Bone disorders in experimentally induced liver disease in growing rats

World Journal of Gastroenterology

Volumn 11, Issue 45, 2005, Pages 7169-7173

  Ferencz, Viktória ^a   Horváth, Csaba ^a   Kári, Béla ^a   Gaál, János ^b   Mészáros, Szilvia ^a   Wolf, Zsuzsanna ^a   Hegedus, Dalma ^a   Horváth, Andrea ^a   Folhoffer, Anikó ^a   Szalay, Ferenc ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

Author keywords

Bone disorder; Bone mineral content; Experimental liver cirrhosis; Growing rat; Mechanical resistance

Indexed keywords

CARBON TETRACHLORIDE; DIETHYLNITROSAMINE; PHENOBARBITAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DISEASE; BONE GROWTH; BONE MASS; BONE MINERAL; BONE STRENGTH; CONTROLLED STUDY; CORTICAL BONE; EXPERIMENTAL RAT; FATTY LIVER; FEMUR; GROWTH INHIBITION; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER DISEASE; LOADING TEST; MALE; NONHUMAN; RAT; RAT STRAIN; THICKNESS;

EID: 31544433694     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i45.7169     Document Type: Article

References (33)

1. Diamond T, Stiel D, Lunzer M, Wilkinson M, Roche J, Posen S. Osteoporosis and skeletal fractures in chronic liver disease. Gut 1990; 31: 82-87
2. Heathcote J. Osteoporosis in chronic liver disease. Curr Gastroenterol Rep 1999; 1: 455-458
3. McCaughan GW, Feller RB. Osteoporosis in chronic liver disease: pathogenesis, risk factors, and management. Dig Dis 1994; 12: 223-231
4. Monegal A, Navasa M, Guanabens N, Peris P, Pons F, Martinez de Osaba MJ, Rimola A, Rodes J, Munoz-Gomez J. Osteoporosis and bone mineral metabolism disorders in cirrhotic patients referred for orthotopic liver transplantation. Calcif Tissue Int 1997; 60: 148-154
5. Corazza GR, Trevisani F, Di Stefano M, De Notariis S, Veneto G, Cecchetti L, Minguzzi L, Gasbarrini G, Bernardi M. Early increase of bone resorption in patients with liver cirrhosis secondary to viral hepatitis. Dig Dis Sci 2000; 45: 1392-1399
6. Moller S, Hansen M, Hillingso J, Jensen JE, Henriksen JH. Elevated carboxy terminal cross linked telopeptide of type I collagen in alcoholic cirrhosis: relation to liver and kidney function and bone metabolism. Gut 1999; 44: 417-423
7. Chappard D, Plantard B, Fraisse H, Palle S, Alexandre C, Riffat G. Bone changes in alcoholic cirrhosis of the liver. A histomorphometry study. Pathol Res Pract 1989; 184: 480-485
8. Diamond TH, Stiel D, Lunzer M, McDowall D, Eckstein RP, Posen S. Hepatic osteodystrophy. Static and dynamic bone histomorphometry and serum bone Gla-protein in 80 patients with chronic liver disease. Gastroenterology 1989; 96: 213-221
9. Capra F, Casaril M, Gabrielli GB, Stanzial A, Ferrari S, Gandini G, Falezza G, Corrocher R. Plasma osteocalcin levels in liver cirrhosis. Ital J Gastroenterol 1991; 23: 124-127
10. Pietschmann P, Resch H, Muller C, Woloszczuk W, Willvonseder R. Decreased serum osteocalcin levels in patients with liver cirrhosis. Bone Miner 1990; 8: 103-108
11. Tsuneoka K, Tameda Y, Takase K, Nakano T. Osteodystrophy in patients with chronic hepatitis and liver cirrhosis. J Gastroenterol 1996; 31: 669-678
12. Kalef-Ezra JA, Merkouropoulos MH, Challa A, Hatzikonstantinou J, Karantanas AH, Tsianos EV. Amount and composition of bone minerals in chronic liver disease. Dig Dis Sci 1996; 41: 1008-1013
13. Stellon AJ, Davies A, Compston J, Williams R. Osteoporosis in chronic cholestatic liver disease. Q J Med 1985; 57: 783-790
14. Zalatnai A, Lapis K. Simultaneous induction of liver cirrhosis and hepatocellular carcinomas in F-344 rats: establishment of a short hepatocarcinogenesis model. Exp Toxic Pathol 1994; 46: 215-222
15. Pilette C, Rousselet MC, Bedossa P, Chappard D, Oberti F, Rifflet H, Maiga MY, Gallois Y, Cales P. Histopathological evaluation of liver fibrosis: quantitative image analysis vs Semi-quantitative scores. Comparison with serum markers. J Hepatol 1998; 28: 439-446
