Effect of antioxidant ascorbic acid, 1-methionine or α tocopherol alone or along with chelator on cardiac tissue of lead-treated rats

Veterinarski Arhiv

Volumn 74, Issue 3, 2004, Pages 235-244

  Patra, R C ^a   Swarup, D ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Antioxidant; Chelator; Heart; Lead; Rat

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CHELATING AGENT; LEAD; LIPID PEROXIDE; METHIONINE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOACCUMULATION; CHELATION; CONTROLLED STUDY; DRUG EFFECT; EXPOSURE; FEMALE; HEART; LIPID PEROXIDATION; MALE; NONHUMAN; RANDOMIZATION; STATISTICAL SIGNIFICANCE; TISSUE LEVEL;

ANIMALIA;

EID: 3142746048     PISSN: 03725480     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. ASHOKAN, S. K. (1974): Experimental lead cardiomyopathy: myocardial structural changes in rats given small amounts of lead. J. Lab. Clin. Med. 84, 20-25.
2. BENER, A., E. OBINECHE, M. GILLETT, M. A. PASHA, R. BISHAWI (2001): Association between blood levels of lead, blood pressure and risk of diabetes and heart disease in workers. Int. Arch. Occupational Environ. Health. 74, 375-378.
3. BETTIGER, W. J., P. G. REEVES, J. E. SAVAGE, B. L. O'DELL (1980): Interaction of zinc and vitamin E in the chick. Proceedings of the Society for Experimental Biology and Medicine 163, 432-436.
4. BUETTER, G. R. (1993): The peeking order of free radicals and antioxidants: lipid peroxidation, α tocopherol, and ascorbate. Arch. Biochem. Biophys. 300, 535-543.
5. CINI, M., R. Y. FARIELLO, A. BIANCHETTEI, A. MORETTI (1994): Studies on lipid peroxidation in the rat brain. Neurochem. Res. 19, 283-288.
6. CORYSLECHTA, D. A., B. WEISS, C. COX (1987): Mobilization and redistribution of lead over the course of calcium disodium ethylenediamine tetraacetate chelation therapy. J. Pharmacol. Exp. Ther. 243, 804-813.
7. DEY, S., D. SWARUP, G. R. SINGH (1993): Effects of experimental lead toxicity on cardiovascular functions in calves. Vet. and Human Toxicol. 35, 501-503
8. DOYLE, J. J., R. L. YOUNGER (1984): Influence of ingested led on distribution of lead, iron, zinc, copper and manganese in bovine tissues. Vet. Human. Toxicol. 26, 201-204.
9. ERCAL, N., P. TRERATPHAN, T. C. HAMMOND, R. H. MATHEWS, N. H. GRANNEMAAN, D. R. SPITZ (1996): In vivo indices of oxidative stress in lead-exposed C57BL/6 mice are reduced by treatment with meso-2, 3-dimercaptosuccinic acid or N-acetyl cysteine. Free Rad. Biol. Med. 21, 157-161.
10. EVANS, P., B. HALLIWELL (2001): Micronutrients. Oxidant/antioxidant status. British J. Nutr. 85s, 57-74.
11. FICK, K. R., C. R. AMMERMAN, S. M. MILLER, C. F. SIMPSON, P. F. LOGGINS (1976): Effect of dietary lead on performance, tissue mineral composition and lead absorption in sheep. J. Anim. Sci. 42, 515-523.
12. GOYER, R. A., M. G. CHERION (1979): Ascorbic acid and EDTA treatment of lead toxicity in rats. Life Sci. 24, 433-438.
13. GURER, H., M. G. OZGUNES, R. NEAL, D. R. SPITZAND, N. ERCAL (1998): Antioxidant effects of N-acetyl cystein and succimer in red blood cells from lead exposed rats. Toxicol. 128, 181-189.
14. HALLIWELL, B. (1994): Free radicals, antioxidants and human disease: curiosity, cause and consequence? Lancet 344, 721-724.
