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Volumn 39, Issue 7, 2004, Pages 629-633

Effect of sildenafil on gastric emptying and postprandial frequency of antral contractions in healthy humans

Author keywords

Frequency of antral contractions; Gastric emptying; Nitric oxide; Scintigraphy; Sildenafil

Indexed keywords

PLACEBO; SILDENAFIL;

EID: 3142759589     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520410005324     Document Type: Article
Times cited : (8)

References (30)
  • 1
    • 0031788009 scopus 로고    scopus 로고
    • Involvement of nitric oxide in human transient lower esophageal sphincter relaxations and esophageal primary peristalsis
    • Hirsch DP, Holloway RH, Tytgat GN, Boeckxstaens GE. Involvement of nitric oxide in human transient lower esophageal sphincter relaxations and esophageal primary peristalsis. Gastroenterology 1998;115:1374-80.
    • (1998) Gastroenterology , vol.115 , pp. 1374-1380
    • Hirsch, D.P.1    Holloway, R.H.2    Tytgat, G.N.3    Boeckxstaens, G.E.4
  • 2
    • 0036073618 scopus 로고    scopus 로고
    • Role of nitric oxide in gastric motor and sensory functions in healthy subjects
    • Kuiken SD, Vergeer M, Heisterkamp SH, Tytgat GN, Boeckxstaens GEE. Role of nitric oxide in gastric motor and sensory functions in healthy subjects. Gut 2002;51:212-8.
    • (2002) Gut , vol.51 , pp. 212-218
    • Kuiken, S.D.1    Vergeer, M.2    Heisterkamp, S.H.3    Tytgat, G.N.4    Gee, B.5
  • 3
    • 0028006769 scopus 로고
    • Inhibition of nitric oxide synthase delays gastric emptying of solid meals
    • Orihata M, Sarna SK. Inhibition of nitric oxide synthase delays gastric emptying of solid meals. J Pharmacol Exp Ther 1994;271: 660-70.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 660-670
    • Orihata, M.1    Sarna, S.K.2
  • 4
    • 0030055610 scopus 로고    scopus 로고
    • Nitric oxide mediates mechano- and chemoreceptor-activated intestinal feedback control of gastric emptying
    • Orihata M, Sarna SK. Nitric oxide mediates mechano- and chemoreceptor-activated intestinal feedback control of gastric emptying. Dig Dis Sci 1996;41:1303-9.
    • (1996) Dig Dis Sci , vol.41 , pp. 1303-1309
    • Orihata, M.1    Sarna, S.K.2
  • 6
    • 0032502708 scopus 로고    scopus 로고
    • Sildenafil, a novel inhibitor of phosphodiesterase type 5 in human corpus cavernosum muscle cells
    • Moreland RB, Goldstein I, Traish A. Sildenafil, a novel inhibitor of phosphodiesterase type 5 in human corpus cavernosum muscle cells. Life Sci 1998;62:309-18.
    • (1998) Life Sci , vol.62 , pp. 309-318
    • Moreland, R.B.1    Goldstein, I.2    Traish, A.3
  • 7
    • 0026460941 scopus 로고
    • Role of nitric oxide in gastrointestinal and hepatic function and disease
    • Stark ME, Szurszewski JH. Role of nitric oxide in gastrointestinal and hepatic function and disease. Gastroentrology 1992;103:1928-49.
    • (1992) Gastroentrology , vol.103 , pp. 1928-1949
    • Stark, M.E.1    Szurszewski, J.H.2
  • 8
    • 0023932256 scopus 로고
    • Motor activity of the gastric antrum, pylorus, and duodenum under fasted conditions and after a liquid meal
    • Houghton LA, Read NW, Heddle F, Maddern GJ, Downton J, Toouli J, et al. Motor activity of the gastric antrum, pylorus, and duodenum under fasted conditions and after a liquid meal. Gastroenterology 1988;94:1276-84.
    • (1988) Gastroenterology , vol.94 , pp. 1276-1284
    • Houghton, L.A.1    Read, N.W.2    Heddle, F.3    Maddern, G.J.4    Downton, J.5    Toouli, J.6
  • 9
