Apoptosis and p53, Bcl-2 and Bax gene expression in parathyroid glands of patients with hyperparathyroidism

Pathology and Oncology Research

Volumn 10, Issue 2, 2004, Pages 98-103

  Szende, Béla ^a   Farid, Parvaneh ^a   Végso, Gyula ^a   Perner, Ferenc ^a   Kopper, László ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Adenoma; Apoptosis; Bax; Bcl 2; Carcinoma; Hyperplasia; Mitosis; p53; Parathyroid

Indexed keywords

GENE PRODUCT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ARTICLE; CELL DEATH; CELL POPULATION; CELL PROLIFERATION; GENE LOCATION; HUMAN; HYPERPARATHYROIDISM; INCIDENCE; KIDNEY FAILURE; KIDNEY FUNCTION; LABORATORY DIAGNOSIS; MAJOR CLINICAL STUDY; MITOSIS; PARATHYROID CELL; PARATHYROID GLAND; PRIMARY HYPERPARATHYROIDISM; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SECONDARY HYPERPARATHYROIDISM; STATISTICAL SIGNIFICANCE; SYMPTOMATOLOGY; THYROID PARAFOLLICULAR CELL;

EID: 3142758521     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02893463     Document Type: Article

References (12)

1. Roth SJ: The parathyroid gland. In Silverberg, S G. Principals and practice of surgical pathology. Second edition. Churchill Livingstone, New York, pp; 1923-1955, 1990
2. Reiss E, Counterbury I M. Spectrum of hyperparathyroidism. Am J Med 56: 784-810, 1974
3. Koea JB, Shaw JH: Parathyroid cancer: Biology and management. Surg Oncol 8: 155-165, 1999
4. Bocsi J, Perner F, Szücs J, et al: DNA content of parathyroid tumors, Anticancer Res 18: 2901-2904, 1998
5. Ricci F, Mingazzini PL, Sebastiani V, et al: P53 as a marker of differentiation between hyperplastic and adenomatous lesions of parathyroids. Int Diag Pathol 6: 229-235, 2002
6. Stojadinovic A, Hoos A, Nissan A, et al: Cordon-Cardo C, Shaha AR, Brennan MF, Singh B, Gossein RA. Parathyroid neoplasms: Clinical, histopathological, and tissue microarray-based molecular analysis. Hum Pathol 34: 54-64, 2003
7. Abbona GC, Papotti M, Gasparri G, et al: Proliferative activity in parathyroid tumors as detected by Ki-67 immunostaining. Hum Pathol 26: 135-138, 1995
8. Vargas MP, Vargas HI, Kleiner DE, et al: The role of prognostic markers (MIB-1, RB, and Bcl-2) in the diagnosis of parathyroid tumors. Mod Pathol 10: 12-17, 1997
9. Erikson LA, Jin L, Wollan P, et al: Parathyroid hyperplasia, adenomas and carcinomas: Differential expression of P27 protein. Am J Surg Pathol 23: 288-295 1999
10. Schantz A, Castleman B: Parathyroid carcinoma: A study of 70 cases. Cancer 31: 600-605, 1973
11. Snover DC,Foukar K: Mitotic activity in benign parathyroid disease. Am J Clin Pathol 75: 355-347, 1981
12. Zang Y, Xiong Y: P53 amino terminal nuclear signal inhibited by DNA damage-induced phosphorylation. Science 292: 1910-1915, 2000