Further metalations and functionalizations of chloro-, bromo- and iodo(trifluoromethyl)pyridines

Synthesis

Volumn , Issue 10, 2004, Pages 1619-1624

  Cottet, Fabrice ^a   Marull, Marc ^a   Mongin, Florence ^b,c   Espinosa, David ^b   Schlosser, Manfred ^a,b  

^a Institut de chimie moleculaire et biologique Ecole Polytechnique Federale de Lausanne   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c IRCOF   (France)

Author keywords

Halogen migration; Halogen metal permutation ('exchange'); Lithium diisopropylamide; Metalations; Pyridines; Site selectivity

Indexed keywords

ALDEHYDES; AROMATIC COMPOUNDS; CARBOXYLATION; CARBOXYLIC ACIDS; IODINE; SYNTHESIS (CHEMICAL);

METALATIONS; REGIOEXHAUSTIVE FUNCTIONALIZATION;

NITROGEN COMPOUNDS;

2 BROMO 4 (TRIFLUOROMETHYL)PYRIDINE; 2 BROMO 5 (TRIFLUOROMETHYL)PYRIDINE; 2 BROMO 6 (TRIFLUOROMETHYL)PYRIDINE; 2 IODO 4 (TRIFLUOROMETHYL)PYRIDINE; 3 CHLORO 2 (TRIFLUOROMETHYL)PYRIDINE; 4 IODO 2 (TRIFLUOROMETHYL)PYRIDINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXYLATION; ELECTROCHEMISTRY; PROTON TRANSPORT; STEREOCHEMISTRY;

EID: 3142746851     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-829111     Document Type: Article

References (12)

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