15. HSU, P. C., M. Y. LIU, C. C. HSU, L. Y. CHEN, Y. L. GUO (1998): Effect vitamin E and/or C on reactive oxygen species related lead toxicity in the rat sperm. Toxicol. 128, 169-179.
16. JONES, D. P., V. E. KAGEN, S. D. AUST, D. J. REED, S. T. OMAYE (1995): Impact of nutrients on cellular lipid peroxidation and antioxidant defense system. Fund. Applied Toxicol. 26, 1-7.
17. KHAN, M. Z., J. SZAREK, K. MARKIEWIEZ (1993): Effects of oral administration of toxic levels of lead and selenium upon concentration of different elements in liver of broiler chicks. J. Vet. Med. Series A 40, 652-664.
18. KOLMER, J. A., E. H. SPAULDING, H. W. ROBINSON (1951): Approved laboratory Techniques. Appleton Century Crafts, New York, pp. 1090-1091.
19. MEISTER, A. (1981): On the cycles of glutathione metabolism and transport. Current Topic Cellular Regulation 18, 21-58.
20. MONTEIRO, H. P., B. S. P. ABDALLA, A. S. ARCURI, E. H. J. BECHERA (1985): Oxygen toxicity related to exposure to lead. Clin. Chem. 31, 1673-1676.
21. OHKAWA, N., N. OHISHI, K. YAGI (1979): Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochem. 95, 351-358.
22. PATRA, R. C., D. SWARUP, S. K. DWIVEDI (2001): Antioxidant effects of α tocopherol, ascorbic acid and L-methionine on lead-induced oxidative stress to the liver, kidney and brain in rats. Toxicol. 162, 81-89.
23. PATRA, R. C., D. SWARUP, S. K. DWIVEDI, A. SAHOO (2001): Trace minerals in blood of young calves during exposure to lead. Indian J. Anim. Sci. 71, 507-510.
24. QUINLAN, G. J., B. HALLIWELL, C. P. MOORHOUSE, J. M. C. GUTTERIDGE (1988): Action of lead (II) and aluminum (III) ions on iron-stimulated lipid peroxidation in liposomes, erythrocytes and rat liver microsomal fractions. Biochem. Biophys. Acta 962, 196-200.
25. SANDHIR, R., K. D. GILL (1995): Effect of lead on lipid peroxidation in liver of rats. Biol. Trace Elem. Res. 48, 91-97.
26. SANDHIR, R., D. JULKA, K. D. GILL (1994): Lipid peroxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes. Pharmacol. Toxicol. 74, 66-71.
27. SHAABAN, A. A., A. A. SHOHATA, T. A. IBRAHIM, A. H. SEDDEK, A. A. EL-SHREIF (1992): Relationship between certain body electrolytes and lead toxicity in exposed cattle. Assuit Vet. Med. J. 27, 205-206
28. SINGH, N. P., I. S. THIND, L. F. VITALE, M. PAWLOW (1976): Lead content of tissues of baby rats born of, and nourished by lead-poisoned mothers. J. Lab. Clin. Med. 87, 273-280.
29. th ed., Iowa State University Press. USA.
30. TSAO, D. A., H. S. YU, J. T. CHEN, C. K. HO, H. R. CHANG (2000): The change of beta adrenergic system in lead induced hypertension. Toxicol. Applied Pharmacol. 164, 127-133.
31. UTLEY, H. G., F. BERNHEIM, P. HOCHSEIM (1967): Effect of sulfahydryl reagents on peroxidation of microsomes. Arch. Biochem. Biophys. 118, 29-32.
32. VAZIRI, N. D., Y. DING, Z. NI (2001): Compensatory upregulation of nitric oxide synthase isoforms in lead induced hypertension; reversed by superoxide dismutase mimetic drug. J. Pharmacol. Exp. Ther. 298, 679-685.
33. VIJ, A. G., N. K. SATIJA, S. J. FLORA (1998): Lead induced disorders in hematopoeitic and drug metabolism enzyme system and their protection by ascorbic acid supplementation. Biomed. Environ. Sci. 11, 7-14.