Sensorimotor developmental delays and lower anxiety in rats prenatally exposed to cadmium

Journal of Applied Toxicology

Volumn 26, Issue 1, 2006, Pages 35-41

  Minetti, Alejandra ^a   Reale, Carlos A ^a  

^a UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

Author keywords

Anxiety; Cadmium; Elevated plus maze; Prenatal exposure; Rat; Sensorimotor development

Indexed keywords

CADMIUM;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; AVERSION; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; FEMALE; FETUS; MALE; MAZE TEST; NONHUMAN; ORGANOGENESIS; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; RAT; RIGHTING REFLEX; SENSORIMOTOR FUNCTION;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; CADMIUM; FEAR; FEMALE; MALE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; REFLEX, ABNORMAL;

ANIMALIA;

EID: 31644440858     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1102     Document Type: Article

References (40)

1. Ahokas RA, Dilts PV, Lahaye EB. 1980. Cadmium-induced fetal growth retardation: Protective effect of excess dietary zinc. Am. J. Obstet. Gynecol. 136: 216-221.
2. Ali MM, Murthy RC, Chandra SV. 1986. Developmental and longterm neurobehavioral toxicity of low level in utero cadmium exposure in rats. Neurobehav. Toxicol. Teratol. 8: 463-468.
3. Andersson H, Petersson-Grawe K, Lindqvist E, Luthman J, Oskarsson A, Olson L. 1997. Low-level cadmium exposure of lactating rats causes alterations in brain serotonin levels in the offspring. Neurotoxicol. Teratol. 19: 105-115.
4. Antonio MT, Benito MJ, Leret ML, Corpas I. 1998. Gestational administration of cadmium alters the neurotransmitter levels in newborn rat brains. J. Appl. Toxicol. 18: 83-88.
5. Baranski B. 1987. Effect of cadmium on prenatal development and on tissue cadmium, copper and zinc concentrations in rats. Environ. Res. 42: 54-62.
6. Baranski B, Stetkiewicz I, Sitarek K, Szymczak W. 1983. Effects of oral, subchronic cadmium administration on fertility, prenatal and postnatal progeny development in rats. Arch. Toxicol. 54: 297-302.
7. Chmielewska J, Cherian MG. 1986. Environmental exposure to cadmium and factors affecting trace-element metabolism and metal toxicity. Biol. Trace Elem. Res. 10: 163-175.
8. Chopin P, Briley M. 1987. Animal models of anxiety: the effect of compounds that modify 5-HT neurotransmission. Trends Pharmacol. Sci. 8: 383-388.
9. Choudhuri S, Liu WL, Berman NE, Klaassen CD. 1996. Cadmium accumulation and metallothionein expression in brain of mice at different stages of development. Toxicol. Lett. 84: 127-133.
10. Decker MW, McGaugh JL. 1991. The role of interactions between the cholinergic system and other neuromodulatory systems in learning and memory. Synapse 7: 151-168.
11. Gray JA, Mellanby J, Buckland C. 1984. Behavioural studies of the role of GABA in anxiolytic drug action. Neuropharmacology 23: 827.
12. Gupta A, Gupta A, Murthy RC, Thakur SR, Dubey MP, Chandra SV. 1990. Comparative neurotoxicity of cadmium in growing and adult rats after repeated administration. Biochem. Int. 21: 97-105.
13. Halloway WR, Thor DH. 1988. Cadmium exposure in infancy: Effects on activity and social behavior of juvenile rats. Neurotoxicol. Teratol. 10: 135-142.
14. Hart RP, Rose CS, Hamer RM. 1989. Neuropsychological effects of occupational exposure to cadmium. J. Clin. Exp. Neuropsychol. 11: 933-943.
15. Holt D, Webb M. 1987. Teratogenicity of ionic cadmium in the Wistar rat. Arch. Toxicol. 59: 443-447.
16. Johnson AL, File SE. 1991. Sex differences in animal tests of anxiety. Physiol. Behav. 49: 245-250.
