The role of 18F-fluorodeoxyglucose positron emission tomography in gestational trophoblastic tumours: A pilot study

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 33, Issue 2, 2006, Pages 156-163

  Ting, Chang Chang ^a   Tzu, Chen Yen ^b   Yiu, Tai Li ^c   Yen, Ching Wu ^a   Yu, Cheng Chang ^b   Koon, Kwan Ng ^b   Shih, Ming Jung ^a   Tzu, I Wu ^a   Chyong, Huey Lai ^a,d  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c KUO GENERAL HOSPITAL   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

hCG; 18F FDG; Chemoresistant; Gestational trophoblastic tumour; PET

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; FLUORODEOXYGLUCOSE F 18; ANTINEOPLASTIC AGENT; DIAGNOSTIC AGENT;

ADULT; ARTICLE; BIOLOGICAL MONITORING; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONFORMATION; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DIAGNOSTIC PROCEDURE; FOLLOW UP; HUMAN; METASTASIS; ONSET AGE; PILOT STUDY; POSITRON EMISSION TOMOGRAPHY; PREGNANCY; RECURRENT DISEASE; TROPHOBLASTIC TUMOR; WORLD HEALTH ORGANIZATION; BLOOD; FEMALE; IMAGE PROCESSING; METHODOLOGY; MIDDLE AGED; PATHOLOGY;

ADULT; ANTINEOPLASTIC AGENTS; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; FEMALE; FLUORODEOXYGLUCOSE F18; GESTATIONAL TROPHOBLASTIC NEOPLASMS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MIDDLE AGED; NEOPLASM METASTASIS; PILOT PROJECTS; POSITRON-EMISSION TOMOGRAPHY; PREGNANCY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 31444456438     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-005-1873-1     Document Type: Article

References (25)

1. Bower M, Newlands ES, Holden L, Short D, Rustin GJ, Begent RH, et al. EMA/CO for high-risk gestational trophoblastic tumours: results from a cohort of 272 patients. J Clin Oncol 1997;15:2636-43
2. Lehman E, Gershenson DM, Burke TW, Levenback C, Silva EG, Morris M. Salvage surgery for chemorefractory gestational trophoblastic disease. J Clin Oncol 1994;12:2737-42
3. Newlands ES, Bower M, Holden L, Short D, Seckl MJ, Rustin GJ, et al. Management of resistant gestational trophoblastic tumours. J Reprod Med 1998;43:111-8
4. Feltmate CM, Genest DR, Wise L, Berstein MR, Goldstein DP, Berkowitz RS. Placental site trophoblastic tumour: a 17-year experience at the New England Trophoblastic Disease Center. Gynecol Oncol 2001;82:415-9
5. Hricak H, Demas BE, Braga CA, Fisher MR, Winkler ML. Gestational trophoblastic neoplasm of the uterus: MR assessment. Radiology 1986;161:11-6
6. Hillard AE, Allen RW, Beale G. Metastatic choriocarcinoma: correlation of MRI, CT, and angiography. South Med J 1993;86: 1299-302
7. Gambhir SS, Czenin J, Schwimmer J, Silverman DHS, Coleman RE, Phelps MW. A tabulated summary of the FDG PET literature. J Nucl Med 2001;42:1S-93S
8. Yen TC, Ng KK, Ma SY, Chou HH, Tsai CS, Hsueh S, et al. Value of dual-phase 2-fluoro-2-deoxy-D-glucose positron emission tomography in cervical cancer. J Clin Oncol 2003;21:3651-8
9. Chang TC, Law KS, Hong JH, Lai CH, Yen TC, Ng KK, et al. Positron emission tomography for unexplained serum SCC-Ag elevation in cervical cancer patients - a phase II study. Cancer 2004;101:164-71
10. Hebart H, Erley C, Kaskas B, Mayer R, Konig M, Einsele H, et al. Positron emission tomography helps to diagnose tumour emboli and residual disease in choriocarcinoma. Ann Oncol 1996;7:416-8
11. Truenbach J, Pereira PL, Huppert PE, Farnsworth C, Mayer R, Feline U, et al. Primary choriocarcinoma of the pulmonary artery mimicking pulmonary embolism. Br J Radiol 1997;70:843-5
12. Zhuang H, Yamamoto AJ, Ghesani N, Alavi A. Detection of choriocarcinoma in the lung by FDG positron emission tomography. Clin Nucl Med 2001;26:723
13. 18F-FDG-PET. A case report. Clin Positron Imaging 2000;3:37-40
14. 18F]fluorodeoxyglucose positron emission tomography as a useful indicator of metastatic gestational trophoblastic tumour: preliminary results in three patients. Gynecol Oncol 2003;91:226-30
15. Bagshawe KD. Choriocarcinoma. A model for tumour markers. Acta Oncol 1992;31:99-106
16. World Health Organization. Gestational trophoblastic diseases. WHO Technical Report Series. Switzerland: WHO; 1983. p. 692
17. Mutch DG, Soper JT, Babcock CJ, Clerke-Pearson DL, Hammond CB. Recurrent gestational trophoblastic disease. Experience of the Southern Regional Trophoblastic Disease Center. Cancer 1990;66:978-82
18. Tsai CC, Tsai CS, Ng KK, Ma SY, Chou HH, Tsai CS, et al. The impact of image fusion in resolving discrepant findings between FDG-PET and MRI/CT in patients with gynaecological cancers. Eur J Nucl Med Mol Imaging 2003;30:1674-83
19. Matsui H, Suzuka K, Litsuka Y, Yamazawa K, Tanaka N, Mitsuhashi A, et al. Salvage combination chemotherapy with 5-fluorouracil and actinomycin D for patients with refractory, high-risk gestational trophoblastic tumours. Cancer 2002;95: 1051-4
20. Chen LP, Cai SM, Fan JX, Li ZT. PEBA regimen (cisplatin, etoposide, bleomycin, and adriamycin) in the treatment of drug-resistant choriocarcinoma. Gynecol Oncol 1995;56:231-4
21. Lotz JP, Andre T, Donsimori R, Firmin C, Bouleuc C, Bonnak H, et al. High dose chemotherapy with ifosfamide, carboplatin, and etoposide combined with autologous bone marrow transplantation for the treatment of poor-prognosis germ cell tumours and metastatic trophoblastic disease in adults. Cancer 1995;75:874-85
22. Rustin GJS, Newlands ES, Begent RHJ, Dent J, Bagshawe KD. Weekly alternating etoposide, methotrexate, and actinomycin/ vincristine and cyclophosphamide chemotherapy for the treatment of CNS metastases of choriocarcinoma. J Clin Oncol 1989;7:900-3
23. Schechter NR, Mychalczak B, Jones W, Spriggs D. Prognosis of patients treated with whole brain radiation therapy for metastatic gestational trophoblastic disease. Gynecol Oncol 1998;68:183-92
24. Ngan HY, Chan FL, Au VWK, Cheng DKL, Ng TY, Wong LC. Clinical outcome of micrometastasis in the lung in stage IA persistent gestational trophoblastic disease. Gynecol Oncol 1998;70:192-4
25. Gillespie AM, Kumar S, Hancock BW Treatment of persistent trophoblastic diease later than 6 months after diagnosis of molar pregnancy. Br J Cancer 2000;82:1393-5