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Volumn 9, Issue 6, 2005, Pages 626-628

The staging of sepsis: Understanding heterogeneity in treatment efficacy

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DROTRECOGIN; PLACEBO; TUMOR NECROSIS FACTOR ANTIBODY; VASOACTIVE AGENT; PROTEIN C;

EID: 31744431565     PISSN: 13648535     EISSN: None     Source Type: Journal    
DOI: 10.1186/cc3907     Document Type: Note
Times cited : (23)

References (18)
  • 1
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    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • Bone R, Balk R, Cerra F, Dellinger RP, Fein A, Knaus W, Sibbald W: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992, 101: 1644-1655.
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.1    Balk, R.2    Cerra, F.3    Dellinger, R.P.4    Fein, A.5    Knaus, W.6    Sibbald, W.7
  • 4
    • 31744445032 scopus 로고    scopus 로고
    • Lack of evidence for qualitative treatment by disease severity interactions in clinical studies of severe sepsis
    • Macias WL, Nelson DR, Williams M, Garg R, Janes J, Sashegyi A: Lack of evidence for qualitative treatment by disease severity interactions in clinical studies of severe sepsis. Crit Care 2005, 9:R607-R622.
    • (2005) Crit Care , vol.9
    • Macias, W.L.1    Nelson, D.R.2    Williams, M.3    Garg, R.4    Janes, J.5    Sashegyi, A.6
  • 8
    • 0002596502 scopus 로고    scopus 로고
    • Modelling organ dysfunction as a risk factor, outcome, and measure of biologic effect in sepsis: Results of the MONARCS trial
    • Marshall JC, Panacek EA, Teoh L, Barchulk W: Modelling organ dysfunction as a risk factor, outcome, and measure of biologic effect in sepsis: Results of the MONARCS trial. Crit Care Med 2001, 28:A46.
    • (2001) Crit Care Med , vol.28
    • Marshall, J.C.1    Panacek, E.A.2    Teoh, L.3    Barchulk, W.4
  • 9
    • 0343360868 scopus 로고    scopus 로고
    • A multicentre randomized controlled clinical trial of transfusion requirements in critical care
    • the Transfusion Requirements in Critical Care Investigators for the Canadian Critical Care Trials Group
    • Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E, the Transfusion Requirements in Critical Care Investigators for the Canadian Critical Care Trials Group: A multicentre randomized controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999, 340:409-417.
    • (1999) N Engl J Med , vol.340 , pp. 409-417
    • Hebert, P.C.1    Wells, G.2    Blajchman, M.A.3    Marshall, J.4    Martin, C.5    Pagliarello, G.6    Tweeddale, M.7    Schweitzer, I.8    Yetisir, E.9
  • 11
    • 4444273012 scopus 로고    scopus 로고
    • Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: Effect on survival in patients with septic shock
    • Lopez A, Lorente JA, Steingrub J, Bakker J, McLuckie A, Willatts S, Brockway M, Anzueto A, Holzapfel L, Breen D, et al.: Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med 2004, 32:21-30.
    • (2004) Crit Care Med , vol.32 , pp. 21-30
    • Lopez, A.1    Lorente, J.A.2    Steingrub, J.3    Bakker, J.4    McLuckie, A.5    Willatts, S.6    Brockway, M.7    Anzueto, A.8    Holzapfel, L.9    Breen, D.10
  • 12
    • 0038482456 scopus 로고    scopus 로고
    • Such stuff as dreams are made on: Mediator-targeted therapy in sepsis
    • Marshall JC: Such stuff as dreams are made on: Mediator-targeted therapy in sepsis. Nature Rev Drug Disc 2003, 2:391-405.
    • (2003) Nature Rev Drug Disc , vol.2 , pp. 391-405
    • Marshall, J.C.1
  • 13
    • 0023252009 scopus 로고
    • A controlled clinical trial of high dose methylprednisolone in the treatment of severe sepsis and septic shock
    • Bone RC, Fisher CJ, Clemmer TP, Slotman GJ, Metz CA, Balk RA. A controlled clinical trial of high dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med 1987, 317:654-658.
    • (1987) N Engl J Med , vol.317 , pp. 654-658
    • Bone, R.C.1    Fisher, C.J.2    Clemmer, T.P.3    Slotman, G.J.4    Metz, C.A.5    Balk, R.A.6
  • 14
    • 0023239471 scopus 로고
    • Effect of high dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis
    • The Veterans Administration Systemic Sepsis Cooperative Study Group
    • The Veterans Administration Systemic Sepsis Cooperative Study Group: Effect of high dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N Engl J Med 1987, 317:659-665.
    • (1987) N Engl J Med , vol.317 , pp. 659-665


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.