Segmental difference of mucosal damage along the length of a mouse small intestine in an Ussing chamber

Journal of Nutritional Science and Vitaminology

Volumn 51, Issue 6, 2005, Pages 406-412

  Inagaki, Eiko ^a   Natori, Yasuo ^a   Ohgishi, Yuki ^b   Hayashi, Hisayoshi ^b   Suzuki, Yuichi ^b  

^a NAGOYA UNIVERSITY OF ARTS AND SCIENCES   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Crypt; Intestinal absorption; Intestinal mucosa; Intestinal secretion; Villous injury

Indexed keywords

FORSKOLIN; GLUCOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVICE; DISEASE MARKER; DUODENUM MUCOSA; HISTOPATHOLOGY; IN VITRO STUDY; INCUBATION TIME; INTESTINE ABSORPTION; INTESTINE EPITHELIUM; INTESTINE INJURY; INTESTINE MUCOSA; INTESTINE SECRETION; INTESTINE VILLUS; JEJUNUM MUCOSA; MALE; MOUSE; NONHUMAN; POTENTIAL DIFFERENCE; SEGMENTAL DIFFERENCE; SEROSA; USSING CHAMBER;

ANIMALIA;

EID: 31444433145     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.51.406     Document Type: Article

References (15)

1. Ussing HH, Zerhan K. 1951. Active transport of sodium as the source of electrical current in the short-circuited isolated frog skin. Acta Physiol Scand 23: 110-127.
2. Hillgren M, Kato A, Borchardt RT. 1994. In vitro systems for studying intestinal drug absorption. Med Res Rev 15: 83-109.
3. Albin DM, Tappenden KA. 2001. Advances in methods to evaluate gastrointestinal transport function. Curr Opin Clin Nutr Metab Care 4: 351-354.
4. Söderholm JD, Hedman L, Artursson P, Franzén L, Larsson J, Pantzar N, Permert J. 1998. Integrity and metabolism of human ileal mucosa in vitro in the Ussing chamber. Acta Physiol Scand 162: 47-56.
5. Polentarutti BI, Peterson AL, Sjoberg AK, Anderberg EKI, Utter LM, Ungell AB. 1998. Evaluation of viability of excised rat intestinal segments in the Ussing chamber: Investigation of morphology, electrical parameters, and permeability characteristics. Pharm Res 16: 446-454.
6. Yang H, Soderholm JD, Larsson J, Permert J, Lindgren J, Wiren M. 2000. Bidirectional supply of glutamine maintains enterocyte ATP content in the in vitro Ussing chamber model. Int J Colorectal Dis 15: 291-296.
7. Bajka BH, Gillespie CM, Steeb C-B, Read LC, Howarth GS. 2003. Applicability of the Ussing chamber technique to permeability determinations in functionally distinct regions of the gastrointestinal tract in the rat. Scand J Gastroenterol 38: 732-741.
8. Hoshi T, Suzuki Y, Kusachi T. Igarashi Y. 1976. Interrelationship between sugar-evoked increases in transmural potential difference and sugar influxes across the mucosal border in the small intestine. Tohoku J Exp Med 119:201-209.
9. Field M. 2003. Intestinal ion transport and the pathophysiology of diarrhea. J Clin Invest 111: 931-943.
10. Plumb JA, Burston D, Baker TG. Gardner ML. 1987. A comparison of the structural integrity of several commonly used preparations of rat small intestine in vitro. Clin Sci 73: 53-59.
11. Kozar RA, Schultz SG, Hassoun HT. Desoignie R, Weisbrodt NW, Haber MM, Moore FA. 2002. The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats. Gastroenterology 123: 810-816.
12. Matsuno K. 2004. Segmental difference in epithelial and mucosal barrier functions between the jejunum and the ileum in cold storage small bowel grafts in the rat. Kurume Med J 51: 35-41.
13. Takeyoshi I, Zhang S, Nomoto M, Zhu Y, Kokudo Y, Suzuki T, Hamada N, Nemoto A, Starzl TE, Todo S. 2001. Mucosal damage and recovery of the intestine after prolonged preservation and transplantation in dogs. Transplantation 71: 1-7.
14. Brennan PC, McCullough JS, Carr KE. 1999. Variations in cell and structure populations along the length of murine small intestine. Cells Tissues Organs 164: 221-226.
15. +/glucose cotransporter and mRNA along the crypt-villus axis of rabbit small intestine. Biochem Biophys Res Commum 181: 1208-1217.