Independent pathways in the modulation of osteoclastic resorption by intermediates of the mevalonate biosynthetic pathway: The role of the retinoic acid receptor

Bone

Volumn 38, Issue 2, 2006, Pages 167-171

  Van Beek, Ermond ^a   Löwik, Clemens ^a   Karperien, Marcel ^a   Papapoulos, Socrates ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bisphosphonates; Bone resorption; Geranylgeraniol; Mevalonate; Osteoclasts; Retinoic acid receptor

Indexed keywords

4 [2 [5,6 DIHYDRO 5,5 DIMETHYL 8 (4 METHYLPHENYL) 2 NAPHTHYL]ETHYNYL]BENZOIC ACID; GERANYLGERANIOL; GERANYLGERANIOL ACID; GERANYLGERANYL PYROPHOSPHATE; IBANDRONIC ACID; MESSENGER RNA; MEVALONIC ACID; RETINOIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; LONG BONE; MOUSE; NONHUMAN; OSTEOLYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BONE AND BONES; BONE DENSITY CONSERVATION AGENTS; BONE RESORPTION; CALCIUM; DIPHOSPHONATES; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; MEVALONIC ACID; MICE; OSTEOCLASTS; POLYISOPRENYL PHOSPHATES; PREGNANCY; PROTEIN ISOPRENYLATION; RECEPTORS, RETINOIC ACID;

EID: 31544479781     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.08.011     Document Type: Article

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