Müller cell expression of glutamate cycle related proteins and anti-apoptotic proteins in early human retinal development

British Journal of Ophthalmology

Volumn 90, Issue 2, 2006, Pages 223-228

  Georges, P ^a   Cornish, E E ^a   Provis, J M ^a,b   Madigan, Michele C ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS PROTEIN ANTIBODY; CELL PROTEIN; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE AMMONIA LIGASE; GLUTAMATE ASPARTATE TRANSPORTER; GLUTAMATE CYCLE RELATED PROTEIN; PROTEIN ANTIBODY; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; EYE PROTEIN; GLUTAMATE TRANSPORTER; PROTEIN BCL 2; PROTEIN BCL X;

ARTICLE; FETUS; FETUS (ANATOMY); FLUORESCENCE MICROSCOPY; FROZEN SECTION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOREACTIVITY; MUELLER CELL; NERVE CELL; NERVE CONDUCTION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RETINA DEVELOPMENT; RETINA FOVEA; SYNAPTOSOME; ADULT; APOPTOSIS; CYTOLOGY; GESTATIONAL AGE; GLIA; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METHODOLOGY; PRENATAL DEVELOPMENT; RETINA;

ADULT; AMINO ACID TRANSPORT SYSTEM X-AG; APOPTOSIS; BCL-X PROTEIN; EYE PROTEINS; GESTATIONAL AGE; GLUTAMATE-AMMONIA LIGASE; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, FLUORESCENCE; NEUROGLIA; PROTO-ONCOGENE PROTEINS C-BCL-2; RETINA; SYNAPTOPHYSIN;

EID: 31544453869     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2005.078014     Document Type: Article

References (47)

