Colonic fermentation of inulin increases whole-body acetate turnover in dogs

Journal of Nutrition

Volumn 135, Issue 12, 2005, Pages 2845-2851

  Pouteau, E ^a   Frenais, R ^a   Dumon, H ^a   Noah, L ^a   Martin, L ^a   Nguyen, P ^a  

^a LUNAM UNIVERSITÉ   (France)

Author keywords

Acetate; Colonic fermentation; Dogs; Stable isotope

Indexed keywords

ACETIC ACID; INULIN; STABLE ISOTOPE;

ANIMAL EXPERIMENT; ARTICLE; COLON MOTILITY; CONTROLLED STUDY; DIETARY FIBER; DIETARY INTAKE; DOG; FEMALE; FERMENTATION; FOOD INTAKE; INTESTINE FLORA; ISOTOPE LABELING; MALE; NONHUMAN; NUTRIENT CONCENTRATION; NUTRIENT CONTENT; NUTRITIONAL ASSESSMENT; PERIPHERAL CIRCULATION; SPECIES COMPARISON;

ANIMALIA; CANIS FAMILIARIS; CICHORIUM INTYBUS;

EID: 31544440392     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/135.12.2845     Document Type: Article

References (35)

1. Zentek, J. (1996) Cellulose, pectins and guar gum as fibre sources in canine diets. J. Anim. Physiol. Anim. Nutr. 75: 36-45.
2. Spears, J. K. & Fahey, G. C., Jr. (2004) Resistant starch as related to companion animal nutrition. J. Assoc. Off. Anal. Chem. Int. 87: 787-791.
3. Von Engelhardt, W., Ronnau, K., Rechkemmer, G. & Sakata, T. (1989) Absorption of short-chain fatty acids and their role in the hindgut of monogastric animals. Anim. Feed Sci. Technol. 23: 43-53.
4. McIntyre, A., Gibson, P. R. & Young, G. P. (1993) Butyrate production from dietary fibre and protection against large bowel cancer in a rat model. Gut 34: 386-391.
5. Anderson, J. W. (1995) Short chain fatty acids and lipid metabolism: human studies. In: Physiological and Clinical Aspects of Short-Chain Fatty Acids (Cummings, J. H., Rombeau, J. L. & Sakata, T., eds.), pp. 509-523. Cambridge University Press, New York, NY.
6. Illman, R. J., Topping, D. L., McIntosh, G. H., Trimble, R. P., Storer, G. B., Taylor, M. N. & Cheng, B. Q. (1988) Hypocholesterolaemic effects of dietary propionate: studies in whole animals and perfused rat liver. Ann. Nutr. Metab. 32: 95-107.
7. Bleiberg, B., Beers, T. R., Person, M. & Miles, J. M. (1992) Systemic and regional acetate kinetics in dogs. Am. J. Physiol. 262: E197-E202.
8. Pouteau, E., Dumon, H., Nguyen, P., Darmaun, D., Champ, M. & Krempf, M. (1998) Whole-body, peripheral and intestinal endogenous acetate turnover in dogs using stable isotopes. J. Nutr. 128: 111-115.
9. Veldman, F. J., Nair, C. H., Voster, H. H., Vermaak, W.J.H., Jerling, J. C., Oosthuizen, W. & Venter, C. S. (1999) Possible mechanisms through which dietary pectin influences fibrin network architecture in hypercholesterolaemic subjects. Thromb. Res. 93: 253-264.
10. Puchowicz, M., Bederman, I., Comte, B., Yang, D., David, F., Stone, E., Jabbour, K., Wasserman, D. & Brunengraber, H. (1999) Zonation of acetate labeling across the liver: implications for studies of lipogenesis by MIDA. Am. J. Physiol. 277: E1022-E1027.
11. Knowles, S. E., Jarret, I. G., Filsell, O. H. & Ballard, F. J. (1974) Production and utilization of acetate in mammals. Biochem. J. 142: 401-411.
12. Pouteau, E., Vahedi, K., Messing, B., Flourie, B., Nguyen, P., Darmaun, D. & Krempf, M. (1998) Production rate of acetate during colonic fermentation of lactulose: a stable-isotope study in humans. Am. J. Clin. Nutr. 68: 1276-1283.
13. Pouteau, E., Dumon, H., Biourge, V., Krempf, M. & Nguyen, P. (1998) Lactulose ingestion has no effect on plasma acetate in dogs studied with [1-13C] acetate. J. Nutr. 128: 2663S-2665S.
14. Rastall, R. A. (2004) Bacteria in the gut: friends and foes and how to alter the balance. J. Nutr. 134: 2022S-2026S.
15. Pouteau, E., Dumon, H., Biourge, V., Krempf, M. & Nguyen, P. (1998) Hydrogen production in dogs adapts to addition of lactulose and to a meat and rice diet. J. Nutr. 128: 2666S-2668S.
