Improved assay for R(-)-apomorphine with application to clinical pharmacokinetic studies in Parkinson's disease

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 831, Issue 1-2, 2006, Pages 1-7

  Ingram, Wendy M ^a,b   Priston, Melanie J ^a,b   Sewell, Graham J ^a,c  

^a DERRIFORD HOSPITAL   (United Kingdom)

^b UNIVERSITY OF PLYMOUTH   (United Kingdom)

^c KINGSTON UNIVERSITY   (United Kingdom)

Author keywords

Apomorphine; HPLC; Parkinson's disease; Pharmacokinetics; Plasma; Solid phase extraction

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DISEASE CONTROL; FLUORESCENCE; METABOLITES; OPTIMIZATION; PLASMAS;

APOMORPHINE; HPLC; PARKINSON'S DISEASE; PHARMACOKINETIC STUDIES; SOLID PHASE EXTRACTION;

PHARMACOKINETICS;

ANTIPARKINSON AGENT; APOMORPHINE; ASCORBIC ACID;

ARTICLE; BLOOD SAMPLING; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; FLUORESCENCE; FREEZE THAWING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; VALIDATION PROCESS;

APOMORPHINE; ASCORBIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FREEZING; HUMANS; PARKINSON DISEASE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

PARKINSONIA;

EID: 31544438857     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.11.005     Document Type: Article

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