3-kinase and Hsp90. Am J Physiol Renal Physiol. 2004;287:F281-F288.
34. Roczniak A, Levine DZ, Burns KD. Localization of protein inhibitor of neuronal nitric oxide synthase in rat kidney. Am J Physiol -Renal Fluid Electrol Physiol. 2000;278:F702-F707.