Protein p62 common in invaginations in benign meningiomas - A possible predictor of malignancy

Clinical Neuropathology

Volumn 25, Issue 1, 2006, Pages 37-43

  Karja V ^a   Alafuzoff, I ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Invaginations; Meningiomas; p62

Indexed keywords

KI 67 ANTIGEN; PROTEIN P62; UBIQUITIN;

ADULT; AGED; ARTICLE; BRAIN CANCER; BREAST CARCINOMA; CANCER DIAGNOSIS; CELL LABELING; CELL NUCLEUS; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; DEGENERATIVE DISEASE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MENINGIOMA; PARAMETER; POSTMENOPAUSE; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UNIVERSITY HOSPITAL;

AGED; BRAIN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MENINGEAL NEOPLASMS; MENINGIOMA; MIDDLE AGED; NEOPLASM INVASIVENESS; POSTMENOPAUSE; RNA-BINDING PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 31544479287     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Beach T, Walker D, Sue L, Newell A, Adler C, Joyce J 2004 Substantia nigra Marinesco bodies are associated with decreased striatal expression of dopamine markers. J Neuropath Experim Neurol 63: 329-337
2. Bertolaet BL, Clarke DJ, Wolff M, Watson MH, Hemze M, Divita G, Reed SI 2001 UBA domains mediate protein-protein interactions between two DNA damage-inducible proteins J Mol Biol 313: 955-963
3. Buchberger A 2002 From UBA to UBX: new words in the ubiquitin vocabulary Trends Cell Biol 12: 216-221
4. Colakoglu N, Demirtas E, Oktar N, Yuntem N, Islekel S, Ozdamar N 2003 Secretory meningiomas. J Neurooncol 62: 233-241
5. Jay V, Edwards V 1996 Filamentous aggregates in a meningioma. Ultrastruct Pathol 20: 577-583
6. Hofmann K, Bucher P 1996 The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway. Trends Biochem Sci 21: 172-173
7. Kalala JP, Caemaert J, De Ridder L 2004 Primary resected meningiomas: relapses and proliferation markers. In vivo 18: 411-416
8. Kawasaki K, Takahashi H, Sato H, Ikuta F 1993 Novel eosinophilic intracytoplasmic inclusions in a meningioma. Cancer 72: 2675-2679
9. Kleihues P, Cavenee WK (eds) 2000 World Health Organisation classification of tumours. Pathology and genetics of tumours of the nervous system. IARC Press, Lyon
10. Kopito RR 2000 Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 10: 524-530
11. Kuusisto E, Salminen A, Alafuzoff I 2001 Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies. Neuroreport 12: 2085-2090
12. Kuusisto E, Suuronen T, Salminen A 2001 Ubiquitin-binding protein p62 expression is induced during apoptosis and proteosomal inhibition in neuronal cells. Biochem Biophys Res Commun 280: 223-228
13. Lusis E, Gutmann DH 2004 Meningioma: an update. Curr Opin Neurol 17: 687-692
14. Matsuno A, Nagashima T, Matsuura R, Tanaka H, Hirakawa M, Murakami M, Tamura A, Kirino T 1996 Correlation between MIB-1 staining index and the immunoreactivity of p53 protein in recurrent and non-recurrent meningiomas. Am J Clin Pathol 106: 776-781
15. Perry A, Scheithauer BW, Stafford SL, Lohse CM, Wollan PC 1999 "Malignancy" in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer 85: 2046-2056
16. Qian HL, Peng XX, chen SH, Ye HM, JH Qui 2005 p62 Expression in primary carcinomas of the digestive system. World J Gastroenterol 11: 1788-1792
17. Shin J 1998 P62 and the sequestosome, a novel mechanism for protein metabolism. Arch Pharm Res 21: 629-633
18. Stumptner C, Heid H, Fuchsbichler A, Hauser H, Mischinger HJ, Zatloukal K, Denk H 1999 Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent. Am J Pathol 154: 1701-1710
19. Stumptner C, Fuchsbichler A, Heidi H, Zatloukal K, Denk H 2002 Mallory body A disease associated type of sequestome. Hepatol 35: 1053-1062
20. Thompson H, Harris J, Wold B, Lin F, Brody J 2003 p62 overexpression in breast tumours and regulation by prostate-derived Ets factor in breast cancer cells. Oncogene 22: 2322-2333
21. Wolfdberger S, Dootskam S, Boecher-Schwarz 2004 Progesterone-receptor index in meningiomas: correlation with clinico-pathological parameters and review of the literature. Neurosurg Rev 27: 238-245
22. Wahab M, Al-Azzawi F 2003 Meningioma and hormonal influences. Climacteric 6: 285-292
23. Wrobel G, Roerig P, Kokocinski F, Neben K, Hahn M, Reifenberger G, Lichter P 2004 Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression. Int J Cancer Nov 11; [Epub ahead of print]
24. Zatloukal K, Stumptner C, Fuchsbichler A, Heid H, Schnoelzer M, Kenner L, Kleinert R, Prinz M, Aguzzi A, Denk H 2002 p62 is a common component of cytoplasmic inclusions in protein aggregation diseases. Am J Pathol 160: 255-263