Pharmacokinetics of a controlled-release misoprostol vaginal insert at term

Journal of the Society for Gynecologic Investigation

Volumn 13, Issue 2, 2006, Pages 112-117

  Rayburn, William F ^b   Powers, Barbara L ^a   Plasse, Terry F ^b   Carr, Denis ^b   Di Spirito, Mike ^b  

^a Cytokine PharmaSciences Inc   (United States)

^b NONE

Author keywords

Cervical ripening; Controlled release; Labor induction; Misoprostol

Indexed keywords

MISOPROSTOL;

AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG RELEASE; FEMALE; HUMAN; HUMAN EXPERIMENT; LABOR INDUCTION; PRIORITY JOURNAL; UTERINE CERVIX RIPENING;

ADMINISTRATION, INTRAVAGINAL; CESAREAN SECTION; DELAYED-ACTION PREPARATIONS; FEMALE; HUMANS; LABOR, INDUCED; MISOPROSTOL; OXYTOCICS; PREGNANCY; PREGNANCY OUTCOME; TREATMENT OUTCOME;

EID: 31544463575     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsgi.2005.10.004     Document Type: Article

References (18)

1. W. Rayburn, J. Zhang Rising rates of labor induction Obstet Gynecol 100 2002 164 167
2. A.H. MacLennan, M. Katz, R. Creasey The morphologic characteristics of cervical ripening induced by the hormones relaxing and prostaglandin F2 in a rabbit model Am J Obstet Gynecol 152 1985 691 696
3. 59th ed. Physicians' Desk Reference 2005 Thomson PDR Montvale, NJ
4. C.J. Hofmeyr, A.M. Gulmezoglu Vaginal misoprostol for cervical ripening and labour induction in late pregnancy (Cochrane Review) 2003 The Cochrane Library, Issue 1 Oxford, UK Update Software
5. Controlled Therapeutics (Scotland) Ltd. Study MISO-OBS-001: data on file, 2002.
6. D. Wing Labor induction with misoprostol Am J Obstet Gynecol 181 1999 339 345
7. American College of Obstetricians and Gynecologists New U.S. Food and Drug Administration labeling on Cytotec (misoprostol) use and pregnancy. ACOG Committee Opinion 2003 ACOG Washington, DC
8. G. Schoenard, J. Opperman, F.E. Kohn Metabolism and pharmacokinetic studies of misoprostol Dig Dis Sci 30 1985 1265 1285
9. American College of Obstetricians and Gynecologists Fetal heart rate patterns monitoring, interpretation, and management. ACOG Technical Bulletin 1995 ACOG Washington, DC
10. American College of Obstetricians and Gynecologists Dystocia and augmentation of labor. ACOG Practice Bulletin 2003 ACOG Washington, DC
11. M. Zieman, S.K. Fong, N.L. Benowitz, D. Bankster, D. Darney Absorption kinetics of misoprostol with oral or vaginal administration Obstet Gynecol 90 1997 88 92
12. O.S. Tang, H. Schweer, H.W. Seyberth, S.W.H. Lee, P.K. Ho Pharmacokinetics of different routes of administration of misoprostol Hum Reprod 17 2002 332 336
13. Controlled Therapeutics (Scotland) Ltd. Study COP/012: data on file, 2002.
14. C. Casteneda, J. Izquierdo Puente, R. Leon Ochoa, T. Plasse, B. Powers, W. Rayburn Misoprostol dose selection in a controlled-release vaginal insert for induction of labor in nulliparous women Am J Obstet Gynecol 193 2005 1071 1075
15. M.C. Williams, J.C.M. Tsibris, G. Davis, J. Baiano, W.F. O'Brien Dose variation that is associated with approximated one-quarter tablet doses of misoprostol Am J Obstet Gynecol 187 2002 615 619
16. US Food and Drug Administration. Centre for Drug Evaluation and Research. Summary Basis of Approval. NDA application No. 20-411, Cervidil1® 1995.
17. 2 from a vaginal insert (0.8 mm, 10 mg) during induction of labour Br J Obstet Gynaecol 108 2001 169 178
18. 2 for induction of labour at term Br J Obstet Gynaecol 82 1974 39 46