16. Flickinger, E. A., Schreijen, E.M.W.C., Patil, E. R., Hussein, H. S., Grieshop, C. M., Merchen, N. R. & Fahey, G. C., Jr. (2003) Nutrient digestibilities, microbial populations, and protein catabolites as affected by fructan supplementation of dog diets. J. Anim. Sci. 81: 2008-2018.
17. Simoneau, C., Pouteau, E., Maugeais, P., Marks, L., Ranganathan, S., Champ, M. & Krempf, M. (1994) Measurement of whole body acetate turnover in healthy subjects with stable isotopes. Biol. Mass Spectrom. 23: 430-433.
18. Pouteau, E., Meirim, I., Metairon, S. & Fay, L. B. (2001) Acetate, propionate and butyrate in plasma: determination of the concentration and isotopic enrichment by gas chromatography/mass spectrometry with positive chemical ionization. J. Mass Spectrom. 36: 798-805.
19. Rosenblatt, J., Chinkes, D., Wolfe, M. & Wolfe, R. (1992) Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects. Am. J. Physiol. 263: E584-E596.
20. Diez, M. & Istasse, L. (1996) Dietary fibres in dogs: I. Definition and chemical composition. Ann. Med. Vet. 140: 385-391.
21. Norwich, K. H. (1992) Sites of infusion and sampling for measurement of rates production in steady state. Am. J. Physiol. 263: E817-E822.
22. 13C] acetate. Am. J. Physiol. 271: E58-E64.
23. 13C-enriched starchy food in normal humans. Am. J. Clin. Nutr. 55: 430-435.
24. 2 during the infusion of C-1- vs C-2-labeled acetate: implications for tracer studies of substrate oxidation. Am. J. Clin. Nutr. 51: 248-252.
25. Wolfe, R. R. (1992) Measurement of substrate oxidation. In: Radioactive and Stable Isotope Tracers in Biomedicine: Principle and Practice of Kinetic Analysis (Wolfe, R. R., ed.), pp. 235-282. Wiley-Liss, New York, NY.
26. Chioléro, R., Mavrocordatos, P., Burnier, P., Cayeux, M. C., Schindler, C., Jéquier, E. & Tappy, L. (1993) Effects of infused sodium acetate, sodium lactate, and β-hydroxybutyrate on energy expenditure and substrate oxidation rates in lean humans. Am. J. Clin. Nutr. 53: 608-613.
27. Weir, J. B. (1949) New methods for calculating metabolic rate with special reference to protein metabolism. J. Physiol. 109: 1-9.
28. Annison, E. F. & White, R. R. (1962) Further studies of the entry rates of acetate and glucose in sheep with special reference to endogenous production of acetate. Biochem. J. 84: 546-552.
29. Roberfroid, M., Gibson, G. R. & Delzenne, N. (1993) The biochemistry of oligofructose, a nondigestible fiber: an approach to calculate its caloric value. Nutr. Rev. 51: 137-146.
30. Propst, E. L., Flickinger, E. A., Bauer, L. L., Merchen, N. R. & Fahey G. C., Jr. (2003) A dose-response experiment evaluating the effects of oligofructose and inulin on nutrient digestibility, stool quality, and fecal protein catabolites in healthy adult dogs. J. Anim. Sci. 81: 3057-3066.
31. Snoswell, A. M., Trimble, R. P., Fishlock, R. C., Storer, G. B., Topping, D. L. (1982) Metabolic effects of acetate in perfused rat liver. Studies on ketogenesis, glucose output, lactate uptake and lipogenesis. Biochim. Biophys. Acta 716: 290-297.
32. Buckley, B. M. & Williamson, D. H. (1977) Origins of blood acetate in the rat. Biochem. J. 166: 539-545.
33. Skutches, C. L., Holroyde, C. P., Myers, R. N., Paul, P. & Reichard, G. A. (1979) Plasma acetate turnover and oxidation. J. Clin. Investig. 64: 708-13.
34. Rémésy, C., Demigné, C. & Morand, C. (1995) Metabolism of short chain fatty acids in the liver. In: Physiological and Clinical Aspects of Short-Chain Fatty Acids (Cummings, J. H., Rombeau, J. L. & Sakata, T., eds.), pp. 117-190. Cambridge University Press, New York, NY.
35. Zhang, Y., Agarwal, K. C., Beylot, M., Soloviev, M. V., David, F., Reider, M. W., Anderson, V. E., Tserng, K. & Brunengraber, H. (1994) Nonhomogeneous labeling of liver extra-mitochondrial acetyl-CoA. Implications for the probing of lipogenic acetyl-CoA via drug acetylation and for the production of acetate by the liver. J. Biol. Chem. 269: 11025-11029.