Empiric treatment with high and standard dose of omeprazole in general practice: Two-week randomized placebo-controlled trial and 12-month follow-up of health-care consumption

American Journal of Gastroenterology

Volumn 99, Issue 6, 2004, Pages 1050-1058

  Meineche Schmidt, Villy ^a  

^a NONE   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

OMEPRAZOLE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DYSPEPSIA; FEMALE; GENERAL PRACTITIONER; HEALTH CARE UTILIZATION; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; SYMPTOM;

ADULT; AGED; DELIVERY OF HEALTH CARE; DENMARK; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DYSPEPSIA; ENZYME INHIBITORS; FAMILY PRACTICE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; OMEPRAZOLE; PATIENT SATISFACTION; PROBABILITY; RECURRENCE; REFERENCE VALUES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 3142783775     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2004.30089.x     Document Type: Article

References (25)

1. Folkersen BH, Larsen B, Quist P. General practitioners handling of patients with dyspepsia. Ugeskr Læger 1997;159:3777-81.
2. Heikkinen M, Pikkarainen P, Takala J, et al. General practitioners approach to dyspepsia. Scand J Gastroenterol 1996;31:648-53.
3. Meineche-Schmidt V, Jorgensen T. Investigation and therapy in patients with different types of dyspepsia. Fam Pract 2000;17:514-21.
4. Bodger K, Daly MJ, Heatley RV. Prescribing patterns for dyspepsia in primary care. Aliment Pharmacol Ther 1996;10:889-95.
5. Meineche-Schmidt V, Krag E. Antisecretory therapy in 1017 patients with ulcerlike or refluxlike dyspepsia in general practice. Eur J Gen Pract 1997;3:125-30.
6. Mason I, Millar LJ, Sheikh RR, et al. The management of acid related dyspepsia in general practice: A comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Aliment Pharmacol Ther 1998;12:263-71.
7. Goves J, Oldring JK, Kerr D, et al. First line treatment with omeprazole provides an effective and superior alternative strategy in the management of dyspepsia compared to antacid/alginate liquid: A multicentre study in general practice. Aliment Pharmacol Ther 1998;12:147-57.
8. Talley NJ, Meineche-Schmidt V, Paré P, et al. Efficacy of omeprazole in functional dyspepsia: double-blind, randomised, placebo-controlled trials (the Bond and Opera studies). Aliment Pharmacol Ther 1998;12:1055-65.
9. Triadafilopoulus G. Proton pump inhibitors for Barrett's oesophagus. Gut 2000;46:144-6.
10. Hendel J, Hendel L, Hage E, et al. Monitoring of omeprazole treatment in gastro-oesophageal reflux disease. Eur J Gastroenterol Hepatol 1996;8:413-4.
11. Meineche-Schmidt V, Talley NJ, et al. Impact of functional dyspepsia on quality of life and health care consumption after cessation of antisecretory treatment. Scand J Gastroenterol 1999;34:566-74.
12. Lydeard S, Jones R. Factors affecting the decision to consult with dyspepsia: Comparison of consulters and non-consulters. J R Coll Gen Pract 1989;39:495-8.
13. Howell S, Talley NJ. Does fear of serious disease predict consulting behaviour among patients with dyspepsia in general practice? Eur J Gastroenterol Hepatol 1999;11:881-6.
14. Leder D. Clinical interpretation: The hermeneutics of medicine. Theor Med 1990;11:9-24.
15. Lock JD. Some aspects of medical hermeneutics: The role of dialectic and narrative. Theor Med 1990;11:41-9.
16. Wulff HR, Pedersen SA, Rosenberg R. Philosophy of medicine. Blackwell Scientific Publications Limited, Oxford, 1986.
17. Svenaeus F. The hermeneutics of medicine and the phenomenology of health. Kluwer Academic Publishers, Dordrecht, the Netherlands, 2000.
18. Locke CR, Talley NJ, et al. Helicobacter pylori and dyspepsia: A population-based study on the organism and host. Am J Gastroenterol 2000;95:1906-13.
19. Rosenstock S, Kay L, et al. Relation between Helicobacterpylori infection and gastrointestinal symptoms and syndromes. Gut 1997;41:169-76.
20. Lee JM, O'Morain CA. Different management for Helicobacter pylori positive and negative patients with gastroesophageal reflux disease? Gut 1998;3:14-20.
21. Andersen LP, Rosenstock SJ, et al. Seroprevalence of immunoglobulin G, M and A antibodies against Helicobacter pylori in an unselected Danish population. Am J Epidemiol 1996;143:1157-64.
22. Chiba N, Van Zanten SJ, Sinclair P, et al. Treating Helicobacter pylori infection in primary care patients with uninvestigated dyspepsia: The Canadian adult dyspepsia empiric treatment-Helicobacter pylori positive (CADET-Hp) randomised controlled trial. Br Med J 2002;324:1012-16.
23. Moayyedi P, Soo S, et al. Eradication of Helicobacterpylori for non-ulcer dyspepsia (Cochrane Review). The Cochrane Library, Issue 1, Oxford: Update Software, 2001.
24. Gilvarry J, Buckley MJ, et al. Eradication of Helicobacter pylori affects symptoms in non-ulcer dyspepsia. Scand J Gastroenterol 1997;32:1183-4.
25. Rubin GP, Meineche-Schmidt V, de Wit NJ, et al. The management of Helicobacter pylori infection in primary care. Guidelines from the ESPCG. Eur J Gen Pract 1999;5:98-104.