17. Lehotzky K, Ungváry G, Polinák D, Kiss A. 1990. Behavioral deficits due to prenatal exposure to cadmium chloride in CFY rat pups. Neurotoxicol. Teratol. 12: 169-172.
18. Levin AA, Miller RK. 1980. Fetal toxicity of cadmium in the rat: Maternal vs. fetal injections. Teratology 22: 1-6.
19. Machemer L, Lorke D. 1981. Embryotoxic effect of cadmium on rats upon oral administration. Toxicol. Appl. Pharmacol. 58: 438-443.
20. McEntee WJ, Crook TH. 1991. Serotonin, memory, and the aging brain. Psychopharmacology 103: 143-149.
21. Minami A, Takeda A, Nishibaba D, Takefuta S, Oku N. 2001. Cadmium toxicity in synaptic neurotransmission in the brain. Brain Res. 894: 336-339.
22. Muller M, Anke M. 1994. Distribution of cadmium in the food chain (soil-plant-human) of a cadmium exposed area and the health risks of the general population. Sci. Total Environ. 156: 151-158.
23. Newland MC, Ng WW, Baggs RB, Gentry GD, Weiss B, Miller RK. 1986. Operant behavior in transition reflects neonatal exposure to cadmium. Teratology 34: 231-241.
24. O'Callaghan JP, Miller DB. 1986. Diethyldithiocarbamate increases distribution of cadmium to brain but prevents cadmium-induced neurotoxicity. Brain Res. 370: 354-358.
25. Palanza P. 2001. Animal models of anxiety and depression: how are females different? Neurosci. Biobehav. Rev. 25: 219-233.
26. Pellow S, Chopin P, File SE, Briley M. 1985. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods 14: 149-167.
27. Pond WG, Walker EF. 1975. Effect of dietary Ca and Cd level of pregnant rats on reproduction and on dam and progeny mineral concentrations. Proc. Soc. Exp. Biol. Med. 148: 665-668.
28. Rastogi RB, Merali Z, Singhal RL. 1977. Cadmium alters behavior and the biosynthetic capacity for catecholamines and serotonin in neonatal rat brain. J. Neurochem. 28: 789-794.
29. Samarawickrama GP, Webb M. 1979. Acute effects of cadmium on the pregnant rat and embryo-fetal development. Environ. Health Perspect. 28: 245-249.
30. Samarawickrama GP, Webb M. 1981. The acute toxicity and teratogenicity of cadmium in the pregnant rat. J. Appl. Toxicol. 1: 264-269.
31. Smart JL, Dobbing J. 1971. Vulnerability of developing brain. VI. Relative effects of foetal and early postnatal undernutrition on reflex ontogeny and development of behavior in the rat. Brain Res. 33: 303-314.
32. Smith MJ, Pihl RO, Garba B. 1982. Postnatal cadmium exposure and long-term behavioral changes in the rat. Neurobehav. Toxicol. Teratol. 4: 283-287.
33. Sowa B, Steibert E. 1985. Effect of oral cadmium administration to female rats during pregnancy on zinc, copper and iron content in placenta, foetal liver, kidney, intestine and brain. Arch. Toxicol. 56: 256-262.
34. Sutoo D, Akiyama K, Imamiya SA. 1990. A mechanism of cadmium poisoning: the cross effect of calcium and cadmium in the calmodulin-dependent system. Arch. Toxicol. 64: 161-164.
35. Treit D, Robinson A, Rotzinger S, Pesold C. 1993. Anxiolytic effects- of serotonergic interventions in the shock-probe burying test and the elevated plus-maze test. Behav. Brain Res. 54: 23-34.
36. WHO. 1992. Environmental Health Criteria, 134 Cadmium. IPCS: Geneva.
37. Wong KL, Cachia R, Klaassen CD. 1980. Comparison of the toxicity and tissue distribution of cadmium in newborn and adult rats after repeated administration. Toxicol. Appl. Pharmacol. 56: 317-325.
38. Wong KL, Klaassen CD. 1981. Toxic effects of cadmium in the brain of newborn rats. Toxicologist 1: 225.
39. Wong KL, Klaassen CD. 1982. Neurotoxic effects of cadmium in young rats. Toxicol. Appl. Pharmacol. 63: 330-337.
40. Zifa E, Fillion G. 1992. 5-Hydroxytryptamine receptors. Pharmacol. Rev. 44: 401-458.