Effects of vitamin C and E on liver enzymes and biochemical parameters of rabbits exposed to aflatoxin B1

Veterinary and Human Toxicology

Volumn 46, Issue 4, 2004, Pages 190-192

  Karakilcik, Ali Ziya ^a   Zerin, Mustafa ^a   Arslan, Oktay ^a   Nazligul, Yasar ^a   Vural, Huseyin ^a  

^a HARRAN UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; DIMETHYL SULFOXIDE; LACTATE DEHYDROGENASE; LIVER ENZYME;

ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BIOTRANSFORMATION; BLOOD SAMPLING; CONTROLLED STUDY; ENZYME ACTIVITY; LIVER FUNCTION TEST; LIVER TOXICITY; NONHUMAN; RABBIT; VITAMIN INTAKE;

AFLATOXIN B1; ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASES; FEMALE; HEPATITIS, TOXIC; RABBITS; VITAMIN E;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 3142769127     PISSN: 01456296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Ronald KR, Yuan JM, Yu MC et al: Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma. Lancet 339: 943-946, 1992.
2. 1. Mutat Res 319: 309-316, 1993.
3. 1 in rabbit lung and liver microsomes. Carcinogenesis 11: 823-82, 1990.
4. 1-induced preneoplactic hepatic lesions in the rat. J Nutr 117: 1298-1302, 1987.
5. Kraus A, Roth HP, Kirchgessner M: Supplementation with vitamin C, vitamin E or β-carotene influences osmotic fragility and oxidative damage of erythrocytes of zinc-deficient rats. J Nutr 127: 1290-1296, 1997.
6. 1-treated male wistar rats: Preventive effect of picroliv. Pharm. Tox. 88: 53-58, 2001.
7. 1. Toxicol 43: 123-132, 1987.
8. 1 toxicosis in dairy calves pretreated with selenium-vitamin E. Am J Vet Res 47: 179-183, 1986.
9. Harvey RB, Kubena LF, Elissalde M: Influence of vitamin E on aflatoxicosis in groving swine. Am J Vet Res 55: 572-577, 1994.
10. Netke SP, Roomi MV, Tsao C et al: Ascorbic acid protects guinea pigs from acute aflatoxin toxicity. ToxicolAppl Pharmacol 143: 429-35, 1997.
11. Pegram RA, Wyatt RD: The relationship of certain blood parameters to aflatoxin resistance in Japanese quail. Poult Sci 65: 1652-1658, 1986.
12. 1-induced lipid peroxidation in rat liver. Toxicol. Appl Pharmacol 127: 145-150, 1994.
13. Duthie GG, Wahle WJ, James WT: Oxidant, antioxidant and cardiovascular diseases. Nutr Res Rev 2: 51-62, 1994.
14. Sies H, Stahl W, Sundquist AR: Antioxidant functions of vitamins: Vitamins C&E, β-carotene and other carotenoids. Ann NewYork Acad Sci 669: 7-21, 1992.
15. Abdelhamid AM, El-Shawaf I, El-Ayoty SA: Effect of low level of dietary aflatoxins on baladi rabbits. Arch Anim Nutr 40: 517-537, 1990.
16. 1 binding to DNA in woodchuck hepatocytes. Cancer 73: 596-604, 1994.
17. 1-induced liver tumors by antioxidants with increased activity of microsomal enzymes. Indian J Med Res [B] 92: 332-336, 1990.
18. 1 hepatocorsinogenesis in the rat. Cancer Res 47: 5218-5223, 1987.
19. Murray RK, Granner DK, Mayes PA et al: Harper's Biochemistry, International Edition. Appleton and Lang, California: 649-664, 1988.
20. Karakylcyk AZ, Hayat A, Zerin M et al: Effects of intraperitoneally injected selenium and vitamin E in rats anesthetized with halothane. J Trace Elem Med Biol 17: 33-38, 2003.
21. McPherson A: Selenium, vitamin E and biological oxidation. In Cole DJ, Garnsworthy PJ eds Recent Advances in Animal Nutrition, Butterworth and Heinemann's, Oxford: 3-30, 1994.
22. Olmez D, Karakylcyk AZ: Protective role of β-carotene dietary supplementation on activities of functional liver enzymes and some biochemical parameters in experimental hepatotoxicity of rats. J Nutr Biochem (in press).