1. Rauen T, Kanner BI. Localization of the glutamate transporter GLT-1 in rat and macaque monkey retinae. Neurosci Lett 1994;169:137-40.
2. Rauen T, Rothstein JD, Wassle H. Differential expression of three glutamate transporter subtypes in the rat retina. Cell Tissue Res 1996;286:325-36.
3. Pow DV, Barnett NL. Developmental expression of excitatory amino acid transporter 5: a photoreceptor and bipolar cell glutamate transporter in rat retina. Neurosci Lett 2000;280:21-4.
4. Newman E, Reichenbach A. The Müller cell: a functional element of the retina. Trends Neurosci 1996;19:307-12.
5. Danbolt NC. Glutamate uptake. Prog Neurobiol 2001;65:1-105.
6. Prada FA, Quesada A, Dorado ME, et al. Glutamine synthetase (GS) activity and spatial and temporal patterns of GS expression in the developing chick retina: relationship with synaptogenesis in the outer plexiform layer. Glia 1998;22:221-36.
7. Shaked I, Ben-Dror I, Vardimon L. Glutamine synthetase enhances the clearance of extracellular glutamate by the neural retina. J Neurochem 2002;83:574-80.
8. Provis JM. Patterns of cell death in the ganglion cell layer of the human fetal retina. J Comp Neurol 1987;259:237-46.
9. Provis JM, van Driel D, Billson FAB, et al. Human fetal optic nerve: overproduction and elimination of retinal axons during development. J Comp Neurol 1985;238:92-100.
10. Georges P, Madigan MC, Provis JM. Apoptosis during development of the human retina: relationship to foveal development and retinal synaptogenesis. J Comp Neurol 1999;413:198-208.
11. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 1997;3:614-20.
12. Adams JM, Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 1998;281:1322-6.
13. Merry DE, Korsmeyer SJ. bcl-2 gene family in the nervous system. Ann Rev Neurosci 1997;20:245-67.
14. Provis JM, van Driel D, Billson FAB, et al. Development of the human retina: patterns of cell distribution and redistribution in the ganglion cell layer. J Comp Neurol 1985;233:429-451.
15. Wu KH, Madigan MC, Billson FA, et al. Differential expression of GFAP in early v late AMD: a quantitative analysis. Br J Ophthalmol 2003;87:1159-66.
16. Yuodelis C, Hendrickson A. A qualitative and quantitative analysis of the human fovea during development. Vis Res 1986;26:847-55.
17. Knaus P, Betz H, Rehm H. Expression of synaptophysin during postnatal development of the mouse brain. J Neurochem 1986;47:1302-4.
18. Leclerc N, Beesley PW, Brown I, et al. Synaptophysin expression during synaptogenesis in the rat cerebellar cortex. J Comp Neurol 1989;280:197-212.
19. Derouiche A. Possible role of the Müller cell in uptake and metabolism of glutamate in the mammalian outer retina. Vision Res 1996;36:3875-8.
20. Mizutani MC. Gerhardinger M. Lorenzi. Müller cell changes in human diabetic retinopathy. Diabetes 1998;47:445-9.
21. Kugler P, Beyer A. Expression of glutamate transporters in human and rat retina and rat optic nerve. Histochem Cell Biol 2003;120:199-212.
22. Barnett NL, Pow DV. Antisense knockdown of GLAST, a glial glutamate transporter, compromises retinal function. Invest Ophthalmol Vis Sci 2000;41:585-51.
23. Merry DE, Veis DJ, Hickey WF, et al. bcl-2 protein expression in widespread in the developing nervous system and retained in the adult PNS. Development 1994;120:301-11.
24. Gonzalez-Garcia M, Garcia I, Ding L, et al. bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. Proc Natl Acad Sci USA 1995;92:4304-8.
25. Boise LH, Gonzalez GM, Postema CE, et al. Bcl-2, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993;74:597-608.
26. Joseph RM, Li T. Overexpression of Bcl-2 or Bcl-X1 transgenes and photoreceptor degeneration. Invest Ophthalmol Vis Sci 1996;37:2434-46.
27. Chen ST, Garey LJ, Jen, LS. Bcl-2 proto-oncogene protein immunoreactivity in normally developing and axotomised rat retinas. Neurosci Lett 1994;172:11-14.
28. Novack DV, Korsmeyer SJ. Bcl-2 protein expression during murine development. Am J Path 1994;145:61-73.
29. Levin L A, Schlamp CL, Spieldoch RL, et al. Identification of the bcl-2 family of genes in the rat retina. Invest Ophthalmol Vis Sci 1997;38:2545-53.
30. Abu-El-Asrar AM, Dralands L, Missotten L, et al. Expression of apoptosis markers in the retinas of human subjects with diabetes. Invest Ophthalmol Vis Sci 2004;45:2760-6.
31. Podesta F, Romeo G, Liu WH, et al. Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro. Am J Path 2000;156:1025-32.
32. Hartig W, Grosche J, Distler C, et al. Alterations of Müller (glial) cells in dystrophic retinae of RCS rats. J Neurocytol 1995;24:507-17.
33. Grosche J, Hartig W, Reichenbach A. Expression of glial fibrillary acidic protein (GFAP), glutamine synthetase (GS), and Bcl-2 protooncogene protein by Müller (glial) cells in retinal light damage of rats. Neurosci Lett 1995;185:119-22.
34. Kawasaki A, Otori Y, Barnstable CJ. Müller cell protection of rat retinal ganglion cells from glutamate and nitric oxide neurotoxicity. Invest Ophthalmol Vis Sci 2000;41:3444-50.
35. Zhong LT, Kane DJ, Bredesen DE. BCL-2 blocks glutamate toxicity in neural cell lines. Brain Res Mol Brain Res 1993;19:353-5.
36. Yoles E, Riedmann I, Barouch R, et al. Self-protective mechanism awakened by glutamate in retinal ganglion cells. J Neurotrauma 2001;18:339-49.
37. Hockenbery DM, Oltvai ZN, Yin XM, et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993;75:241-51.
38. Tyurin VA, Tyurina YY, Quinn PJ, et al. Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection. Brain Res Mol Brain Res 1998;60:270-81.
39. Bonfanti L, Strettoi E, Chierzi S, et al. Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2. J Neurosci 1996;16:4186-94.
40. Martinou JC, Dubois-Dauphin M, Staple JK, et al. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 1994;13:1017-30.
41. Chierzi S, Cenni MC, Maffei L, et al. Protection of retinal ganglion cells and preservation of function after optic nerve lesion in bcl-2 transgenic mice. Vis Res 1998;38:1537-43.
42. Isenmann S, Kretz A, Cellerino A. Molecular determinants of retinal ganglion cell development, survival, and regeneration. Prog Ret Eye Res 2003;22:483-543.
43. Akhtar RS, Ness JM, Roth KA. Bcl-2 family regulation of neuronal development and neurodegeneration. Biochim Biophys Acta 2004;1644:189-203.
44. Middleton G, Pinon LG, Wyatt S, et al. Bcl-2 accelerates the maturation of early sensory neurons. J Neurosci 1998;18:3344-50.
45. Eom DS, Choi WS, Oh YJ. Bcl-2 enhances neurite extension via activation of c-Jun N-terminal kinase. Biochem Biophys Res Commun 2004;314:377-81.
46. Liang Y, Mimics ZK, Yan C, et al. Bcl-2 mediates induction of neural differentiation. Oncogene 2003;22:5515-18.
47. Cornish EE, Xiao M, Yang Z, et al. The role of opsin expression and apoptosis in determination of cone types in human retina. Exp Eye Res 2004;78:1143-54.