Aminoalkylation of nitriles by iminium ions generated in situ

Tetrahedron Letters

Volumn 47, Issue 9, 2006, Pages 1465-1467

  Katritzky, Alan R ^a   Abdel Fattah, Ashraf A A ^a   Steel, Peter J ^b  

^a University of Florida   (United States)

^b UNIVERSITY OF CANTERBURY   (New Zealand)

Author keywords

Aminoalkyl nitriles; Aminoalkylation; N ( Aminoalkyl)benzotriazoles

Indexed keywords

BENZOTRIAZOLE DERIVATIVE; N (ALPHA AMINOALKYL)BENZOTRIAZOLE; NITRILE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHEMICAL REACTION; CRYSTAL STRUCTURE; DIASTEREOISOMER; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

EID: 31444438365     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.12.059     Document Type: Article

References (13)

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12. 4, and the solvent was removed in vacuo. The resulted oil was chromatographed on a silica-gel column using hexanes/EtOAc 10:1 as eluent to give the pure product 5 and 6 ; the yields are presented in Table 1.
13. 3: C, 81.42; H, 7.62; N, 10.96. Found: C, 81.45; H, 7.52; N, 10.71. (c) Complete crystallographic data for all seven X-ray structures, as CIF files, have been deposited with the Cambridge Crystallographic Data Centre (CCDC Nos. 281472-281478). Copies can be obtained free of charge from: The Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (e-mail: deposit@ccdc.cam.ac.uk ).