In vivo studies on the effect of Ocimum sanctum L. leaf extract in modifying the genotoxicity induced by chromium and mercury in Allium root meristems

Journal of Environmental Biology

Volumn 27, Issue 1, 2006, Pages 93-95

  Babu, K ^a,c   Maheswari, K C Uma ^b  

^a Cholayil Pharmaceuticals Pvt Ltd   (India)

^b Department of Plant Biology   (India)

^c NONE   (India)

Author keywords

Allium cepa; Chromium; Genotoxicity; Mercury; Ocimum sanctum

Indexed keywords

CHROMIUM; MERCURY; OCIMUM SANCTUM EXTRACT; PLANT EXTRACT;

CHROMIUM; GENOTOXICITY; MERCURY (ELEMENT); PLANT EXTRACT; ROOT SYSTEM;

ARTICLE; CHROMOSOME ABERRATION; CYTOGENETICS; GARLIC; GENOTOXICITY; MERISTEM; MITOSIS INDEX; MUTAGENICITY; NONHUMAN; PLANT ROOT; POLLUTION; SAMPLING; WASTE DISPOSAL;

ALLIUM; ALLIUM CEPA; ALLIUM SATIVUM; OCIMUM TENUIFLORUM;

EID: 31544444955     PISSN: 02548704     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Annapurani, S. and R. Priya: Antimutagenic, antitumourogenic and antigenotoxic effects of polyphenol extracts of selected medicinal plants. The Ind. J. Nutr. Dietet., 36, 431-435 (1999).
2. Aruna, K. and V.M. Sivaramakrishnan: Plant products as protective agents against cancer. Indian J. Exp. Biol., 28, 1008-1011 (1990).
3. Edenharder, R., H. Krieg, V. Kottgen and K.L. Platt: Inhibition of clastogenicity of benzo[a]pyrene and of its trans - 7,8 - dihydrodiol in mice in vivo by fruits, vegetables and flavonoids. Mut. Res., 537, 169-181 (2003).
4. th ed H. Siegel Marcel Dekker Inc. New York (1980).
5. Gupta, S.K., Jai Prakash and Sushma Srivastava: Validation of traditional claim of Tulsi, Ocimum sanctum L. as a medicinal plant. Indian J. Exp. Biol., 40, 765-773 (2002).
6. Kada, T., K. Morita and T. Inoue: Antimutagenic action of vegetable factor(s) on the mutagenic principle of tryptophan pyrolysate. Mut. Res., 53, 351-353 (1978).
7. Kumar, G. and Avinash Tripathi: Comparative mitotoxicity and mutagenicity of two heavy metals in Allium cepa L. J. Cytol. Genet., 4 (NS), 169-173 (2003).
8. Lai, C.N., M.A. Butler and T.S. Matney: Antimutagenic activities of common vegetables and their chlorophyll content. Mut. Res., 77, 245-250 (1980).
9. Majone, F.: Effect of potassium dichromate, on mitosis of cultured cells. Caryologia, 30 (40), 469-481 (1977).
10. Marimuthu, K. M. and M. K. Subramaniam: A haematoxylin squash method for the root tips of Dolichos lablab L. Curr. Sci., 29, 482-483 (1960).
11. Morita, K., H. Masako and T. Kada: Studies on the natural desmutagens: Screening for vegetables and fruit factor(s) on the mutagenic principle of tryptophan pyrolysate. Agr. Biol. Chem., 42, 1235-1238 (1978).
12. Nagao, M.: Environmental mutagens and carcinogens. Ann. Rev. Genet., 12, 117-159 (1978).
13. Salma Khanam, Kshama Devi and H.N. Shivaprasad: Natural antimutagens. Indian. J. Nat. Prod., 20 (2), 3-7 (2004).
14. Sharma, G.P., R.C. Sobti, A. Chaudhry and K.K. Ahluwalia: Genotoxicity of two heavy metal compounds lead acetate and mercuric chloride in the mosquito Anopheles stephensi Liston (Culicidae-Diptera). Cytologia, 53, 263-267 (1988).
15. Tsuda, H and K. Kato: Chromosomal aberrations and morphological transformation in Hamster embryonic cells treated with potassium dichromate in vivo. Mut. Res., 4, 87-94 (1979).
16. Umadevi, P.: Radioprotective, anticarcinogenic and antioxidant properties of the Indian holy basil, Ocimum sanctum (Tulsi). Indian J. Exp. Biol., 39, 185 (2001).
17. Umadevi, P. and A. Ganasoundari: Radioprotective effect of leaf extract of Indian medicinal plant Ocimum sanctum. Indian J. Exp. Biol., 33, 205-208 (1995).
18. Venitt, S and L.S. Levy: Mutagenicity of chromates in bacteria and its relevance to chromate carcinogenesis. Nature, 250, 493-495 (1974).