[123/131I]Iodometomidate as a radioligand for functional diagnosis of adrenal disease: Synthesis, structural requirements and biodistribution

Radiochimica Acta

Volumn 92, Issue 4-6, 2004, Pages 297-303

  Schirbel, A ^a   Zolle, I ^b   Hammerschmidt, F ^c   Berger, M L ^c   Schiller, D ^a   Kvaternik, H ^d   Reiners, Chr ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

^d ARC SEIBERSDORF RESEARCH GMBH   (Austria)

Author keywords

131I IMTO; Adrenal scintigraphy; Inhibitor of 11 hydroxylase; Metomidate; SPECT

Indexed keywords

CYTOCHROME P450 INHIBITOR; ESTER; ETOMIDATE; IODINE 123; IODINE 131; IODOMETOMIDATE I 123; IODOMETOMIDATE I 131; METOMIDATE; RADIOLIGAND; UNCLASSIFIED DRUG;

ADOLESCENT; ADRENAL DISEASE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CONTRAST; DEIODINATION; DRUG BINDING; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; EX VIVO STUDY; FEMALE; IN VITRO STUDY; ISOTOPE LABELING; LIGAND BINDING; MALE; NONHUMAN; OXIDATION; RADIOACTIVITY; RADIOIODODESTANNYLATION; RADIOISOTOPE DISTRIBUTION; RADIOLIGAND BINDING; RADIOSYNTHESIS; RAT; REACTION OPTIMIZATION; SPECTROMETRY; STEREOCHEMISTRY;

EID: 3142757820     PISSN: 00338230     EISSN: None     Source Type: Journal    
DOI: 10.1524/ract.92.4.297.35598     Document Type: Article

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