16. Stewart HL, williams G, Keysser CH, Lombard LS,Montaly RJ. Histologic typing of liver tumors of the rat. Institute of Laboratory Animal Resources, National Research Council, National Academy of Sciences, Washington, D.C. J Natl Cancer Inst 1980; 64: 177-206
17. Mosekilde L, Thomsen JS, Orhii PB, McCarter RJ, Mejia W, Kalu DN. Additive effect of voluntary exercise and growth hormone treatment on bone strength assessed at four different skeletal sites in an aged rat model. Bone 1999; 24: 71-80
18. Cemborain A, Castilla-Cortazar I, Garcia M, Quiroga J, Muguerza B, Picardi A, Santidrian S, Prieto J. Osteopenia in rats with liver cirrhosis: beneficial effects of IGF-I treatment. J Hepatol 1998; 28: 122-131
19. Nakano A, Kanda T, Abe H. Bone changes and mineral metabolism disorders in rats with experimental liver cirrhosis. J Gastroenterol Hepatol 1996; 11: 1143-1154
20. Cemborain A, Castilla-Cortazar I, Garcia M, Muguerza B, Delgado G, Diaz-Sanchez M, Picardi A. Effects of IGF-I treatment on osteopenia in rats with advanced liver cirrhosis. J Physiol Biochem 2000; 56: 91-99
21. Mabuchi M, Kawamura I, Fushimi M, Inoue T, Takeshita S, Takakura S, Matsuo M, Tomoi M, Goto T. Induction of bone loss by bile duct ligation in rats. In Vivo 2001; 15: 281-287
22. van der Merwe SW, van den Bogaerde JB, Goosen C, Maree FF, Milner RJ, Schnitzler CM, Biscardi A, Mesquita JM, Engelbrecht G, Kahn D, Fevery J. Hepatic osteodystrophy in rats results mainly from portasystemic shunting. Gut 2003; 52: 580-585
23. Muguerza B, Lecaroz C, Picardi A, Castilla-Cortazar I, Quiroga J, Cemborain A, Prieto J, Santidrian S. A potential experimental model for the study of osteopenia in CCl4 liver cirrhotic rats. Rev Esp Fisiol 1996; 52: 113-119
24. Tanaka S, Tsurukami H, Sakai A, Okimoto N, Ikeda S, Otomo H, Nakamura T. Effects of 1,25(OH)2D3 on turnover, mineralization, and strength of bone in growing rats with liver cirrhosis induced by administration of carbon tetrachloride. Bone 2003; 32: 275-283
25. Bauer D, Wolfram N, Kahl GF, Hirsch-Ernst KI. Transcriptional regulation of CYP2B1 induction in primary rat hepatocyte cultures: repression by epidermal growth factor is mediated via a distal enhancer region. Mol Pharmacol 2004; 65: 172-180
26. Nebert DW, Russell DW. Clinical importance of the cytochromes P450. Lancet 2002; 360: 1155-1162
27. Wikvall K. Cytochrome P450 enzymes in the bioactivation of vitamin D to its hormonal form (review). Int J Mol Med 2001; 7: 201-209
28. Wyde ME, Bartolucci E, Ueda A, Zhang H, Yan B, Negishi M, You L. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor. Mol Pharmacol 2003; 64: 474-481
29. Figueiredo FA, Brandao C, Perez Rde M, Barbosa WF, Kondo M. Low bone mineral density in noncholestatic liver cirrhosis: prevalence, severity and prediction. Arq Gastroenterol 2003; 40: 152-158
30. Janes CH, Dickson ER, Okazaki R, Bonde S, McDonagh AF, Riggs BL. Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice. J Clin Invest 1995; 95: 2581-2586
31. Volkman SK, Galecki AT, Burke DT, Paczas MR, Moalli MR, Miller RA, Goldstein SA. Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J Bone Miner Res 2003; 18: 1497-1505
32. Stenstrom M, Olander B, Lehto-Axtelius D, Madsen JE, Nordsletten L, Carlsson GA. Bone mineral density and bone structure parameters as predictors of bone strength: an analysis using computerized microtomography and gastrectomy-induced osteopenia in the rat. J Biomech 2000; 33: 289-297
33. Nordsletten L, Kaastad TS, Madsen JE, Reikeras O, Ovstebo R, Stromme JH, Falch J. The development of femoral osteopenia in ovariectomized rats is not reduced by high intensity treadmill training: a mechanical and densitometric study. Calcif Tissue Int 1994; 55: 436-442