    • 0034331781 scopus 로고    scopus 로고
    • A simplified method for processing dynamic images of gastric antrum
    • Madsen JL, Graff J, Fugisang S. A simplified method for processing dynamic images of gastric antrum. Nucl Med Commun 2000;21:1037-41.
    • (2000) Nucl Med Commun , vol.21 , pp. 1037-1041
    • Madsen, J.L.1    Graff, J.2    Fugisang, S.3
  • 11
    • 0026418189 scopus 로고
    • Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid
    • Desai KM, Sessa WC, Vane JR. Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid. Nature 1991;351:477-9.
    • (1991) Nature , vol.351 , pp. 477-479
    • Desai, K.M.1    Sessa, W.C.2    Vane, J.R.3
  • 12
    • 0034932886 scopus 로고    scopus 로고
    • New issues about nitric oxide and its effects on the gastrointestinal tract
    • Martin MJ, Jimenez MD, Motilva V. New issues about nitric oxide and its effects on the gastrointestinal tract. Curr Pharm Des 2001;7:881-908.
    • (2001) Curr Pharm des , vol.7 , pp. 881-908
    • Martin, M.J.1    Jimenez, M.D.2    Motilva, V.3
  • 13
    • 0033958037 scopus 로고    scopus 로고
    • Effects of sildenafil on esophageal motility of patients with idiopatic achalasia
    • Bortolotti M, Mari C, Lopilato C, Porrazzo G, Miglioli M. Effects of sildenafil on esophageal motility of patients with idiopatic achalasia. Gastroenterology 2000;118:253-7.
    • (2000) Gastroenterology , vol.118 , pp. 253-257
    • Bortolotti, M.1    Mari, C.2    Lopilato, C.3    Porrazzo, G.4    Miglioli, M.5
  • 14
    • 0035659733 scopus 로고    scopus 로고
    • The effect of sildenafil on lower esophageal sphincter and body motility in normal male adults
    • Rhee PL, Hyun JG, Lee YH, Kim YH, Son HJ, Kim JJ, et al. The effect of sildenafil on lower esophageal sphincter and body motility in normal male adults. Am J Gastroenterol 2001;96: 3251-7.
    • (2001) Am J Gastroenterol , vol.96 , pp. 3251-3257
    • Rhee, P.L.1    Hyun, J.G.2    Lee, Y.H.3    Kim, Y.H.4    Son, H.J.5    Kim, J.J.6
  • 15
    • 0036103111 scopus 로고    scopus 로고
    • Effect of sildenafil on oesophageal motor function in healthy subjects and patients with oesophageal motor disorders
    • Eherer AJ, Schwetz I, Hammer HF, Petnehazy T, Schneidl SJ, Weber K, et al. Effect of sildenafil on oesophageal motor function in healthy subjects and patients with oesophageal motor disorders. Gut 2002;50:758-64.
    • (2002) Gut , vol.50 , pp. 758-764
    • Eherer, A.J.1    Schwetz, I.2    Hammer, H.F.3    Petnehazy, T.4    Schneidl, S.J.5    Weber, K.6
  • 17
    • 0033847010 scopus 로고    scopus 로고
    • Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy
    • Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, et al. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy. J Clin Invest 2000;106:373-84.
    • (2000) J Clin Invest , vol.106 , pp. 373-384
    • Watkins, C.C.1    Sawa, A.2    Jaffrey, S.3    Blackshaw, S.4    Barrow, R.K.5    Snyder, S.H.6
  • 20
    • 0036121963 scopus 로고    scopus 로고
    • Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: Absolute bioavailablity, food effects and dose proportionality
    • Nichols DJ, Muirhead GJ, Harness JA. Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailablity, food effects and dose proportionality. Br J Clin Pharmacol 2002;53 Suppl 1:5S-12S.
    • (2002) Br J Clin Pharmacol , vol.53 , Issue.1 SUPPL.
    • Nichols, D.J.1    Muirhead, G.J.2    Harness, J.A.3
  • 21
    • 0028903412 scopus 로고
    • The migrating motor complex modulates intestinal motility response and rate of gastric emptying of caloric meals
