Urothelium cancer with trophoblastic differentiation. An unusual case of a 77 year old patient;Das urothelkarzinom mit trophoblastischer differenzierung. Eine seltene tumorvariante am beispiel einer 77-jährigen patientin

Urologe - Ausgabe A

Volumn 45, Issue 1, 2006, Pages 81-84

  Krah, X ^a   Klose, E ^a   Atanassov, G ^a   Eschholz, G ^a   Kosmehl, H ^b   Weber, H M ^a  

^a HELIOS Klinik Blankenhain   (Germany)

^b HELIOS KLINIKUM ERFURT   (Germany)

Author keywords

Choriocarcinoma; Cystectomy; Gonadotropin; Transitional cell carcinoma; Trophoblastic differentiation

Indexed keywords

BIOLOGICAL MARKER; CHORIONIC GONADOTROPIN BETA SUBUNIT;

AGED; ARTICLE; CANCER INVASION; CANCER SURGERY; CASE REPORT; CELL DIFFERENTIATION; CLINICAL EXAMINATION; CLINICAL FEATURE; HUMAN; PROGNOSIS; STEM CELL; TRANSITIONAL CELL CARCINOMA; TROPHOBLAST; TUMOR VASCULARIZATION; URINARY TRACT CARCINOMA; UROLOGIC SURGERY; UROTHELIUM; UROTHELIUM CARCINOMA;

AGED; CARCINOMA, TRANSITIONAL CELL; CELL DIFFERENTIATION; FEMALE; HUMANS; RARE DISEASES; TREATMENT OUTCOME; TROPHOBLASTIC NEOPLASMS; UROLOGIC NEOPLASMS; UROTHELIUM;

EID: 31544451067     PISSN: 03402592     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00120-005-0953-y     Document Type: Article

References (11)

1. Dexeus F, Logothetis C, Hossan E, Samuels ML (1986) Carcinoembryonic antigen and beta-human chorionic gonadotropin as serum markers for advanced urothelial malignancies. J Urol 136: 403-407
2. Dirnhofer S, Koessler P, Ensinger C et al. (1998) Production of trophoblastic hormones by transitional cell carcinoma of the bladder: association to tumor stage and grade. Hum Pathol 29: 377-382
3. Hindermann W, Berndt A, Haas KM et al. (2003) Immunohistochemical demonstration of the gamma 2 chain of laminin-5 in urinary bladder urothelial carcinoma Impact for diagnosis and prognosis. Cancer Detec Prev 27: 109-115
4. Lazar V, Diez SG, Laurent A et al. (1995) Expression of human chorionic gonadotropin beta subunit genes in superficial and invasive bladder carcinomas. Cancer Res 55: 3735-3738
5. Moldavsky M, Sazbon A, Kuchersky N, Turani H (1997) Urinary bladder transitional cell carcinoma with trophoblastic differentiation. Harefuah 132: 452-454, 528 (Hebrew)
6. McLoughlin J, Pepera T, Bridger J, Williams G (1991) Serum and urinary levels of beta human chorionic gonadotrophin in patients with transitional cell carcinoma. Br J Cancer 63: 822-824
7. Moutzouris G, Yannopoulos D, Barbatis C, Zaharof A, Theodorou C (1993) Is beta-human chorionic gonadotrophin production by transitional cell carcinoma of the bladder a marker of aggressive disease and resistance to radiotherapy? Br J Urol 72: 907-909
8. Regalado JJ (2004) Mixed micropapillary and trophoblastic carcinoma of bladder: report of a first case with new immunohistochemical evidence of urothelial origin. Hum Pathol 35: 382-384
9. Shah VM, Newman J, Crocker J et al. (1987) Production of beta-human chorionic gonadotropin by prostatic adenocarcinoma and transitional cell carcinoma of the upper urinary tract. Br J Exp Pathol 68: 871-878
10. Smith DJ, Evans HJ, Newman J, Chapple CR (1994) Ectopic human chorionic gonadotrophin (HCG) production: Is the detection by serum analysis of HCG of clinical relevance in transitional cell carcinoma of the bladder? Br J Urol 73: 409-412
11. Williams G, Colbeck RA, Crawford SM (1990) Treatment of bladder carcinoma using a germ cell chemotherapy protocol. Br J Urol 65: 473-477