Synthesis and biological evaluation of ebselen and its acyclic derivatives

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 12, 2003, Pages 1413-1416

  Chang, Tsu Chung ^b   Huang, Mei Lan ^a   Hsu, Wen Lin ^d   Hwang, Jing Min ^c   Hsu, Ling Yih ^a  

^a Grad Inst of Pharmacognosy Science   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

Antioxidant; Ebselen derivative; Glutathione peroxidase; Peroxynitrite; Selenoorganic compound

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 (2 METHOXYBENZYL) 1,2 BENZISOSELENAZOL 3(2H) ONE; 2 (2 METHYLPHENYL) 1,2 BENZISOSELENAZOL 3(2H) ONE; 2 (3 METHYLPHENYL) 1,2 BENZISOSELENAZOL 3(2H) ONE; 2 (4 METHOXYBENZYL) 1,2 BENZISOSELENAZOL 3(2H) ONE; 2 (4 METHYLPHENYL) 1,2 BENZISOSELENAZOL 3(2H) ONE; EBSELEN; EBSELEN DERIVATIVE; GLUTATHIONE PEROXIDASE; N PHENYL (2 ALLYLSELENO)BENZOYLAMIDE; N PHENYL N METHYL (2 METHYLSELENO)BENZOYLAMIDE; N TOLUIDYL N METHYL (2 METHYLSELENO)BENZOYLAMIDE; ORGANOSELENIUM DERIVATIVE; PEROXYNITRITE; SCAVENGER; UNCLASSIFIED DRUG; ALIPHATIC HYDROCARBON; PYRROLE DERIVATIVE;

ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVITY; METHODOLOGY; SYNTHESIS;

AZOLES; DRUG EVALUATION, PRECLINICAL; FREE RADICAL SCAVENGERS; HYDROCARBONS, ACYCLIC; ORGANOSELENIUM COMPOUNDS;

EID: 3142744170     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.1413     Document Type: Article

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