    • Medhus A, Sandstad O, Bredesen J, Husebye E. The migrating motor complex modulates intestinal motility response and rate of gastric emptying of caloric meals. Neurogastroenterol Motil 1995;7:1-8.
    • (1995) Neurogastroenterol Motil , vol.7 , pp. 1-8
    • Medhus, A.1    Sandstad, O.2    Bredesen, J.3    Husebye, E.4
  • 22
    • 0029886718 scopus 로고    scopus 로고
    • The relationship between gut hormone secretion and gastric emptying in different phases of the migrating motor complex
    • Rasmussen L, Oster-Jorgensen E, Qvist N, Hoist JJ, Rehfeld JF, Hovendal CP, et al. The relationship between gut hormone secretion and gastric emptying in different phases of the migrating motor complex. Scand J Gastroenterol 1996;31:458-62.
    • (1996) Scand J Gastroenterol , vol.31 , pp. 458-462
    • Rasmussen, L.1    Oster-Jorgensen, E.2    Qvist, N.3    Hoist, J.J.4    Rehfeld, J.F.5    Hovendal, C.P.6
  • 24
    • 0029151133 scopus 로고
    • Nitric oxide, an enteric nonadrenergic-noncholinergic relaxant transmitter: Evidence using phosphodiesterase V and nitric oxide synthase inhibition
    • Williams SJ, Parsons ME. Nitric oxide, an enteric nonadrenergic- noncholinergic relaxant transmitter: evidence using phosphodiesterase V and nitric oxide synthase inhibition. Br J Pharmacol 1995;116:1789-96.
    • (1995) Br J Pharmacol , vol.116 , pp. 1789-1796
    • Williams, S.J.1    Parsons, M.E.2
  • 25
    • 0000101927 scopus 로고
    • Interstitial cells of Cajal
    • Sect. 6, Bethesda, MD: American Physiological Society
    • Thuneberg L. Interstitial cells of Cajal. In: Handbook of physiology. The gastrointestinal system. Sect. 6, vol. 1. Bethesda, MD: American Physiological Society; 1989. p. 349-86.
    • (1989) Handbook of Physiology. The Gastrointestinal System , vol.1 , pp. 349-386
    • Thuneberg, L.1
  • 26
    • 0029819577 scopus 로고    scopus 로고
    • Abnormal gastric myoelectrical activity and delayed gastric emptying in patients with symptoms suggestive of gastroparesis
    • Chen JD, Lin Z, Pan J, McCallum RW. Abnormal gastric myoelectrical activity and delayed gastric emptying in patients with symptoms suggestive of gastroparesis. Dig Dis Sci 1996;41: 1538-45.
    • (1996) Dig Dis Sci , vol.41 , pp. 1538-1545
    • Chen, J.D.1    Lin, Z.2    Pan, J.3    McCallum, R.W.4
  • 27
    • 0030842575 scopus 로고    scopus 로고
    • Interstitial cells of Cajal as targets for pharmacological intervention in gastrointestinal motor disorders
    • Huizinga JD, Thuneberg L, Vanderwinden JM, Rumessen JJ. Interstitial cells of Cajal as targets for pharmacological intervention in gastrointestinal motor disorders. Trends Pharmacol Sci 1997;18:393-403.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 393-403
    • Huizinga, J.D.1    Thuneberg, L.2    Vanderwinden, J.M.3    Rumessen, J.J.4
  • 28
    • 0026521720 scopus 로고
    • Nitric oxide as mediator of nonadrenergic noncholinergic neurotransmission
    • Sanders KM, Ward SM. Nitric oxide as mediator of nonadrenergic noncholinergic neurotransmission. Am J Physiol 1992; 262:G379-92.
    • (1992) Am J Physiol , vol.262
    • Sanders, K.M.1    Ward, S.M.2
  • 29
    • 0037236431 scopus 로고    scopus 로고
    • Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum
    • Kito Y, Suzuki H. Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum. J Physiol 2003; 546:191-205.
    • (2003) J Physiol , vol.546 , pp. 191-205
    • Kito, Y.1    Suzuki, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.