Postmortem citalopram concentrations: Alone or along with other compounds

Journal of Forensic Sciences

Volumn 49, Issue 4, 2004, Pages 814-819

  Segua, Luis J ^a,b   Bravo, Begoña ^a  

^a Inst Anat Forense of Madrid (IAF)   (Spain)

^b Instituto Anatomico Forense   (Spain)

Author keywords

Alcohol; Blood levels; Citalopram; Fatal poisoning; Forensic science

Indexed keywords

ALCOHOL; ALPRAZOLAM; AMINOPHENAZONE; ANTIDEPRESSANT AGENT; BUFLOMEDIL; CARBOXYHEMOGLOBIN; CITALOPRAM; CLOZAPINE; COCAINE; CODEINE; DEXTROMETHORPHAN; DIAZEPAM; FLURAZEPAM; LEVOMEPROMAZINE; MAPROTILINE; MEPIVACAINE; MORPHINE; NORDAZEPAM; OLANZAPINE; OPIATE; OXAZEPAM; PSYCHOTROPIC AGENT; THIORIDAZINE; TRAMADOL; VENLAFAXINE;

ADULT; AGED; ARTICLE; AUTOPSY; CADAVER; CLINICAL ARTICLE; DEATH; DRUG BLOOD LEVEL; DRUG INTOXICATION; FEMALE; FORENSIC SCIENCE; HUMAN; MALE; PRIORITY JOURNAL; SPAIN; TOXICOLOGY;

ADULT; AGED; AGED, 80 AND OVER; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BENZODIAZEPINES; CAUSE OF DEATH; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITALOPRAM; ETHANOL; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GASTROINTESTINAL CONTENTS; HUMANS; MALE; MIDDLE AGED; NARCOTICS; PSYCHOTROPIC DRUGS;

EID: 3142762396     PISSN: 00221198     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. o, de Sanidad. November. 1998, Spain.
2. Worm K, Dragsholt C, Simonsen K, Kringsholm B. Citalopram concentrations in samples from autopsies and living persons. Int J Legal Med 1998;111:188-90.
3. Ostrom M, Eriksson A, Torzón J, Spigset O. Fatal overdose with citalopram. Lancet 1996;348:339-40.
4. Druid H, Holmgren P. A compilation of fatal and control concentrations of drugs in postmortem femoral drugs. J Forensic Sci 1997;42: 79-87.
5. Ohberg A, Vuori E, Klaukka T, Lonnqvist J. Antidepressants and suicide mortality. J Affect Disord 1998;50:225-33.
6. Overø KF. Preliminary studies of the kinetics of citalopram in man. Eur J Clin Pharmacology 1978;14:69-73.
7. Kragh-Sørensen P, Overø KF, Petersen OL, Jensen K, Parnas W. The kinetics of citalopram: single and multiple dose studies in man. Acta Pharmacol et Toxicol 1981;48:53-60.
8. Kristoffersen L, Bugge A, Lundanes E, Slørdal L. Simultaneous determination of citalopram, fluoxetine, paroxetine and their metabolites in plasma and whole blood by high-performance liquid chromatography with ultraviolet and fluorescence detection. J Chromatogr B 1999;774:229-46.
9. Personne M, Sjöberg G, Persson H. Citalopram overdose-review of cases treated in Swedish hospitals. Clin Toxicol 1997;35:237-40.
10. Winek CL, Wahba WW, Winek Jr. CL, Balzer TW. Drug and chemical blood-level data 2001. Forensic Sci Int 2001;122:107-23.
11. Overø KF. Fluorescence assay of citalopram and its metabolites in plasma by scanning densitometry of thin-layer-chromatograms. J Chromatogr 1981;224:526-31.
12. Øyehaug E, Østensen ET. High-performance liquid chromatographic determination of citalopram and four of its metabolites in plasma and urine samples from psychiatric patients. J Chromatogr 1984;308:199-208.
13. Macek J, Ptáček P, Klíma J. Rapid determination of citalopram in human plasma by high-performance liquid chromatography. J Chromatogr B 2001;755:279-85.
14. Eap CB, Bouchoux G, Amey M, Cochard N, Savary L, Baumann P. Simultaneous determination of human plasma levels of citalopram, paroxetine, sertraline, and their metabolites by gas chromatography-mass spectrometry. J Chromatogr Sci 1998;36:365-71.
15. Orden Ministerial del Ministerio de Justicia. 8 November 1996, BOE 23, December 1996.
16. Kalasinsky KS, Schaefer T, Binder SR. Forensic application of an automated drug-profiling system. J Anal Tox 1995;19(6):412-8.
17. Demedts P, Wauters A, Frandk F, Neels H. Evaluation of the REMEDI drug-profiling system. Eur J Clin Chem Clin Biochem 1994;32(5):409-17.
18. Ohtsuji M, Lai JS, Binder SR, Kondo T, Takayasu T, Ohshima T. Use of REMEDI HS in emergency toxicology for a rapid estimate of drug concentrations in urine, serum, and gastric samples. J Forensic Sci 1996;41(5):881-6.
19. Jonasson B, Saldeen T. Citalopram in fatal poisoning cases. Forensic Sci Int 2002;126:1-6.