Simultaneous stimulation of Fas-mediated apoptosis and blockade of costimulation prevent autoimmune diabetes in mice induced by multiple low-dose streptozotocin

Gene Therapy

Volumn 11, Issue 12, 2004, Pages 982-991

  Jin, Y ^a   Qu, A ^a   Wang, G M ^a   Hao, J ^a   Gao, X ^a   Xie, S ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Adenovirus vectors; Autoimmune diabetes; CTLA4lg; Fas ligand; Streptozotocin

Indexed keywords

ADENOVIRUS VECTOR; ALANINE AMINOTRANSFERASE; BUFFER; COMPLEMENTARY DNA; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FAS LIGAND; GLUCOSE; GREEN FLUORESCENT PROTEIN; PHOSPHATE; SODIUM CHLORIDE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGENICITY; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL STIMULATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG TOLERABILITY; FEASIBILITY STUDY; GENE THERAPY; GENE TRANSFER; IMMUNE RESPONSE; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; LIVER TOXICITY; LOW DRUG DOSE; MALE; MITOGENESIS; MOUSE; MULTIPLE DRUG DOSE; NONHUMAN; PANCREAS CELL; PRIORITY JOURNAL; SPLEEN CELL; STREPTOZOCIN DIABETES; T LYMPHOCYTE; TAIL; VIRAL GENE DELIVERY SYSTEM; VIRUS PLAQUE; VIRUS RECOMBINANT;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; APOPTOSIS; CELL DIVISION; DIABETES MELLITUS, EXPERIMENTAL; FAS LIGAND PROTEIN; GENE EXPRESSION; GENE THERAPY; ISLETS OF LANGERHANS; LIVER; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

ADENOVIRIDAE;

EID: 3142764720     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302260     Document Type: Article

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